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  • © 1984

Physiology and Pathophysiology of the Heart

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 34)

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Table of contents (40 chapters)

  1. Front Matter

    Pages i-xv
  2. Cardiac Muscle

    1. Front Matter

      Pages 1-1
    2. Ultrastructure of Mammalian Cardiac Muscle

      • Michael S. Forbes, Nicholas Sperelakis
      Pages 3-42
    3. Basic Pathologic Processes of the Heart

      • L. Maximilian Buja
      Pages 43-57
    4. Electrogenesis of Pacemaker Potential as Revealed by AV Nodal Experiments

      • H. Irisawa, A. Noma, S. Kokubun, Y. Kurachi
      Pages 97-107
    5. Excitation-Contraction Coupling

      • Terence F. Mcdonald
      Pages 187-198
    6. The Role of Na-Ca Exchange in Heart

      • Lorin J. Mullins
      Pages 199-214
    7. Uptake of Calcium by the Sarcoplasmic Reticulum and Its Regulation and Functional Consequences

      • Michihiko Tada, Munekazu Shigekawa, Yasuharu Nimura
      Pages 255-277
    8. Neural Control of the Heart

      • Matthew N. Levy, Paul J. Martin
      Pages 337-354
    9. Mechanisms of Adrenergic and Cholinergic Regulation of Myocardial Contractility

      • August M. Watanabe, Jon P. Lindemann
      Pages 377-404
    10. The Pharmacology of the Cardiac Glycosides

      • Theodore M. Brody, Tai Akera
      Pages 405-419

About this book

could go on for several pages. Thus the book edited This book emphasizes the fundamental, functional aspects of cardiology. Within the last thirty years, by Sperelakis IS a potent reminder of the almost for­ the rift between clinical and investigative cardiology gotten fact that cardiology has twO sites, inextrica­ has widened, because of the overwhelming devel­ bly related. opment of new clinical procedures, both diagnostic The book deals with subjects in which Dr. Sper­ and therapeutic. Almost forgotten is the fact that elakis has pioneered: ultrastructure of heart muscle, we owe most of the clinical advances to theoretical electrophysiology, cardiac contractility, and ion ex­ and experimental observations. I need not remind change. An extension of these subjects is the chapter the reader of the work of Carrel, who performed the dealing with fundamental topics of the coronary cir­ first experimental coronary bypass in 1902, or the culation. work of the brothers Curie in 1880, both physicists, This book is indeed a timely reminder of the im­ who discovered piezoelectricity, the keystone in ech­ portance of the fundamental aspects of cardiology. ogradiography; of the works of Langley, who intro­ Emphasis on clinical aspects of cardiology alone will duced the receptors concept; of Ahlquist in 1946, result in a sterile and unproductive future for a field who first differentiated between alpha and beta re­ that has made such stunning advances during the ceptors; of Fleckenstein, a physiologist who pi­ last thirty years to the benefit of millions of people.

Reviews

`It is a book worth reading and presents an outstanding overview about the present day knowledge in the field whih has been thankfully put together in this edited version by Sperelakis. This book deserves to be recommended for those who are interested in the biochemistry, biochemical physiology, pharmacology and pathophysiology of the heart.'
Heart and Circulation, 19:9 (1985)

Editors and Affiliations

  • Department of Physiology, University of Cincinnati Medical Center, Cincinnati, USA

    Nicholas Sperelakis

Bibliographic Information

  • Book Title: Physiology and Pathophysiology of the Heart

  • Editors: Nicholas Sperelakis

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4757-1171-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag US 1984

  • eBook ISBN: 978-1-4757-1171-4Published: 29 June 2013

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XV, 846

  • Topics: Cardiology, Human Physiology

Buy it now

Buying options

eBook USD 74.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access