Editors:
- Features extensive updates to the original edition and several new chapters
- Presents a comprehensive overview of different mechanisms of immune dysfunction
- Discusses a number of new mechanisms that have never been discussed in a monograph report including: T-cell inhibitory molecules and regulatory tolergenic DCs
- Includes supplementary material: sn.pub/extras
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Table of contents (16 chapters)
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Front Matter
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Back Matter
About this book
Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs.
The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.
Editors and Affiliations
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Translational Tumor Immunology, The Wistar Institute, Philadelphia, USA
Dmitry I. Gabrilovich
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N Potomac, USA
Arthur Andrew Hurwitz
Bibliographic Information
Book Title: Tumor-Induced Immune Suppression
Book Subtitle: Mechanisms and Therapeutic Reversal
Editors: Dmitry I. Gabrilovich, Arthur Andrew Hurwitz
DOI: https://doi.org/10.1007/978-1-4899-8056-4
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media, LLC 2014
Hardcover ISBN: 978-1-4899-8055-7
Softcover ISBN: 978-1-4939-5051-5
eBook ISBN: 978-1-4899-8056-4
Edition Number: 2
Number of Pages: XIV, 464
Number of Illustrations: 4 b/w illustrations, 34 illustrations in colour
Topics: Cancer Research, Immunology, Medical Microbiology, Cell Biology, Human Genetics, Developmental Biology