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Mechanisms of Physical and Emotional Stress

  • Book
  • © 1988

Overview

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 245)

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Table of contents (38 chapters)

  1. Introduction

  2. Basic Mechanisms of the Stress Response

  3. Stress and Immunity

Keywords

About this book

It has been over 50 years since Hans Selye formulated his concept of stress. This came after the isolation of epinephrine and norepinephrine and after the sympathetic system was associated with Walter Cannon's "fight or flight" response. The intervening years have witnessed a number of dis­ coveries that have furthered our understanding of the mechanisms of the stress response. The isolation, identification and manufacture of gluco­ corticoids, the identification and synthesis of ACTH and vasopressin, and the demonstration of hypothalamic regulation of ACTH secretion were pivotal discoveries. The recent identification and synthesis of CRR by Willie Vale and his colleagues gave new impetus to stress research. Several new concepts of stress have developed as a result of advances in bench research. These include the concept of an integrated "stress sys­ tem", the realization that there are bi-directional effects between stress and the immune system, the suggestion that a number of common psychiatric disorders represent dysregulation of systems responding to stress, and the epidemiologic association of stress with the major scourges of humanity.

Editors and Affiliations

  • National Institute of Health, Bethesda, USA

    George P. Chrousos, D. Lynn Loriaux, Philip W. Gold

Bibliographic Information

  • Book Title: Mechanisms of Physical and Emotional Stress

  • Editors: George P. Chrousos, D. Lynn Loriaux, Philip W. Gold

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4899-2064-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1988

  • Hardcover ISBN: 978-0-306-43017-6Published: 01 January 1989

  • Softcover ISBN: 978-1-4899-2066-9Published: 18 July 2013

  • eBook ISBN: 978-1-4899-2064-5Published: 11 November 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 530

  • Number of Illustrations: 40 b/w illustrations

  • Topics: Human Physiology

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