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Breast Cancer Immunodiagnosis and Immunotherapy

  • Book
  • © 1989

Overview

Editors:
  1. Roberto L. Ceriani

    1. John Muir Cancer and Aging Research Institute, Walnut Creek, USA

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xi
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  2. Session I

    1. Front Matter

      Pages 1-1
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    2. The Potential of Synthetic Tumor-Associated Glycoconjugates (S-TAGs) for Generating Monoclonal Antibodies for Breast Cancer Imaging and for Specific Immunotherapy

      • Grant MacLean, Alexander McEwan, Eleanor Mackie, Peter Fung, Carina Henningsson, Rao Koganty et al.
      Pages 3-11

    3. Extracellular Keratins: An Update

      • Robert D. Cardiff, Shoichiro Taniuchi, Daer He
      Pages 13-17

    4. Preclinical Evaluation of MoAbs Mc5 and BrEl

      • Roberto L. Ceriani, Hector Battifora, Edward W. Blank, Jerry A. Peterson, Cindy Zoellner
      Pages 19-32

    5. The Use of Human Monoclonal Antibodies to Identify and Isolate Breast Tumor Associated Antigens

      • Anthony J. Strelkauskas, Paul H. Aldenderfer
      Pages 33-44

    6. Clinical and Molecular Investigations of the DF3 Breast Cancer-Associated Antigen

      • Daniel F. Hayes, Miyako Abe, Javed Siddiqui, Carlo Tondini, Donald W. Kufe
      Pages 45-53

    7. An Assay for Cryptic Tumor Antigens in Sera of Women with Breast Cancer

      • R. Kinders, J. Slota, J. Patrick, C. Plate, I. Kafer, W. Caminiti et al.
      Pages 55-67

  3. Session II

    1. Front Matter

      Pages 69-69
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    2. Biosynthesis of the Cell Surface Sialomucin from Ascites 13762 Rat Mammary Adenocarcinoma Cells: Intracellular Maturation

      • Steven R. Hull, Julie Spielman, Kermit L. Carraway
      Pages 71-79

    3. Epithelial Mucin Antibodies and Their Epitopes: Core Protein Epitopes of a Polymorphic Epithelial Mucin (PEM)

      • Joyce Taylor-Papadimitriou, Joy Burchell, Sandra Gendler, Martina Boshell, Trevor Duhig
      Pages 81-93

    4. Cell Heterogeneity and Complexity of Breast Epithelial Surface Antigens Expression and Moab Therapy

      • Jerry A. Peterson, Edward Blank, Cindy Zoellner, Sean Enloe, Garrett Walkup, Roberto L. Ceriani
      Pages 95-103

    5. The Oncogenic Potential of Membrane Receptor Proteins Encoded by Members of the Human erbB Proto-Oncogene Family

      • Matthias H. Kraus
      Pages 105-115

  4. Session III

    1. Front Matter

      Pages 117-117
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    2. Estrogen and Progesterone Receptor Analysis and Action in Breast Cancer

      • Geoffrey L. Greene, Paul Gilna, Peter Kushner
      Pages 119-129

    3. Monoclonal Antibodies Against Steroid Receptors and Steroid-Induced Proteins

      • Martine Perrot-Applanat, Jean-François Prud’homme, Mai-Thu Vu Hai, André Jolivet, Frédéric Lorenzo, Edwin Milgrom
      Pages 131-139

    4. Ten Year Survival Patterns in Primary Breast Cancers Compared to Hormone Receptor Antigen Detection by Monoclonal Antibodies

      • Petra Kiene, Laura Kinsel, John Konrath, Geoffrey Greene, George Leight, Edwin Cox et al.
      Pages 141-147

    5. Significance of Steroid Receptor Immunoassay in Breast Cancer

      • Edward J. Keenan, Debra Corbin
      Pages 149-159

    6. H23 Monoclonal Antibody Recognizes a Breast Tumor Associated Antigen: Clinical and Molecular Studies

      • I. Tsarfaty, S. Chaitchik, M. Hareuveni, J. Horev, A. Hizi, D. H. Wreschner et al.
      Pages 161-169

    7. Complementation of Monoclonal Antibodies DF3 and B72. 3 in Reactivity to Breast Cancer

      • Noriaki Ohuchi, Minoru Akimoto, Shozo Mori, Donald W. Kufe, Jeffrey Schlom
      Pages 171-181
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Keywords

About this book

The convening of the 3rd International Workshop on Monoclonal Antibodies and Breast Cancer had the character of a self-search exercise. After almost a decade of research in the basic and applied aspects of the use of serological means to diagnose and possibly treat breast cancer several milestones have been reached. Among them a clear understanding of immunopathological use and limitations of monoclonal antibodies against breast epithelium, the complete development and clinical use of immunoassays for circulating breast epithelial antigens, the striking advances in the diagnostic use of monoclonal antibodies to estrogen and progesterone receptor proteins and the first communications on proposed immunotherapeutic use of different conjugates of anti-breast antibodies. New areas of investigation have developed in our field, some which are reaching a full blossom while others are still facing obstacles and at times a re-definition of their goals and objectives. These meetings have acted in a way as a clearing house and have permitted their attendees to derive predictions that have helped shape future research and fine-tune objectives. But above all, the re-evaluation of past research at these Workshops and the renewed excitement brought to them by new information has helped generate a momentum and enthusiasm that assures for the future large scientific gains.

Editors and Affiliations

  • John Muir Cancer and Aging Research Institute, Walnut Creek, USA

    Roberto L. Ceriani

Bibliographic Information

  • Book Title: Breast Cancer Immunodiagnosis and Immunotherapy

  • Editors: Roberto L. Ceriani

  • DOI: https://doi.org/10.1007/978-1-4757-1296-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1989

  • Softcover ISBN: 978-1-4757-1298-8Published: 16 December 2012

  • eBook ISBN: 978-1-4757-1296-4Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XI, 259

  • Number of Illustrations: 67 b/w illustrations

  • Topics: Immunology

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