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  • Book
  • © 2015

Serotonin Receptor Technologies

  • Includes cutting-edge methods and protocols involving the serotonergic system
  • Provides vital details essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 95)

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Table of contents (12 protocols)

  1. Front Matter

    Pages i-xii
  2. Receptor Dimerization

    1. Front Matter

      Pages 1-1
    2. Novel Approaches to Serotonin Receptor Interaction Studies

      • Sylwia Łukasiewicz, Ewa Błasiak, Kinga Szafran-Pilch, Marta Dziedzicka-Wasylewska
      Pages 3-20
    3. Techniques for the Study of GPCR Heteromerization in Living Cells and Animal Models

      • José L. Moreno, Jeremy Seto, James B. Hanks, Javier González-Maeso
      Pages 21-36
  3. Manipulation and Analysis of Serotonergic Signaling in Brain Slices

    1. Front Matter

      Pages 37-37
  4. Mouse Models to Study Serotonin-Associated Behavioral Disorders

    1. Front Matter

      Pages 57-57
    2. The Murine Serotonin Syndrome and the 5-HT1A Receptor: Behavioral Effects and Hypothermia

      • Robert Haberzettl, Heidrun Fink, Silke Dietze, Bettina Bert
      Pages 83-100
    3. 5-HT4 Receptor Subtype, β-Arrestin Level, and Rapid-Onset Effects of Antidepressant Drugs

      • Indira Mendez-David, Denis Joseph David, Jean-Philippe Guilloux, René Hen, Alain Michel Gardier
      Pages 101-121
  5. Serotonin Transporter

    1. Front Matter

      Pages 123-123
  6. Back Matter

    Pages 241-245

About this book

Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na+-dependent serotonin transporter (SERT), this volume provides state of the art methodologies currently applied in serotonin research from leading experts in the field. Serotonin Receptor Technologies describes approaches that vary from molecular biological and biochemical techniques (e.g., regarding receptor dimerization), fluorescence microscopy and imaging applications, flow cytometry, the use of organotypic slice and cell cultures to the generation of genetically modified animal models and the development of sophisticated behavioral tests, thus covering a wide spectrum of techniques to study serotonergic signaling in detail. Written for the popular Neuromethods series, chapters include the kind of detail and practical advice that ensures successful results in the lab.

Authoritative and convenient, Serotonin Receptor Technologies serves to foster both basic and translational research aiming to further deepen our understanding of the various facets of aminergic systems, as well as to aid research on similar problems with related GPCRs and neurotransmitter transporters.

Editors and Affiliations

  • Universität zu Köln, Köln, Germany

    Wolfgang Blenau

  • Forschungszentrum Jülich, Jülich, Germany

    Arnd Baumann

Bibliographic Information

  • Book Title: Serotonin Receptor Technologies

  • Editors: Wolfgang Blenau, Arnd Baumann

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-2187-4

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-2186-7Published: 06 December 2014

  • Softcover ISBN: 978-1-4939-5562-6Published: 23 August 2016

  • eBook ISBN: 978-1-4939-2187-4Published: 05 December 2014

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XII, 245

  • Number of Illustrations: 16 b/w illustrations, 35 illustrations in colour

  • Topics: Neurosciences, Neurochemistry

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access