Overview
- Editors:
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Aurelio Rapado
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Fundación Jiménez Díaz, Madrid, Spain
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R. W. E. Watts
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M.R.C. Clinical Research Centre, Harrow, England
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Chris H. M. M. Bruyn
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Department of Human Genetics, University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
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Table of contents (71 chapters)
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Front Matter
Pages i-xxii
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Purine Metabolism Pathways and Regulation
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De Novo Synthesis: Precursors and Regulation
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- R. B. Gordon, L. Thompson, L. A. Johnson, B. T. Emmerson
Pages 1-6
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- Donald J. Nelson, Stephen W. LaFon, Gertrude B. Elion, J. Joseph Marr, Randolph L. Berens
Pages 7-12
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- E. R. Tully, T. G. Sheehan
Pages 13-17
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- Esther Zoref-Shani, Oded Sperling
Pages 19-24
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- S. Nees, A. L. Gerbes, B. Willershausen-Zönnchen, E. Gerlach
Pages 25-30
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- Kari O. Raivio, Cheri Lazar, Henry Krumholz, Michael A. Becker
Pages 31-34
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- Maria M. Jeżewska, Z. W. Kamiński
Pages 35-40
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Nucleotide Metabolism
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- Catherine M. Andres, Thomas D. Palella, Irving H. Fox
Pages 41-43
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- H.-G. Zimmer, H. Ibel, G. Steinkopff, H. Koschine
Pages 45-50
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Salvage Pathways
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- Thomas A. Krenitsky, George W. Koszalka, Joel V. Tuttle, David L. Adamczyk, Gertrude B. Elion, J. Joseph Marr
Pages 51-56
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- Roy A. Levine, Milton W. Taylor
Pages 57-60
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Catabolism
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- M. P. Rivera, M. R. Grau, J. Rigau, A. Goday
Pages 61-67
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- Costantino Salerno, Alessandro Giacomello
Pages 69-72
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- M. Kraupp, P. Chiba, M. M. Müller
Pages 73-78
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- Milton W. Taylor, Kailash C. Gupta, Ludmila Zawistowich
Pages 79-84
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- Georges Van den Berghe, Françoise Bontemps, Henri-Géry Hers
Pages 85-86
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Enzymology and Purine Metabolism
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Phosphoribosyltransferases
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- L. A. Johnson, R. B. Gordon, B. T. Emmerson
Pages 87-91
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- Alessandro Giacomello, Costantino Salerno
Pages 93-101
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- Milton W. Taylor, Howard V. Hershey
Pages 103-109
About this book
These volumes contain the papers which were presented at the Third International Symposium on Purine Metabolism in Man held in Madrid (Spain) in June, 1979. The previous meetings in the series were held in Tel Aviv (Israel) and in Baden (Austria) in 1973 and 1976, respectively. The proceedings were also published by Plenum. Knowledge of the pathophysiology of the purines has developed greatly since the 1950's when it was mainly related to clinical gout, and it is now relevant to many fields of Medicine and Biology. These volumes include papers reporting new work on clinical gout and urolithiasis as well as on some of the subjects which have featured prominently in the previous volumes, including: regulatory aspects of the intermediary metabolism of purines and related com pounds, enzymology, methodology, and the results of mutations which affect purine metabolism. However, there have been many new develop ments during the last three years and the scope of the communications reflects not only increasing depth of knowledge, but also a widening of the field. This publication has clinical and fundamental impli cations for internal medicine, pediatrics, urology, biochemistry, immunology, genetics, and oncology.
Editors and Affiliations
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Fundación Jiménez Díaz, Madrid, Spain
Aurelio Rapado
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M.R.C. Clinical Research Centre, Harrow, England
R. W. E. Watts
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Department of Human Genetics, University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands
Chris H. M. M. Bruyn