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The Coronaviridae

  • Book
  • © 1995

Overview

Editors:
  1. Stuart G. Siddell

    1. Institute of Virology, University of Würzburg, Würzburg, Germany

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Part of the book series: The Viruses (VIRS)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xviii
    Download chapter PDF

  2. The Coronaviridae

    • Stuart G. Siddell
    Pages 1-10

  3. Coronavirus Replication, Transcription, and RNA Recombination

    • Robbert G. van der Most, Willy J. M. Spaan
    Pages 11-31

  4. Coronavirus Gene Expression

    • Willem Luytjes
    Pages 33-54

  5. Coronavirus Receptors

    • Kathryn V. Holmes, Susan R. Compton
    Pages 55-71

  6. The Coronavirus Surface Glycoprotein

    • David Cavanagh
    Pages 73-113

  7. The Coronavirus Membrane Glycoprotein

    • Peter J. M. Rottier
    Pages 115-139

  8. The Coronavirus Nucleocapsid Protein

    • Hubert Laude, Paul S. Masters
    Pages 141-163

  9. The Coronavirus Hemagglutinin Esterase Glycoprotein

    • David A. Brian, Brenda G. Hogue, Thomas E. Kienzle
    Pages 165-179

  10. The Small-Membrane Protein

    • Stuart G. Siddell
    Pages 181-189

  11. The Coronavirus Nonstructural Proteins

    • T. D. K. Brown, I. Brierley
    Pages 191-217

  12. The Molecular Biology of Toroviruses

    • Eric J. Snijder, Marian C. Horzinek
    Pages 219-238

  13. The Coronaviruslike Superfamily

    • Eric J. Snijder, Willy J. M. Spaan
    Pages 239-255

  14. Pathogenesis and Diseases of the Central Nervous System Caused by Murine Coronaviruses

    • Samuel Dales, Robert Anderson
    Pages 257-292

  15. Feline Infectious Peritonitis

    • Raoul J. de Groot, Marian C. Horzinek
    Pages 293-315

  16. Epidemiology of Infectious Bronchitis Virus

    • Jane K. A. Cook, A. P. A. Mockett
    Pages 317-335

  17. Molecular Basis of Transmissible Gastroenteritis Virus Epidemiology

    • Luis Enjuanes, Bernard A. M. van der Zeijst
    Pages 337-376

  18. Pathogenesis of the Porcine Coronaviruses

    • David J. Garwes
    Pages 377-388

  19. Human Coronavirus Infections

    • Steven H. Myint
    Pages 389-401

  20. The Pathogenesis of Torovirus Infections in Animals and Humans

    • Marion Koopmans, Marian C. Horzinek
    Pages 403-413
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Keywords

About this book

Coronaviruses were recognized as a group of enveloped, RNA viruses in 1968 and accepted by the International Committee on the Taxonomy of Viruses as a separate family, the Coronaviridae, in 1975. By 1978, it had become evident that the coronavirus genomic RNA was infectious (i. e. , positive strand), and by 1983, at least the framework of the coronavirus replication strategy had been per­ ceived. Subsequently, with the application of recombinant DNA techniques, there have been remarkable advances in our understanding of the molecular biology of coronaviruses, and a mass of structural data concerning coronavirus genomes, mRNAs, and pro teins now exists. More recently, attention has been focused on the role of essential and accessory gene products in the coronavirus replication cyde and a molecular analysis of the structure-function relation­ ships of coronavirus proteins. Nevertheless, there are still large gaps in our knowledge, for instance, in areas such as the genesis of coronavirus subgenomic mRNAs or the function of the coronavirus RNA-dependent RNA polymerase. The diseases caused by coronaviruses have been known for much longer than the agents themselves. Possibly the first coronavirus-related disease to be recorded was feline infectious peritonitis, as early as 1912. The diseases associ­ ated with infectious bronchitis virus, transmissible gastroenteritis virus, and murine hepatitis virus were all well known before 1950.

Editors and Affiliations

  • Institute of Virology, University of Würzburg, Würzburg, Germany

    Stuart G. Siddell

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