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Neurodegenerative Diseases

Molecular and Cellular Mechanisms and Therapeutic Advances

  • Book
  • © 1996

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Editors:
  1. Gary Fiskum

    1. The George Washington University Medical Center, USA

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Table of contents (54 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Excitotoxicity and Selective Neuronal Vulnerability

    1. Intracellular Signalling in Glutamate Excitotoxicity

      • Ian J. Reynolds, Kari R. Hoyt, R. James White, Amy K. Stout
      Pages 1-7

    2. Long-Term Expression of Proenkephalin and Prodynorphin in the Rat Brain after Systemic Administration of Kainic Acid — an in Situ Hybridization Study

      • Guoying Bing, Belinda Wilson, Michael McMillian, Zhehui Feng, Qiping Qi, Hyoung-Chum Kim et al.
      Pages 9-18

    3. Modulation of Vesicular Glutamate Release during Anoxia

      • Norman Hershkowitz, Alexander N. Katchman
      Pages 19-27

    4. A Model for the Expression of Different Glutamate Transporter Proteins from a Rat Astrocyte-Type Glutamate Transporter Gene

      • Raymond S. Roginski
      Pages 29-32

    5. Glutamate Transporters: Molecular Mechanisms of Functional Alteration and Role in the Development of Excitotoxic Neuronal Injury

      • Davide Trotti, Niels C. Danbolt, Barbara Lodi Rizzini, Paola Bezzi, Daniela Rossi, Giorgio Racagni et al.
      Pages 33-36

    6. Neurodegenerative Disease and Oxidative Stress: Insights from an Animal Model of Parkinsonism

      • Teresa G. Hastings, Michael J. Zigmond
      Pages 37-46

    7. A Progressive Ballooning of Myelinated, TH-Positive Axons is Produced by MPTP in the Dog

      • James S. Wilson, Blair H. Turner, James H. Baker
      Pages 47-53

    8. HIV-1 Coat Protein GP120 Induces Neuronal Injury to Cultured Dopamine Cells

      • Barbara A. Bennett, Daniel E. Rusyniak, Charlotte K. Hollingsworth
      Pages 55-62

    9. Platelets as Peripheral Model of Glutamate-Related Excitotoxicity in Parkinson’s Disease

      • Carlo Ferrarese, Graziella Bianchi, Marianna Bugiani, Tiziana Cogliati, Maura Frigo, Davide Passoni et al.
      Pages 63-68

    10. Brainstem Motoneuron Cell Groups that die in Amyotrophic Lateral Sclerosis are Rich in the GLT-1 Glutamate Transporter

      • Loreta Medina, Griselle Figueredo-Cardenas, J. D. Rothstein, Anton Reiner
      Pages 69-76

    11. Progressive Neurodegeneration in Rat Brain after Chronic 3-VO or 2-VO

      • J. C. de la Torre, B. A. Pappas, T. Fortin, M. Keyes, C. Davidson
      Pages 77-84

  3. Molecular and Genetic Risk Factors

    1. In Vivo Biology of APP and its Homologues

      • Sangram S. Sisodia, Gopal Thinakaran, Cornelia S. von Koch, Hilda H. Slunt, A. Jane I. Roskams, Cheryl A. Kitt et al.
      Pages 85-90

    2. Lymphocyte Amyloid Precursor Protein mRNA Isoforms in Normal Aging and Alzheimer’s Disease

      • Richard P. Ebstein, Lubov Nemanov, Gregory Lubarski, Marina Dano, Teres Trevis, Amos Korczyn
      Pages 91-95

    3. Differential Regulation of APP Secretion by Apolipoprotein E3 and E4

      • Benjamin Wolozin, Jasna Basaric-Keys, Robert Canter, Yunhua Li, Dudley Strickland, Trey Sunderland
      Pages 97-102

    4. Apolipoprotein E Uptake is Increased by Beta-Amyloid Peptides and Reduced by Blockade of the LDL Receptor

      • Uwe Beffert, Nicole Aumont, Doris Dea, Jean Davignon, Judes Poirier
      Pages 103-108

    5. The Non-Amyloid-β Component of Alzheimer’s Disease Plaque Amyloid: Comparative Analysis Suggests a Normal Function as a Synaptic Plasticizer

      • Julia M. George, David F. Clayton
      Pages 109-112

    6. Mutations of Human Cu, Zn Superoxide Dismutase Expressed in Transgenic Mice Cause Motor Neuron Disease

      • Mark E. Gurney, Arlene Y. Chiu, Mauro C. Dal Canto, John Q. Trojanowski, Virginia M.-Y. Lee
      Pages 113-122

    7. Effect of the Kennedy Mutation of the Androgen Receptor on Gene Expression in Neuroblastoma Cells

      • P. A. Yerramilli-Rao, O. Garofalo, P. N. Leigh, J.-M. Gallo
      Pages 123-131

    8. Glutamate-Promoted Survival in Hippocampal Neurons: A Defect in Mouse Trisomy 16

      • Linda L. Bambrick, Paul J. Yarowsky, Bruce K. Krueger
      Pages 133-139
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Keywords

Editors and Affiliations

  • The George Washington University Medical Center, USA

    Gary Fiskum

Bibliographic Information

  • Book Title: Neurodegenerative Diseases

  • Book Subtitle: Molecular and Cellular Mechanisms and Therapeutic Advances

  • Editors: Gary Fiskum

  • Series Title: Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia

  • DOI: https://doi.org/10.1007/978-1-4899-0209-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1996

  • Hardcover ISBN: 978-0-306-45298-7Published: 30 April 1996

  • Softcover ISBN: 978-1-4899-0211-5Published: 22 June 2013

  • eBook ISBN: 978-1-4899-0209-2Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XII, 482

  • Topics: Biochemistry, general, Neurosciences

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