Mass Spectrometry Imaging of Small Molecules

This  volume presents new developments in the field of mass spectrometry imaging, covering imaging, software,  data analysis, new instrumentations, and new methodological approaches. Chapters provide detailed operational instructions from sample preparation to method selection, from comparative quantification to structural identification and from data collection to visualization of small molecule mapping in complex samples. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge, Mass Spectrometry Imaging of Small Molecules aims to  to bring the rapidly maturing methods of metabolic imaging to life science researchers and to minimize technical intimidation in adapting new technological platforms in biological research.

• MALDI-MS
• biological metabolomes
• mass spectrometry
• mass spectrometry imaging
• molecular imaging
• Biological Microscopy

“The purpose is to detail the rapidly maturing methods of metabolic imaging and to minimize technical challenges in adapting new technological platforms in biological research. These are quite worthy objectives that the book meets. The intended audience is life science researchers. The book also will be quite useful for students and scientists interested in learning more about mass spectrometry imaging of small molecules.” (Omer Iqbal, Doody’s Book Reviews, September, 2015)

• Department of Chemistry, North Carolina State University, Raleigh, USA

  Lin He

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