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Prostaglandins, Leukotrienes, Lipoxins, and PAF

Mechanism of Action, Molecular Biology, and Clinical Applications

  • Book
  • © 1991

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Editors:
  1. J. Martyn Bailey

    1. The George Washington University Medical Center, USA

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Table of contents (42 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Molecular Biology and Enzymology of Prostaglandins and Leukotrienes

    1. Translational Control of Prostaglandin Synthase by Growth Factors and Glucocorticoids

      • J. Martyn Bailey
      Pages 1-14

    2. Two Types of Arachidonate 12-Lipoxygenase Demonstrated by Enzymological Immunological and Molecular Biological Studies

      • Shozo Yamamoto, Tanihiro Yoshimoto, Natsuo Ueda, Yoshitaka Takahashi, Satoshi Matsuda, Hiroshi Suzuki et al.
      Pages 15-22

    3. A Model for the Transcriptional Regulation of a Mouse PGH Synthase Gene

      • David L. DeWitt, Stacey A. Kraemer, Elizabeth A. Meade
      Pages 23-29

    4. Catalytic Properties and Reaction Mechanism of 5-Lipoxygenase

      • D. Riendeau, D. Denis, J.-P. Falgueyret, M. D. Percival, M. J. Gresser
      Pages 31-37

    5. Cloning, Expression and Site-Directed Mutagenesis of the cDNA for Human Placental NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase

      • Charles Mark Ensor, Hsin-Hsiung Tai
      Pages 39-52

    6. Regulation of Cyclooxygenase Gene Expression in Vascular Endothelial Cells

      • Timothy Hla
      Pages 53-58

    7. Structure-Function Studies and Physiological Roles of Eicosanoids Metabolized by Cytochrome P450 ω-Hydroxylases

      • Bettie Sue S. Masters, Joan E. Clark, Linda J. Roman, Timothy J. McCabe, Christian B. Helm, Eric F. Johnson et al.
      Pages 59-66

    8. Multiple Cyclooxygenases: Cloning of a Mitogen-Inducible Form

      • Daniel L. Simmons, Weilin Xie, Jeffrey G. Chipman, Gary E. Evett
      Pages 67-78

    9. Amino Acids Essential to Catalysis by Prostaglandin Endoperoxide Synthase

      • Teruhiko Shimokawa, William L. Smith
      Pages 79-87

    10. Allene Oxide Biosynthesis and Metabolism

      • Wen-Chao Song, Alan R. Brash
      Pages 89-96

    11. Lipoxygenase, Cyclooxygenase and Leukotriene A4 Hydrolase: Quantitative Polymerase Chain Reaction and Expression Studies

      • Colin D. Funk, Xin-Sheng Chen, Garret A. Fitzgerald
      Pages 97-105

  3. Regulatory Mechanisms in Eicosanoid Release and Metabolism

    1. Annexins and Signal Transduction

      • Reginald O. Morgan, Maria Pilar Fernandez
      Pages 107-122

    2. Structural and Functional Properties of Mammalian Group III Cytosolic Phospholipases A2

      • Margarete Goppelt-Struebe, Wolfgang Rehfeldt
      Pages 123-134

    3. Regulation of Plasma Membrane Phospholipase A2 Activity by Phosphorylation/Dephosphorylation: Is Glucocorticoid Action Mediated by Induction of Protein Phosphatase?

      • U. Zor, N. Reiss
      Pages 135-139

    4. Eicosanoid/Signal Transduction Interactions: Evidence of Two Induced Pathways of Phosphoinositide Biosynthesis by LTB4 in Cultured Human Epidermal Cells

      • Vincent A. Ziboh, Wilson Tang
      Pages 141-151

    5. Prostaglandyl-Inositol Cyclic-Phosphate, A New Second Messenger

      • H. Wasner, H. Lemoine, E. Junger, M. Leßmann, R. Kaufmann
      Pages 153-168

    6. Incorporation of Hydroxyeicosatetraenoic Acids into Phospholipid Signaling Pathways

      • Alain B. Legrand, John A. Lawson, John A. Oates
      Pages 169-175

    7. The Purification of Two Intracellular Phospholipase A2s and the Effects of Phospholipase A2 Activating Protein and Mellitin on Their Activities

      • Marion R. Steiner, John S. Bomalaski, Mike A. Clark
      Pages 177-185

    8. Differential Regulation of Phospholipase A2 Activity and Prostacyclin Synthesis in Rat Vascular Smooth Muscle Cells and Cardiomyocytes

      • Dennis J. Church, Ursula Lang, Anne-Catherine Erbrich, Michel B. Vallotton
      Pages 187-198
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Keywords

Editors and Affiliations

  • The George Washington University Medical Center, USA

    J. Martyn Bailey

Bibliographic Information

  • Book Title: Prostaglandins, Leukotrienes, Lipoxins, and PAF

  • Book Subtitle: Mechanism of Action, Molecular Biology, and Clinical Applications

  • Editors: J. Martyn Bailey

  • Series Title: Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia

  • DOI: https://doi.org/10.1007/978-1-4899-0727-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1991

  • Hardcover ISBN: 978-0-306-44055-7Published: 31 January 1992

  • Softcover ISBN: 978-1-4899-0729-5Published: 01 July 2013

  • eBook ISBN: 978-1-4899-0727-1Published: 29 June 2013

  • Edition Number: 1

  • Number of Pages: XI, 461

  • Topics: Pharmacology/Toxicology, Biochemistry, general

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