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Eicosanoids

From Biotechnology to Therapeutic Applications

  • Book
  • © 1996

Overview

Editors:
  1. Gian Carlo Folco

    1. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

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    You can also search for this editor in PubMed   Google Scholar

  2. Bengt Samuelsson

    1. Karolinska Institute, Stockholm, Sweden

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    You can also search for this editor in PubMed   Google Scholar

  3. Jacques Maclouf

    1. Hôpital Lariboisére, Paris, France

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  4. G. P. Velo

    1. University of Verona Medical School, Verona, Italy

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Part of the book series: NATO Science Series A: (NSSA, volume 283)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-ix
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  2. Leukotriene A4 Hydrolase: A Key Enzyme in the Biosynthesis of Leukotriene B4

    • Anders Wetterholm, Martina Blomster, Jesper Z. Haeggström
    Pages 1-12

  3. Lipoxygenases of Mice and Men

    • Colin D. Funk
    Pages 13-20

  4. The Physiological and Therapeutic Significance of Separate Pathways for Prostaglandin Synthesis

    • David L. DeWitt
    Pages 21-36

  5. Assessment of Pharmacological Inhibition of PGH-Synthases in Man

    • P. Patrignani, M. R. Panara, F. Cipollone, G. Santini, M. G. Sciulli, M. T. Rotondo et al.
    Pages 37-44

  6. Metabolism of Eicosanoids in Mammalian Cells

    • Robert C. Murphy
    Pages 45-59

  7. New Approach in Immunometric Assays

    • P. Pradelles, E. Etienne, C. Créminon, Y. Frobert, H. Volland, J. Grassi
    Pages 61-75

  8. Transcellular Biosynthesis of Arachidonic Acid Metabolites: From in Vitro Investigations to in Vivo Reality

    • Jacques Maclouf
    Pages 77-88

  9. Polymorphonuclear-Endothelial Cell Interactions and the Control of Coronary Vasculature

    • Angelo Sala
    Pages 89-97

  10. PGHS-2 Dependent Formation of 8-Epi PGF2α by Human Monocytes

    • Domenico Praticò, Garret A. Fitzgerald
    Pages 99-103

  11. Platelet-Activating Factor Regulates Events at the Vascular Wall

    • Stephen M. Prescott, Thomas M. McIntyre, Guy A. Zimmerman
    Pages 105-109

  12. Studies of Isoprostane Biosynthesis in Man

    • G. Ciabattoni, P. Patrignani, M. R. Panara, A. Greco, F. Cipollone, G. Davi et al.
    Pages 111-115

  13. N-3 Fatty Acids. Antithromboxane Activity. Effects on Redox Status of Blood Cells

    • M. Lagarde, M. Croset, E. Véricel, G. C. Le Breton, A. F. Prigent, C. Calzada
    Pages 117-125

  14. Receptors and Second Messengers for Cys-Leukotrienes

    • S. Nicosia, V. Capra, M. R. Accomazzo, E. Galbiati, D. Ragnini, R. Saponara et al.
    Pages 127-136

  15. Prostanoid Receptors

    • Robert A. Coleman
    Pages 137-154

  16. Microvascular Actions and Interactions of Eicosanoids and Histamine in Inflammation

    • Per Hedqvist, Lennart Lindbom, Henrik Thorlacius, Johan Raud
    Pages 155-163

  17. Leukotriene Antagonists and Synthetase Inhibitors; Clinical Applications in the Treatment of Bronchial Asthma

    • G. C. Folco, C. Buccellati, T. Testa, M. Bolla, A. Sala
    Pages 165-182

  18. PGI2 and Its Analogs: From Pharmacology to Therapeutic Applications

    • S. Nicosia
    Pages 183-193

  19. Leukotriene Synthesis (FLAP) Inhibition: Biochemistry and Pharmacology of Bay X 1005

    • R. Müller-Peddinghaus, R. Kast
    Pages 195-204

  20. Back Matter

    Pages 205-208
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Keywords

Editors and Affiliations

  • Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    Gian Carlo Folco

  • Karolinska Institute, Stockholm, Sweden

    Bengt Samuelsson

  • Hôpital Lariboisére, Paris, France

    Jacques Maclouf

  • University of Verona Medical School, Verona, Italy

    G. P. Velo

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