Overview
- Editors:
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Hans Erik Rugstad
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Department of Clinical Pharmacology, The National Hospital, University of Oslo, Oslo 1, Norway
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Liv Endresen
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Institute of Clinical Biochemistry, The National Hospital, University of Oslo, Oslo 1, Norway
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Øystein Førre
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Oslo Sanitetsforening Rheumatism Hospital, Oslo 1, Norway
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Table of contents (31 chapters)
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Immunology and Pathogenetic Mechanisms
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- Kristian Waalen, Øystein Førre
Pages 15-29
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- Øystein Førre, Kristian Waalen, Jens Kjeldsen-Kragh, Dag Sørskaar, Ove J. Mellbye, Jacob B. Natvig
Pages 31-44
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- Jens Kjeldsen-Kragh, Alison Quayle, Catherine Kalvenes, Øystein Førre
Pages 45-58
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- Dag Sørskaar, Øystein Førre
Pages 59-69
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Pharmacology and General Therapeutic Principles of Immunomodulating Drugs
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Front Matter
Pages 101-101
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- Bruce W. Kirkham, Gabriel S. Panayi
Pages 103-121
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- A. M. Denman, D. J. Denman, R. G. Palmer
Pages 139-158
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- Gilles Feutren, Beat von Graffenried
Pages 159-173
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- Yejun Zhao, Marie L. Foegh
Pages 175-187
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- Lucienne Chatenoud, Jean-François Bach
Pages 189-203
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About this book
This book incorporates the latest advances in immunopharmacological treatment. One objective has been to provide appropriate bridges between the basic sciences of immunology and pharmacology on the one hand and clinical medicine on the other. A further intention has been to emphasize those advances in immunology and pharmacology that are of clinical importance while retaining those facts that, while not new, remain clinically useful. The immunology section provides the necessary background for immunopharmacologi cal treatment. The chapters on individual cell types include normal surface markers, mode of activation, and activation markers and functions in health and disease. The chapters on pharmacology give comprehensive information on immunosuppressive drugs in regular use today, their biochemical and cellular mechanisms of action, pharmaco kinetics, dosage regimens, therapeutic responses, adverse reactions, and drug interactions and tolerance. In addition, certain therapeutic principles that are still in an experimental phase are described, for example, immunotoxins, thymic hormones, and interleukins. The book presents comprehensive information on various autoimmune diseases, the etiopathogenetic immune mechanisms where these are known, and the current possibilities for immunopharmacological intervention. The specific disease section also covers rare situations, fluctuations in disease patterns, and subgroups of patients and immunophar macological treatment in these situations. Altogether, the book represents a practical textbook for clinicians and advanced students who want to be updated on therapeutic principles with regard to autoimmune diseases and transplantation.
Editors and Affiliations
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Department of Clinical Pharmacology, The National Hospital, University of Oslo, Oslo 1, Norway
Hans Erik Rugstad
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Institute of Clinical Biochemistry, The National Hospital, University of Oslo, Oslo 1, Norway
Liv Endresen
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Oslo Sanitetsforening Rheumatism Hospital, Oslo 1, Norway
Øystein Førre
