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Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular

  • Book
  • © 1988

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Editors:
  1. Eric Reid

    1. Guildford Academic Associates, Guildford, UK

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  2. J. D. Robinson

    1. Hoechst UK, Milton Keynes, UK

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    You can also search for this editor in PubMed   Google Scholar

  3. Ian D. Wilson

    1. ICI Pharmaceuticals Division, Macclesfield, UK

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Part of the book series: Methodological Surveys in Biochemistry and Analysis (MSBA, volume 18 A)

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Table of contents (58 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Eicosanoids and Related Analytes

    1. Front Matter

      Pages 1-1
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    2. The Use of HPLC in Studies of the Stereoselective Metabolism of Prostaglandin D2

      • Clive Robinson
      Pages 3-13

    3. Analysis of Eicosanoids by GC-MS/MS

      • J. C. Frölich, K.-H. Marx, H. Bippi, J. Fauler, B. Rosenkranz, U. Förstermann
      Pages 15-21

    4. Quantitative Determination of Several Prostaglandins and Thromboxane B2 in the Isolated Perfused Rat Brain

      • Claudia Weber, Klaus Belsner, Barbara Osikowska-Evers, Inge Luhmann, Michael Höller
      Pages 23-27

    5. Analytical Methods for [3H]-Enisoprost, an Anti-Secretory PGE1 Analogue, and its Metabolites

      • L. A. Allan, A. J. Hawkins, J. Firth, R. D. Brownsill, J. A. Steiner, C. W. Vose
      Pages 29-35

    6. Identification of a New Metabolite of Leukotriene B4 by RP-HPLC and GC-MS Analysis

      • Joachim Fauler, Karl-Heinz Marx, Volkhard Kaever
      Pages 37-41

    7. Radioimmunoassay of Eicosanoids: Its Application in the Development of Anti-Inflammatory and Analgesic Drugs

      • Frank Carey, Duncan Haworth, Robert A. Forder
      Pages 43-50

  5. Notes and Comments Relating to Anti-Inflammatory Drugs

    1. Front Matter

      Pages 127-127
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    2. The Determination of Suprofen in Biological Fluids

      • C. J. Dyde, M. F. Barkworth, K. D. Rehm
      Pages 129-132
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Keywords

About this book

vi as did non-appreciation that % values for bought-in solutions (notably ammonia) may be on a weight basis, not made evident by the manufacturer. Notwithstanding the shortcomings or lateness of some texts, authors are thanked for compiling them amidst other pressures. Elsevier and the American Chemical Society are also thanked, for Figures now reproduced with source acknowledgement. This Editor has generally respected authors' phrasing, whilst shuddering when the term 'incubate' is encountered in a 0° context. He remains a 'diehard' in certain respects, notably in favouring 'M' rather than 'mol/I', and a wt./ml basis for drug concentrations in test samples; he regards 'mmol/l' as a fatuous fashion. Concerning infelicitous abbreviations, a distinction is made between electron­ capture (detector context; 'ECD') and electrochemical ('EC', never 'ECD'); the hallowed GC term 'FID' means free induction decay to NMR practi tione:ts, who may pardon the term 'Fid' as introduced editorially. The convention for ,0C' throughout the book is '0'. Undefined but well-known abbreviations include GC, HPLC and TLC. MS (mass spectrometry), NPD (nitrogen-phosphorus detector), tr (retention time) and RIA (radioimmunoassay) are usually defined in the article concerned, as are the HPLC modes NP (normal-/straight­ phase) and RP (reversed-phase; C-lS and ODS are synonymous), and i.s.

Editors and Affiliations

  • Guildford Academic Associates, Guildford, UK

    Eric Reid

  • Hoechst UK, Milton Keynes, UK

    J. D. Robinson

  • ICI Pharmaceuticals Division, Macclesfield, UK

    Ian D. Wilson

Bibliographic Information

  • Book Title: Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular

  • Editors: Eric Reid, J. D. Robinson, Ian D. Wilson

  • Series Title: Methodological Surveys in Biochemistry and Analysis

  • DOI: https://doi.org/10.1007/978-1-4757-9424-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1988

  • Hardcover ISBN: 978-0-306-42996-5Published: 01 September 1988

  • Softcover ISBN: 978-1-4757-9426-7Published: 23 May 2013

  • eBook ISBN: 978-1-4757-9424-3Published: 21 November 2013

  • Edition Number: 1

  • Number of Pages: XIV, 415

  • Topics: Chemistry/Food Science, general

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