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Enkephalins and Endorphins

Stress and the Immune System

  • Book
  • © 1986

Overview

Editors:
  1. Nicholas P. Plotnikoff

    1. Oral Roberts University, Tulsa, USA

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  2. Robert E. Faith

    1. University of Houston, Houston, USA

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  3. Anthony J. Murgo

    1. West Virginia University, Morgantown, USA

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  4. Robert A. Good

    1. University of South Florida, St. Petersburg, USA

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Enkephalins-Endorphins: Stress and the Immune System

    1. Introduction: Ying-Yang Hypothesis of Immunomodulation

      • N. P. Plotnikoff, A. J. Murgo, R. E. Faith, R. A. Good
      Pages 1-2

  3. Stress and the Immune System

    1. Candidate Opioid Peptides for Interaction with the Immune System

      • Christopher J. Evans, Elizabeth Erdelyi, Jack D. Barchas
      Pages 3-15

    2. Control Mechanisms in the Enzyme Hydrolysis of Adrenal-Released Enkephalins

      • L. Giorgio Roda, Gianna Roscetti, Roberta Possenti, Francesca Venturelli, Fabrizio Vita
      Pages 17-33

    3. Studies of the Endogenous Opioid System in the Human Stress Response

      • Martin R. Cohen, David Pickar, Michel Dubois, Robert M. Cohen
      Pages 35-45

    4. Exercise Stress and Endogenous Opiates

      • Peter Farrell, Anthony Gustafson
      Pages 47-57

    5. Effects of Coping and Noncoping with Stressful Events on the Immune System

      • Wolfgang H. Vogel
      Pages 59-68

    6. Depression, Hormones and Immunity

      • Ziad Kronfol, Janet Schlechte
      Pages 69-80

    7. Endogenous Opioid Systems, Stress, and Cancer

      • Ian S. Zagon, Patricia J. Mclaughlin
      Pages 81-100

    8. Effects of Stress and Morphine on Natural Killer Cell Activity and on Mammary Tumor Development

      • James W. Lewis, Yehuda Shavit, Fredricka C. Martin, Gregory W. Terman, Robert P. Gale, John C. Liebeskind
      Pages 101-108

    9. Endocrine and Immunological Responses to Acute Stress

      • F. Berkenbosch, C. J. Heijnen, G. Croiset, C. Revers, R. E. Ballieux, R. Binnekade et al.
      Pages 109-118

  4. Regulatory Circuits of the Immune, Endocrine and Nervous System

    1. A Complete Regulatory Loop between the Immune and Neuroendocrine Systems Operates Through Common Signal Molecules (Hormones) and Receptors

      • Eric M. Smith, J. Edwin Blalock
      Pages 119-127

    2. Endorphins: A Link Between Personality, Stress, Emotions, Immunity, and Disease ?

      • George S. Solomon, Neil Kay, John E. Morley
      Pages 129-144

    3. Involvement of Non-Opiate Peptides in Psychoneuroimmunological Modulations

      • V. Kluša, R. Muceniece, Š. Svirskis, E. Kukaine, M. Ratkeviča, G. Rosenthal et al.
      Pages 145-157

    4. Regulation of Human Cellular Immune Responses by Glucocorticosteroids

      • George C. Tsokos, James E. Balow
      Pages 159-171

    5. Estrogen-Mediated Immunomodulation

      • Oscar J. Pung, Anne N. Tucker, Michael I. Luster
      Pages 173-187

    6. Effects on the Immune System of Lesioning and Stimulation of the Nervous System: Neuroimmunomodulation

      • Branislav D. Jankovic, Novera Herbert Spector
      Pages 189-220

  5. Effects of Enkephalins/Endorphins and Related Substances on Specific Immune Functions

    1. Enkephalins: Mediators of Stress-Induced Immunomodulation

      • Anthony J. Murgo, Robert E. Faith, Nicholas P. Plotnikoff
      Pages 221-239

    2. Relationship between Lymphokine and Opiatergic Modulation of Lymphocyte Proliferation

      • William L. Farrar
      Pages 241-251

    3. Enkephalins as Molecules of Lymphocyte Activation and Modifiers of the Biological Response

      • Joseph Wybran
      Pages 253-262
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Keywords

About this book

Is this a time for a sleeping giant to rise? We have known since study of the lymphocyte and plasma cells really began in earnest in the early 1940's that the pituitary adrenal axis under intimate control of the hypothalamus could influence immunological functions profoundly. We have also known for at least 20 years in my recollection that female sex hor­ mones can maximize certain immunity functions while male sex hormones tend to suppress many immunological reactions. The thyroid hormones accelerate antibody production while at the same time sp~eding up de­ gradation of antibodies and immunoglobulins and thyroidectomy decreases the rate of antibody production. Further, much evidence has accumulated indicating that the brain, yes even the mind, can influence in significant ways susceptibility to infections, cancers and to development of a variety of autoimmune diseases. More than 20 years ago, my colleagues and I convinced ourselves, if no one else, that hypnosis can exert major in­ fluences on the effector limb of the classical atopic allergic reactions. We showed with Aaron Papermaster that the Prausnitz-Kustner reaction may be greatly inhibited, indeed largely controlled, by post-hypnotic suggestion. And it was not even necessary for us to publish our discovery because scientists in John Humphrey's laboratory at Mill Hill Research Center in London had beaten us to the punch. They described hypnotic control of both the PK reaction and delayed allergic reactions to tuberculin by hypnosis.

Editors and Affiliations

  • Oral Roberts University, Tulsa, USA

    Nicholas P. Plotnikoff

  • University of Houston, Houston, USA

    Robert E. Faith

  • West Virginia University, Morgantown, USA

    Anthony J. Murgo

  • University of South Florida, St. Petersburg, USA

    Robert A. Good

Bibliographic Information

  • Book Title: Enkephalins and Endorphins

  • Book Subtitle: Stress and the Immune System

  • Editors: Nicholas P. Plotnikoff, Robert E. Faith, Anthony J. Murgo, Robert A. Good

  • DOI: https://doi.org/10.1007/978-1-4899-0557-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1986

  • Hardcover ISBN: 978-0-306-42226-3Published: 31 May 1986

  • Softcover ISBN: 978-1-4899-0559-8Published: 02 June 2013

  • eBook ISBN: 978-1-4899-0557-4Published: 29 June 2013

  • Edition Number: 1

  • Number of Pages: X, 448

  • Topics: Neurosciences, Psychotherapy and Counseling

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