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Cancer Epigenetics

Risk Assessment, Diagnosis, Treatment, and Prognosis

  • Book
  • © 2015

Overview

Editors:
  1. Mukesh Verma

    1. National Institutes of Health, Rockville, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge techniques in cancer epigenetic research
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1238)

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Table of contents (41 protocols)

  1. Front Matter

    Pages i-xvi
    Download chapter PDF

  2. Background: Epigenetic Mechanism

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Cancer Epigenetics: An Introduction

      • Rajnee Kanwal, Karishma Gupta, Sanjay Gupta
      Pages 3-25

    3. Community Resources and Technologies Developed Through the NIH Roadmap Epigenomics Program

      • John S. Satterlee, Andrea Beckel-Mitchener, Kim McAllister, Dena C. Procaccini, Joni L. Rutter, Frederick L. Tyson et al.
      Pages 27-49

    4. Epigenome-Wide Association Studies (EWAS): Past, Present, and Future

      • James M. Flanagan
      Pages 51-63

    5. Epigenetic Biomarkers in Liver Cancer

      • Krishna K. Banaudha, Mukesh Verma
      Pages 65-76

  3. Cancer Specific Type Epigenetic Changes

    1. Front Matter

      Pages 77-77
      Download chapter PDF

    2. Cancer Type-Specific Epigenetic Changes: Gastric Cancer

      • Danielle Queiroz Calcagno, Marília de Arruda Cardoso Smith, Rommel Rodriguez Burbano
      Pages 79-101

    3. Beyond the Island: Epigenetic Biomarkers of Colorectal and Prostate Cancer

      • Andrea J. Savio, Bharati Bapat
      Pages 103-124

    4. Prostate Cancer Epigenome

      • Swathi Chinaranagari, Pankaj Sharma, Nathan J. Bowen, Jaideep Chaudhary
      Pages 125-140

    5. CpG Island Hypermethylation as a Biomarker for the Early Detection of Lung Cancer

      • Yujin Kim, Duk-Hwan Kim
      Pages 141-171

    6. Analysis of DNA Methylation in Pancreatic Cancer: An Update

      • Christian Pilarsky, Robert Grützmann
      Pages 173-181

    7. Epigenetics of Urothelial Carcinoma

      • Wolfgang A. Schulz, Evangelia A. Koutsogiannouli, Günter Niegisch, Michèle J. Hoffmann
      Pages 183-215

    8. Epigenetics of Prostate Cancer

      • Tawnya C. McKee, James V. Tricoli
      Pages 217-234

    9. Methylation Profile Landscape in Mesothelioma: Possible Implications in Early Detection, Disease Progression, and Therapeutic Options

      • Xinbo Zhang, Naimei Tang, Arun K. Rishi, Harvey I. Pass, Anil Wali
      Pages 235-247

  4. Methods and Technologies Used for Detecting Epigenetic Changes

    1. Front Matter

      Pages 249-249
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    2. Techniques to Access Histone Modifications and Variants in Cancer

      • Monica Tyagi, Shafqat A. Khan, Saikat Bhattacharya, Divya Reddy, Ajit K. Sharma, Bharat Khade et al.
      Pages 251-272

    3. Single Base Resolution Analysis of 5-Methylcytosine and 5-Hydroxymethylcytosine by RRBS and TAB-RRBS

      • Maria A. Hahn, Arthur X. Li, Xiwei Wu, Gerd P. Pfeifer
      Pages 273-287

    4. Quantitative DNA Methylation Analysis for Epigenotyping of Colorectal Cancer

      • Atsushi Kaneda, Koichi Yagi
      Pages 289-299

    5. Histone Modifications Associated with Cancer Cell Migration and Invasion

      • Miki Hieda, Nariaki Matsuura, Hiroshi Kimura
      Pages 301-317
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Keywords

About this book

This volume shares technologies that detect common epigenetic changes which are very important in the early detection, progression, and prognosis of cancer as well as the design of new therapeutic tools against cancer cells. Beginning with a bit of background on epigenetic mechanisms, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis continues with cancer specific type epigenetic change, methods and technologies used for detecting epigenetic changes, factors that influence epigenetic changes in cancer, as well as a final section on future directions in the field. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detailed implementation advice that guarantees easily reproducible results.

Comprehensive and practical, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis provides the most up-to-date knowledge of epigenetics and its implication in cancer prevention by risk assessment and screening and cancer control by treatment.

Editors and Affiliations

  • National Institutes of Health, Rockville, USA

    Mukesh Verma

Bibliographic Information

  • Book Title: Cancer Epigenetics

  • Book Subtitle: Risk Assessment, Diagnosis, Treatment, and Prognosis

  • Editors: Mukesh Verma

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-1804-1

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-1803-4Published: 25 November 2014

  • Softcover ISBN: 978-1-4939-4894-9Published: 23 August 2016

  • eBook ISBN: 978-1-4939-1804-1Published: 24 November 2014

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XVI, 804

  • Number of Illustrations: 42 b/w illustrations, 31 illustrations in colour

  • Topics: Cancer Research, Gene Expression

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