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Muscle, Matrix, and Bladder Function

  • Book
  • © 1995

Overview

Editors:
  1. Stephen A. Zderic

    1. School of Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 385)

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Table of contents (34 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. The Clinical Relevance of Basic Science: A Surgeon’s Perspective

    • John W. Duckett
    Pages 1-2

  3. Bladder Outlet Obstruction — An Overview

    • Alan J. Wein
    Pages 3-5

  4. Bladder Function in Experimental Outlet Obstruction: Pharmacologic Responses to Alterations in Innervation, Energetics, Calcium Mobilization, and Genetics

    • Robert M. Levin, Niels Haugaard, Sheila S. Levin, Ralph Buttyan, Min-Wei Chen, Frederick C. Monson et al.
    Pages 7-19

  5. Electrical Properties of Obstructed Guinea Pig Bladder

    • Jacek L. Mostwin, Narihito Seki Omer Karim, Gommert van Koeveringe
    Pages 21-28

  6. Metabolism of Detrusor Smooth Muscle in Normal and Obstructed Urinary Bladder

    • Bengt Uvelius, Anders Arner
    Pages 29-39

  7. The Neuronal Response to Bladder Outlet Obstruction, a Role for NGF

    • Mary C. Dupont, Katarina Persson, John Spitsbergen, Jeremy B. Tuttle, William D. Steers
    Pages 41-54

  8. Contractile Proteins and Their Response to Bladder Outlet Obstruction

    • Samuel Chacko, Penelope A. Longhurst
    Pages 55-63

  9. Molecular Aspects of Bladder Outlet Obstruction

    • Victor K. Lin, John D. McConnell
    Pages 65-74

  10. Bladder Outlet Obstruction — Discussion

    • Stephen A. Zderic
    Pages 75-79

  11. Developmental Physiology-Overview

    • William C. de Groat
    Pages 81-83

  12. Fetal Lower Urinary Tract Physiology: In Vivo Studies

    • Robert A. Mevorach, Barry A. Kogan
    Pages 85-91

  13. Fetal Bovine Compliance Changes

    • Laurence Baskin, Dave Meaney, Adam Landsman, Serban Constantinescu, Edward Macarak
    Pages 93-104

  14. Developmental Aspects of Excitation Contraction Coupling in Urinary Bladder Smooth Muscle

    • Stephen A. Zderic, Chaoliang Gong, Joseph Hypolite, Robert M. Levin
    Pages 105-115

  15. Congenital Bladder Obstruction: Research Strategies and Directions

    • Craig A. Peters
    Pages 117-130

  16. Developmental Bladder Physiology — Discussion

    • Stephen A. Zderic
    Pages 131-139

  17. Extracellular Matrix Update — Overview

    • Gary Striker
    Pages 141-142

  18. Is Collagen Remodeling Associated with Bladder Obstruction?

    • H. Paul Ehrlich
    Pages 143-149

  19. Regulation of Matrix Metalloproteinases during Extracellular Matrix Turnover

    • Marta L. Corcoran, David E. Kleiner Jr., William G. Stetler-Stevenson
    Pages 151-159

  20. Elastic Fibers and Their Role in Bladder Extracellular Matrix

    • Joel Rosenbloom, Harry Koo, Pamela S. Howard, Robert Mecham, Edward J. Macarak
    Pages 161-172
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About this book

This conference and monograph were the result of many collective efforts. The whole concept was formulated one early Wednesday morning at our weekly research meeting at Children's Hospital in our division of urology. We have been most fortunate to have a close collaboration with Bob Levin, Ed Macarak, and Pam Howard who have helped steer the course of our division's growing interest in basic science. At our weekly meetings our laboratory fellow will summarize their current work. Other ongoing areas of investigation in our labs and elsewhere are discussed. We have always made an effort to try and understand what other groups are doing who are working in the area of bladder smooth muscle research. It occurred to us that the best way to really know what everyone working in this field was doing would be to sponsor a 2-day meeting where we could all gather to discuss our ongoing work. A major limitation of the annual meeting of the American Urologic Association or the urology section of the American Academy of Pediatrics is that the scientfic sessions are limited as these are meant to be primarily clinical meetings (as they should be). For this reason the idea of a meeting devoted solely to research about the urinary bladder had great appeal. In addition to allowing for longer presentations than the standard 5 to 7 minutes, every effort would be made to encourage a dialogue amongst the presenters and the audience.

Editors and Affiliations

  • School of Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA

    Stephen A. Zderic

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