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Handbook of Antimicrobial Resistance

  • Reference work
  • © 2017

Overview

Editors:
  1. Matthias Gotte

    1. McGill University, Montreal, Canada

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  2. Albert Berghuis

    1. Department of Microbiology and Immunology, McGill University, Montreal, Canada

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  3. Greg Matlashewski

    1. Department of Microbiology and Immunology, McGill University, Montreal, Canada

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  4. Mark A. Wainberg

    1. Department of Microbiology and Immunology, McGill University, Montreal, Canada

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  5. Donald Sheppard

    1. Department of Microbiology and Immunology, McGill University, Montreal, Canada

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  • Presents a key, comprehensive study of antimicrobial resistance
  • Provides a timely working tool for those dealing with increasing instances of antimicrobial resistance
  • Supports easy access to information through structured explanations
  • Includes supplementary material: sn.pub/extras

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Table of contents (24 entries)

  1. Front Matter

    Pages i-xvii
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  2. Virology

    1. Front Matter

      Pages 1-1
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    2. HBV Therapy and the Problem of Drug Resistance

      • A. J. Thompson, S. A. Locarnini
      Pages 3-20

    3. Protease Inhibitor Resistance

      • Johannes Vermehren, Christoph Welsch, Christoph Sarrazin
      Pages 21-40

    4. Contribution of APOBEC3-Driven Mutagenesis to HIV Evolution and HIV Drug Resistance

      • Marsha Dillon-White, Viviana Simon
      Pages 41-57

    5. Resistance to Cyclophilin Inhibitors

      • Philippe Gallay
      Pages 59-85

    6. Antiviral Drug Resistance in Herpesviruses

      • Jocelyne Piret, Emilien Drouot, Guy Boivin
      Pages 87-122

    7. Quasispecies and Drug Resistance

      • Celia Perales, Ana M. Ortega-Prieto, Nathan M. Beach, Julie Sheldon, Luis Menéndez-Arias, Esteban Domingo
      Pages 123-147

    8. Substrate-Envelope-Guided Design of Drugs with a High Barrier to the Evolution of Resistance

      • AyÅŸegül Özen, Celia A. Schiffer
      Pages 149-173

  3. Bacteriology

    1. Front Matter

      Pages 175-175
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    2. The Mechanisms of Resistance to β-Lactam Antibiotics

      • Dustin T. King, Solmaz Sobhanifar, Natalie C. J. Strynadka
      Pages 177-201

    3. Antibiotic Resistance and Tolerance in Bacterial Biofilms

      • Geoffrey McKay, Dao Nguyen
      Pages 203-229

    4. Strategies for Circumventing Bacterial Resistance Mechanisms

      • Jed F. Fisher, Jarrod W. Johnson, Shahriar Mobashery
      Pages 231-261

    5. Drug-Resistant Tuberculosis

      • Faiz Ahmad Khan, Greg Fox, Dick Menzies
      Pages 263-286

  4. Parasitology

    1. Front Matter

      Pages 287-287
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    2. The Biochemistry of Quinoline Antimalarial Drug Resistance

      • Paul S. Callaghan, Paul D. Roepe
      Pages 289-311

    3. Drug Resistance in Leishmania

      • Danielle Légaré, Marc Ouellette
      Pages 313-341

  5. Mycology

    1. Front Matter

      Pages 343-343
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    2. Microevolution of Antifungal Drug Resistance

      • Leah E. Cowen
      Pages 345-368

    3. The Role of Biofilm Matrix in Mediating Antifungal Resistance

      • Jeniel E. Nett, David Andes
      Pages 369-384
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Keywords

About this book

This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.​

Editors and Affiliations

  • McGill University, Montreal, Canada

    Matthias Gotte

  • Department of Microbiology and Immunology, McGill University, Montreal, Canada

    Albert Berghuis, Greg Matlashewski, Mark A. Wainberg, Donald Sheppard

About the editors

Matthias Gotte, Department of Medical Microbiology and Immunology, University of Alberta, Canada

Albert M. Berguis, Department of Biochemistry, McGill University, Canada

Greg Matlashewski, Department of Microbiology and Immunology, McGill University, Canada

Donald Sheppard, Department of Microbiology and Immunology, McGill University, Canada

Mark A. Wainberg, Department of Microbiology and Immunology, McGill University, Canada

Bibliographic Information

  • Book Title: Handbook of Antimicrobial Resistance

  • Editors: Matthias Gotte, Albert Berghuis, Greg Matlashewski, Mark A. Wainberg, Donald Sheppard

  • DOI: https://doi.org/10.1007/978-1-4939-0694-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Reference Module Biomedical and Life Sciences

  • Copyright Information: Springer Science+Business Media New York 2017

  • Hardcover ISBN: 978-1-4939-0693-2

  • eBook ISBN: 978-1-4939-0694-9

  • Edition Number: 1

  • Number of Pages: XV, 606

  • Number of Illustrations: 31 b/w illustrations, 42 illustrations in colour

  • Topics: Drug Resistance

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