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Birkhäuser

The Search for Antiviral Drugs

Case Histories from Concept to Clinic

  • Book
  • © 1993

Overview

Editors:
  1. Julian Adams

    1. Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Vincent J. Merluzzi

    1. Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Introduction: The First Effective Antiviral

    • Herbert E. Kaufman
    Pages 1-21

  3. Discovery and Development of Zidovudine as the Cornerstone of Therapy to Control Human Immunodeficiency Virus Infection

    • Kathryn H. Pattishall
    Pages 23-43

  4. Discovery of Nevirapine, a Nonnucleoside Inhibitor of HIV-1 Reverse Transcriptase

    • Julian Adams, Vincent J. Merluzzi
    Pages 45-70

  5. Discovery of TIBO, a New Family of HIV-1-Specific Reverse Transcriptase Inhibitors

    • Rudi Pauwels
    Pages 71-104

  6. Discovery and Development of 2-Pyridinone HIV-1 Reverse Transcriptase Inhibitors

    • Mark E. Goldman
    Pages 105-127

  7. Discovery and Development of the HIV Proteinase Inhibitor Ro 31-8959

    • Noel A. Roberts, Sally Redshaw
    Pages 129-151

  8. A New Approach to Antiviral Chemotherapy: Intervention in Viral Gene Expression by HIV Tat Antagonists

    • Ming-Chu Hsu, Steve Tam
    Pages 153-177

  9. Discovery of Pirodavir, a Broad-Spectrum Inhibitor of Rhinoviruses

    • Koen Andries
    Pages 179-209

  10. sICAM-1 as a Receptor Antagonist for Rhinoviruses: A Model System of Adhesion Molecules as Cell Receptors for Viruses

    • Steven D. Marlin
    Pages 211-223

  11. Inactivation of Herpes Simplex Virus Ribonucleotide Reductase by Subunit Association Inhibitors: A Potential Antiviral Strategy

    • Michel Liuzzi, Robert Déziel
    Pages 225-238

  12. Back Matter

    Pages 239-240
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Keywords

Editors and Affiliations

  • Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, USA

    Julian Adams, Vincent J. Merluzzi

Bibliographic Information

  • Book Title: The Search for Antiviral Drugs

  • Book Subtitle: Case Histories from Concept to Clinic

  • Editors: Julian Adams, Vincent J. Merluzzi

  • DOI: https://doi.org/10.1007/978-1-4899-6718-3

  • Publisher: Birkhäuser Boston, MA

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1993

  • Softcover ISBN: 978-1-4899-6720-6Published: 02 October 2013

  • eBook ISBN: 978-1-4899-6718-3Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XIII, 240

  • Number of Illustrations: 40 b/w illustrations

  • Topics: Science, Humanities and Social Sciences, multidisciplinary

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