Gangliosides and Neuronal Plasticity

1. Front Matter

   Pages I-XIII

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2. Biochemical and technological aspects

   1. A Review of Mass Spectrometric Techniques in the Structural Analysis of Native and Derivatized Gangliosides

      • H. Egge, J. Peter-Katalinić

      Pages 1-15

   2. Advances in Ganglioside Chemistry

      • Sandro Sonnino, Domenico Acquotti, Günther Kirschner, Giovanni Fronza, Guido Tettamanti

      Pages 17-46

   3. The Solution Conformation of Gangliosides Inferred from HSEA Calculations and High Field NMR Spectroscopy

      • K. Bock

      Pages 47-56

   4. A Novel Disialoganglioside (GD1α) with N-Acetylneuraminyl (α2 → 6)-N-Acetylgalactosamine Linkage in Rat Ascites Hepatoma Cells

      • Takao Taki, Yoshio Hirabayashi, Hidemi Ishikawa, Susumu Ando, Kazuo Kon, Koichi Tanaka et al.

      Pages 57-66

   5. Topographical Distribution of the Gangliosides in the Developing and Adult Human Brain

      • Ivica Kracun, Harald Rösner, Cedomir Cosovic

      Pages 67-76

   6. The Use of Antibodies to Identify Glycosphingolipids and to Localize Them in Tissues

      • Donald M. Marcus

      Pages 77-82

   7. Expression of Ganglioside-Antigens During Neuronal Differentiation Studied by Use of Monoclonal Antibodies

      • H. Rösner, C. J. Willibald, S. Henke-Fahle

      Pages 83-93

3. Functional aspects

   1. Gangliosides as Differential Modulators of Membrane-Bound Protein Kinase Systems

      • Robert K. Yu, James R. Goldenring, John Y. H. Kim, Robert J. DeLorenzo

      Pages 95-104

   2. Membrane Aging of the Brain Synaptosomes with Special Reference to Gangliosides

      • Susumu Ando, Yasukazu Tanaka, Kazuo Kon

      Pages 105-112

   3. Possible Association of Degenerative Motor Neuron Disease (ALS) with Abnormal Ganglioside Metabolism: Abnormal Gangliosides in ALS Spinal Cord and ALS-Like Symptoms in a Unique Partial HexB Deficiency Syndrome

      • G. Dawson, L. W. Hancock, A. L. Horwitz, R. Wollman, N. Cashman, J. Antel

      Pages 113-124

   4. Ultrastructural Localization of Calcium at Synapses and Modulatory Interactions with Gangliosides

      • Hinrich Rahmann, Wolfgang Probst

      Pages 125-135

   5. Involvement of Gangliosides in the Synaptic Transmission in the Hippocampus and Striatum of the Rat Brain

      • A. Wieraszko, W. Seifert

      Pages 137-151

   6. Antibody to Glycolipid in a Patient with IgM Paraproteinemia and Polyradiculoneuropathy

      • Hiroko Baba, Nobuyuki Miyatani, Shuzo Sato, Kyoko Nakamura, Tatsuhiko Yuasa, Tadashi Miyatake

      Pages 153-159

4. Metabolic aspects

   1. Axonal Transport of Gangliosides and Neutral Glycolipids in the Peripheral Nervous System. Identification of Ganglioside Types in Motoneurons of the PNS

      • D. A. Aquino, M. A. Bisby, R. W. Ledeen

      Pages 161-169

   2. Concepts of Ganglioside Metabolism

      • U. Hinrichs, S. Sonderfeld, G. Schwarzmann, E. Conzelmann, K. Sandhoff

      Pages 171-182

   3. Metabolism of Exogenous GM1 and Related Glycolipids in the Rat

      • R. Ghidoni, M. Trinchera, B. Venerando, A. Fiorilli, G. Tettamanti

      Pages 183-200

5. Gangliosides and neuronal plasticity in vitro

   1. Ganglioside-Mediated Modulation of Growth Factor Receptor Function

      • Sen-itiroh Hakomori, Eric Bremer, Yoshio Okada

      Pages 201-214

   2. Neuritic Responses to GM1 Ganglioside in Several in Vitro Systems

      • Silvio Varon, Stephen D. Skaper, Ritsuko Katoh-Semba

      Pages 215-230

   3. Functional Analysis of Ganglioside-Respondable Human Neuroblastoma Cell Lines

      • Y. Nagai, S. Tsuji, J. Nakajima, T. Sasaki

      Pages 231-244

This volume contains the Proceedings of the Meeting "Neuronal plasticity and gangliosides" which was held at Mantova, Italy, on May 29-31, 1985, as a satellite to the Tenth Meeting of the International Society for Neurochemistry, (Riva del Garda, Italy, May 19-24,1985). The Symposium took place in the "Teatro Bibiena", one of the oldest and most beautiful theatres in Italy, known for having been the place for some of the very first performances of W .A. Mozart. The number of registered participants in the Meeting was about 180 including 40 accor:Qpanying persons. The persons invited as Speakers or Chairmen of Colloquia and Workshops were 48. Eighteen countries were represented with the largest contingent coming from Italy, followed by Federal Republic of Germany, The United States, France and Great Britain. The Meeting was based on Colloquia, Workshops, Round Tables and Poster Sessions, with a total of 42 Lectures and 32 Poster presentations.

• Germany
• neurochemistry

• Dipartimento di Chimica e Biochimica Medica, Facoltà di Medicina e Chirurgia, Università di Milano, Milano, Italy

  Guido Tettamanti

• Dept of Neurology and Biochemistry, Albert Einstein College of Medicine, Bronx, USA

  Robert W. Ledeen

• Institut für Organische, Chemie und Biochemie, Universität Bonn, Bonn, Germany

  Konrad Sandhoff

• Dept of Biochemistry, University of Tokyo, Tokyo, Japan

  Yoshitaka Nagai

• Dept of Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan

  Yoshitaka Nagai

• Research Laboratories, Fidia Neurobiological, Abano Terme, Italy

  Gino Toffano

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