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New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

  • Book
  • © 1991

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Editors:
  1. Ali M. Emran

    1. The University of Texas Health Science Center, Houston, USA

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Table of contents (49 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. New Trends in Radiopharmaceutical Synthesis, Quality Assurance and Regulatory Control

    1. Introductory Remarks

      • Ali M. Emran
      Pages 1-2

    2. New Trends in Radiopharmaceutical Synthesis Using Positron Emitters: Quality Control

      • Alfred P. Wolf
      Pages 3-3

    3. A Muscarinic Receptor Ligand: Review of the Chemistry and Applications

      • W. C. Eckelman
      Pages 5-5

    4. Application with Positron Emitting Radioisotopes

      1. Aspects on the Synthesis and Design of 11C-Tracers for PET
        • Bengt LÃ¥ngström, Gunnar Antoni, Yvonne Andersson, Svante Axelsson, Peter Bjurling, Karl-Johan Fasth et al.
        Pages 7-20
      2. Special Problems Associated with the Synthesis of High Specific Activity Carbon-11 Labeled Radiotracers
        • Robert F. Dannals, Hayden T. Ravert, Alan A. Wilson, Henry N. Wagner Jr.
        Pages 21-30
      3. P.E.T. Radiopharmaceuticals Via Reductive Carboxylation
        • Siya Ram
        Pages 31-38
      4. [13N] Labeled Tracers, Synthesis and Applications
        • R. S. Tilbury, A. M. Emran
        Pages 39-51
      5. CU1+Assisted Nucleophilic Exchange Radiohalogenation: Application and Mechanistic Approach
        • J. Mertens, M. Gysemans
        Pages 53-65
      6. Potential Breast Tumor Imaging Agents: Fluorotamoxifen and Derivatives
        • David J. Yang, Ali M. Emran, Wayne Tansey, Kenneth C. Wright, Li-Ren Kuang, Gregg Reger et al.
        Pages 67-77
      7. Fluorinated Azabicycloesters as Muscarinic Receptor Ligands for Application with PET
        • Ali M. Emran
        Pages 79-90
      8. Fluorine-18 Ligands for the in Vivo Study of the Beta Adrenergic Receptor in the Heart and Lung
        • T. J. Tewson, B. M. Kinsey, R. Barber
        Pages 91-95
      9. Design and Radiofluorination of Benzamide Dopamine D2 Receptor Ligands
        • Tomas de Paulis, Danny R. Bingham, Ronald G. Manning, N. Scott Mason, M. Sib Ansari, Dennis E. Schmidt et al.
        Pages 97-107

    5. Application with Radiometais

      1. A Synthetic Porphyrin with High Affinity for Lung Cancer Cells and Inflamed Lymphatic Tissue
        • D. A. Cole, D. C. Moody, L. E. Ellinwood, M. G. Klein, J. A. Mercer-Smith, A. Brumbaugh et al.
        Pages 109-117
      2. Gallium and Copper Radiopharmaceutical Chemistry
        • Mark A. Green
        Pages 119-127
      3. Radiometallating Antibodies and Autoantigenic Peptides
        • Janet A. Mercer-Smith, Jeanette C. Roberts, Dawn Lewis, Dean A. Cole, Sherri L. Newmyer, Louis D. Schulte et al.
        Pages 129-152
      4. Biomedical Use of Arsenic Radioisotopes
        • Ali M. Emran, Dennis R. Phillips
        Pages 153-168
      5. Improved Extraction Efficiency of Gallium-67 after Irradiation of Zinc-68 with Protons
        • T. E. Boothe, E. Tavano, J. Munoz, S. T. Carroll, P. M. Smith
        Pages 169-171
      6. Chemistry and Concept for an Automated 72Se/72As Generator
        • D. R. Phillips, V. T. Hamilton, D. A. Nix, W. A. Taylor, D. J. Jamriska, R. C. Staroski et al.
        Pages 173-182
      7. Radiochemistry of Monoclonal Antibody Labeling
        • Lee C. Washburn
        Pages 183-192
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Keywords

About this book

Marking the 200th National Meeting of the American Chemical Society, The Division of Nuclear Chemistry and Technology hosted a group of about 90 scientists from 15 different countries to discuss the new trends in radiopharmaceutical synthesis, quality assurance and regulatory control. This event took place in Washington, D.C. on August 27-30, 1990. When I first suggested the idea for this symposium, a group of scientists who pioneered the proposed topics offered their help to organize and run such a big task with me. Their names are listed here in appreciation. Thomas E. Boothe Cyclotron Facility, Mt. Sinai Medical Center, Miami Beach, Florida, USA Robert F. Dannals Division of Nuclear Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA Anthony L. Feliu Julich Nuclear Research Center, Julich, Germany Joanna S. Fowler Chemistry Department, Brookhaven National Laboratory, Upton, New York, USA George W. Kabalka Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hank F. Kung Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA James F. Lamb Imagents, Inc., Houston, Texas, USA Harold A. O'Brien, Jr. Los Alamos National Laboratory, Los Alamos, New Mexico, USA Joseph R. Peterson Dept. of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hernan Vera Ruiz International Atomic Energy Agency, Vienna, Austria Roy S. Tilbury University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA In addition, a number of distinguished colleagues have participated in the process of reviewing the manuscripts presented in this volume. Their effort is sincerely acknowledged.

Editors and Affiliations

  • The University of Texas Health Science Center, Houston, USA

    Ali M. Emran

Bibliographic Information

  • Book Title: New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

  • Editors: Ali M. Emran

  • DOI: https://doi.org/10.1007/978-1-4899-0626-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1991

  • Hardcover ISBN: 978-0-306-44035-9Published: 31 January 1992

  • Softcover ISBN: 978-1-4899-0628-1Published: 01 July 2013

  • eBook ISBN: 978-1-4899-0626-7Published: 09 November 2013

  • Edition Number: 1

  • Number of Pages: XI, 520

  • Topics: Pharmacology/Toxicology, Nuclear Medicine, Ultrasound, Organic Chemistry

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