Schizophrenia

1. Front Matter

   Pages i-xi

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2. The Concept of Schizophrenia

   • John S. Strauss, William T. Carpenter Jr.

   Pages 1-7

3. An Interactive Developmental Systems Model of Schizophrenia

   • John S. Strauss, William T. Carpenter Jr.

   Pages 9-17

4. Assessment and Diagnosis

   • John S. Strauss, William T. Carpenter Jr.

   Pages 19-42

5. Beyond Diagnostic Criteria

   • John S. Strauss, William T. Carpenter Jr.

   Pages 43-55

6. Prognosis

   • John S. Strauss, William T. Carpenter Jr.

   Pages 57-68

7. The Extent of the Problem

   • John S. Strauss, William T. Carpenter Jr.

   Pages 69-76

8. Etiologies of Schizophrenia

   • John S. Strauss, William T. Carpenter Jr.

   Pages 77-114

9. Etiologies of Schizophrenia

   • John S. Strauss, William T. Carpenter Jr.

   Pages 115-136

10. Treatments

    • John S. Strauss, William T. Carpenter Jr.

    Pages 137-161

11. Treatments

    • John S. Strauss, William T. Carpenter Jr.

    Pages 163-196

12. The Clinical-Legal Interface in Schizophrenia

    • John S. Strauss, William T. Carpenter Jr.

    Pages 197-205

13. In Conclusion

    • John S. Strauss, William T. Carpenter Jr.

    Pages 207-211

14. Back Matter

    Pages 213-220

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When Ifirst read this manuscript, Iexclaimed to a colleague: "This is the most important and clinically relevant book on schizophrenia since Bleuler!" Time has not altered my initial enthusiastic evaluation. Drs. Strauss and Carpenter are among the most distinguished researchers in the field ofschizophrenia,butthey are also clinicians ofgreat experience, breadth, sensitivity, and flexibility. It is from this expertise, as well as theirwide familiarity with the world literature, thattheyhavebeenable to distill the essence of an exceedingly practical and comprehensive approach to the understanding, evaluation, diagnosis, and treatment of schizophrenia. They begin by unequivocally stating the inadequacy and futility of approaching schizophrenia via a single model. Standingalone, neither a biomedical, a social, nor a psychological model can adequately account for the complexities of this illness with regard to etiology, phenomenol­ ogy, course, or optimum treatment. While the advent of psychophar­ macologicalinterventionhas made a profound impact on both individual treatment and the responsive support systems, and is an important aspect ofmosttreatmentplans, to view schizophrenia as a phenothiazine deficiency disease is not only bad science but bad therapeutics. Their conceptualization of an "interactive developmental systems model" provides a framework upon which to build a broad medical approach to schizophrenia. This model relates variables drawn from different systems, interactive with one another, and contributing to a pathogenetic process across time. Within this bio-social-psychological matrix, one can then organize information relative to vulnerability, the manifest illness per se, the course of the disorder, and the multiplicity of factors relative to treatmentplanning.

• Evaluation
• assessment
• diagnosis
• epidemiology
• etiology
• intervention

• Yale University School of Medicine, New Haven, USA

  John S. Strauss

• Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, USA

  William T. Carpenter

Policies and ethics