Skip to main content
SpringerLink
Log in

Metals and Oxidative Damage in Neurological Disorders

  • Book
  • © 1997

Overview

Editors:
  1. James R. Connor

    1. Pennsylvania State University, Hershey, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xxii
    Download chapter PDF

  2. Iron and Neurotransmitter Function in the Brain

    • Yelena Glinka, Michael Gassen, Moussa B. H. Youdim
    Pages 1-22

  3. Evidence for Iron Mismanagement in the Brain in Neurological Disorders

    • James R. Connor
    Pages 23-39

  4. Magnetic Resonance Imaging of Brain Iron

    • George Bartzokis
    Pages 41-56

  5. Neurochemical Roles of Copper as Antioxidant or Prooxidant

    • Joseph R. Prohaska
    Pages 57-75

  6. Manganese Neurotoxicity and Oxidative Damage

    • Michael Aschner
    Pages 77-93

  7. The Role of Zinc in Brain and Nerve Functions

    • Ananda S. Prasad
    Pages 95-111

  8. Delivery of Metals to Brain and the Role of the Blood-Brain Barrier

    • Quentin R. Smith, Olivier Rabin, Elsbeth G. Chikhale
    Pages 113-130

  9. Ferritin

    • J. G. Joshi
    Pages 131-147

  10. Ascorbate

    • George V. Rebec
    Pages 149-173

  11. Vitamin E

    • G. T. Vatassery
    Pages 175-188

  12. Nitric Oxide and Oxidative Damage in the CNS

    • Deborah A. Dawson
    Pages 189-203

  13. Iron and Oxidative Stress in Neonatal Hypoxic-Ischemic Brain Injury Directions for Therapeutic Intervention

    • Charles Palmer
    Pages 205-236

  14. The Role of Oxidative Processes and Metal Ions in Aging and Alzheimer’s Disease

    • Leslie A. Shinobu, M. Flint Beal
    Pages 237-275

  15. Oxidative Stress with Emphasis on the Role of LAMMA in Parkinson’s Disease

    • Paul F. Good, Daniel P. Perl, C. Warren Olanow
    Pages 277-294

  16. Perspectives on the Mechanisms of Familial Amyotrophic Lateral Sclerosis Caused by Mutations in Superoxide Dismutase 1

    • David R. Borchelt, Philip C. Wong, Mark W. Becher, Lucie I. Bruijn, Don W. Cleveland, Neal G. Copeland et al.
    Pages 295-314

  17. Tardive Dyskinesia and Oxidative Stress

    • Jean Lud Cadet
    Pages 315-324

  18. Antioxidant Therapeutic Strategies in CNS Disorders

    • Edward D. Hall
    Pages 325-339

  19. Oxidative Stress-Induced Cell Damage in the CNS

    • Sara J. Robb-Gaspers, James R. Connor
    Pages 341-351

  20. Back Matter

    Pages 353-374
    Download chapter PDF
Back to top

Keywords

About this book

The purpose of this book is to bring together scientists and clinicians interested in oxidative injury in the nervous system but whose approaches to investigation and treatment design vary widely. Indeed the goal of this book is to show that the investiga­ tive approaches and potential therapeutic interventions perhaps do not vary as widely as some may think. I think that the readers of this book will not read it from front to back, but will pick chapters of interest. Thus, the chapters are organized to contain information that is essential to understanding basic aspects of oxidative injury, and thus have some redundancy. However, within the context of each chapter the reader should hopefully find impetus and direction to go on to another chapter. The book is divided into three seetions. The first section contains reviews of metals and their role in generating oxidative injury. lron is considered in three of these chapters because of its relative abundance in the brain and its potency in inducing free radicals. The second section focuses on mechanisms by which the brain attempts to protect itself from oxidative injury. Some of these mechanisms have the potential to be protective in some situations and potentiaIly damaging in others. The third section contains the clinicaI diseases in which oxidative injury is known to contribute to the pathogenic process. This seetion ends with a chapter on antioxidant therapeutic strate­ gies in neurological disorders.

Editors and Affiliations

  • Pennsylvania State University, Hershey, USA

    James R. Connor

Bibliographic Information

  • Book Title: Metals and Oxidative Damage in Neurological Disorders

  • Editors: James R. Connor

  • DOI: https://doi.org/10.1007/978-1-4899-0197-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1997

  • Hardcover ISBN: 978-0-306-45534-6Published: 30 September 1997

  • Softcover ISBN: 978-1-4899-0199-6Published: 04 June 2013

  • eBook ISBN: 978-1-4899-0197-2Published: 29 June 2013

  • Edition Number: 1

  • Number of Pages: XXII, 374

  • Topics: Neurosciences

Publish with us

Policies and ethics

Back to top

Search

Navigation