Biology of Parasitism

1. Front Matter

   Pages i-xix

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2. Molecular Biology

   1. Import of Nuclear Encoded tRNA into Mitochondria

      • Audra E. Yermovsky-Kammerer, Stephen L. Hajduk

      Pages 1-18

   2. RNA Metabolism in Trypanosomes: Approaches to Unravel pre-mRNA Signals Required for Intron Removal

      • Christian Tschudi, Elisabetta Ullu

      Pages 19-42

   3. Stable Transfection of Plasmodium Berghei: A Crash Course

      • Andrew P. Waters

      Pages 43-72

3. Biochemistry

   1. Malaria Chemotherapy: Paradigms from Pyrimidine Metabolism

      • Pradipsinh K. Rathod

      Pages 73-93

   2. Polyamine and Glutathione Biosynthetic Enzymes from Trypanosoma Brucei and Trypanosoma Cruzi

      • Lisa N. Kinch, Deirdre L. Brekken, Margaret A. Phillips

      Pages 95-119

   3. Acetylcholinesterases of Gastrointestinal Nematodes

      • Murray E. Selkirk, Ayman S. Hussein

      Pages 121-142

4. Cell Biology

   1. Toxoplasma as a Model Apicomplexan Parasite: Biochemistry, Cell Biology, Molecular Genetics, Genomics and Beyond

      • David S. Roos, John A. Darling, Mary G. Reynolds, Kristin M. Hager, Boris Striepen, Jessica C. Kissinger

      Pages 143-167

   2. The Trichomonad Hydrogenosome

      • Sabrina D. Dyall, Patricia J. Johnson

      Pages 169-193

   3. Lysosome Exocytosis and Invasion of Non-Phagocytic Host Cells by Trypanosoma Cruzi

      • Barbara A. Burleigh

      Pages 195-212

   4. Cell Biological Approaches to the Study of Intracellular Pathogens: Motility, Invasion, Secretion and Vesicular Trafficking

      • David G. Russell, Dana G. Mordue, Wandy Beatty, Olivia K. Giddings, Jennie L. Lovett, Andreas Lingnau et al.

      Pages 213-254

5. Immunology

   1. Cytokine Regulation of Filaria: Induced Airway and Corneal Disease

      • Eric Pearlman, Rajeev K. Mehlotra, Musa A. Haxhiu, Laurie R. Hall

      Pages 255-272

   2. Molecular Mechanisms of Granuloma Formation in Schistosomiasis

      • Stephen J. Davies, James H. McKerrow

      Pages 273-289

   3. Experimental Approaches to Studying the Immunology of Parasitic Diseases

      • Edward J. Pearce, Phillip Scott

      Pages 291-318

6. Back Matter

   Pages 319-328

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Biology of Parasitism is based on the Biology of Parasitism Course at the Marine Biological Laboratory in Woods Hole, Massachusetts. Having just celebrated its 20th offering, this Course has distinguished itself as the premier, world-renowned training ground for future generations of parasitologists. The primary goal of the Course is to attract and introduce the very best and most promising young researchers to the many unresolved problems in parasitology and prepare them for their future as independent investigators in the field. The rigorous program combines state-of-the-art laboratory research with a program of visiting lecturers who bring together the most current research in the field. Since at this time there are no academic institutions that have enough depth in parasitology research or teaching faculty to provide up-to-date and state-of-the-art training, the Course has become, and will remain, a global resource for providing intensive education in modern parasitology.
Biology of Parasitism is intended to present a snapshot of the content and spirit of the Biology of Parasitism Course. By presenting a series of chapters that reflect the formal lectures that students receive on a daily basis, as well as the approaches used during the laboratory section of the Course, the editors hope to share some of the science that occurs there. One part of the book presents the experimental component of the Course, in particular the subject matter of the four two-week sessions covering Immunology, Biochemistry, Cell Biology and Molecular Biology of protozoan and helminth parasites. As in the Course, the experimental part is complemented by a number of review-like chapters solicited from the large number of speakers who lecture during the Course.

• Malaria
• Schistosomiasis
• cell
• cell biology
• cytokine
• diseases
• genetics
• immunology
• molecular biology
• parasite
• parasites
• parasitology
• infectious diseases

• Department of Internal Medicine, Yale University School of Medicine, New Haven, USA

  Christian Tschudi

• Department of Microbiology and Immunology, Cornell University, Ithaca, USA

  Edward J. Pearce

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