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Chromosome Damage and Repair

  • Book
  • © 1981

Overview

Editors:
  1. Erling Seeberg

    1. Norwegian Defense Research Establishment, Kjeller, Norway

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    You can also search for this editor in PubMed   Google Scholar

  2. Kjell Kleppe

    1. University of Bergen, Bergen, Norway

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 40)

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Table of contents (73 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Spontaneous and Induced Damage to DNA and Chromatin

    1. Front Matter

      Pages 1-1
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    2. Damage to DNA Caused by Hydrolysis

      • Robert Shapiro
      Pages 3-18

    3. Methylation of Cellular DNA by the Carcinogen N-Methyl-N-Nitrosourea and Removal of Methylpurines — Comparisons of Escherichia coli, Mouse and Human Cells

      • Philip D. Lawley
      Pages 19-24

    4. On the Use of a Damage-Specific DNA Binding Protein to Probe Lesions in DNA

      • Ross S. Feldberg
      Pages 25-29

    5. DNA Chemically Modified by N-Acetoxy-N-2-Acetyl-Aminofluorene : Nature of the Adducts and Conformation of the Modified DNA

      • Marc Leng, Evelyne Sage, Pascale Rio
      Pages 31-34

    6. Heteroduplex DNA in Bacteriophage T1 after Ionizing Radiation

      • Heidi Martin-Bertram
      Pages 35-39

    7. Influence of Alkylating Agents on the Structure of the Bacterial Nucleoid

      • Ivar Lossius, Kjell Kleppe
      Pages 41-47

    8. Nucleosomal Structure of Chromatin : Distribution and Excision of DNA Damage

      • Peter Cerutti, Motohisa Kaneko, Peter Beard
      Pages 49-61

    9. Electron-Microscopic Visualization of the AAF Binding Sites to DNA in Core Particles and Trinucleosomes by Means of Specific Antibodies

      • Robert P. P. Fuchs, M. C. Lang, G. de Murcia, A. Mazen, M. P. Daune
      Pages 63-68

    10. Studies of Molecular Events in Isolated Nucleolar Chromatin in Response to Chemicals and Ionizing Radiation

      • Ole Frederik Nielsen, Bernhard Borkhardt, Mahmut Carin, Børge F. Jensen, Dieter Jentsch, Johan C. Leer et al.
      Pages 69-73

  3. Mechanisms of DNA Excision Repair

    1. Front Matter

      Pages 75-75
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    2. Base Excision Repair of DNA

      • Errol C. Friedberg
      Pages 77-84

    3. Incision of Pyrimidine Dimer Containing DNA by Small Molecular Weight Enzymes

      • R. Grafstrom, N. Shaper, L. Grossman, W. Haseltine
      Pages 85-90

    4. The Use of Direct Photoreversal of UV-Irradiated DNA for the Demonstration of Pyrimidine Dimer-DNA Glycosylase Activity

      • Eric H. Radany, Jack D. Love, Errol C. Friedberg
      Pages 91-95

    5. Enzymatic Studies of Base Excision Repair in Cultured Human Fibroblasts and in Escherichia coli

      • Stuart Linn, Bruce Demple, Dale W. Mosbaugh, Huber R. Warner, Walter A. Deutsch
      Pages 97-112

    6. Mechanism of Action of M. luteus Apurinic/Apyrimidinic Endonucleases

      • Jacques Laval, Josiane Pierre
      Pages 113-116

    7. Properties of Uracil-DNA Glycosylases from M. luteus, E. coli and Mammalian Cells

      • Jacques Laval, Jean-Pierre Leblanc, Bernard Martin
      Pages 117-121

    8. Base Replacement Mechanisms for the Repair of Unnatural and Damaged Bases in DNA

      • Zvi Livneh, Joseph Sperling
      Pages 123-129

    9. Excision Repair of Bulky Lesions in the DNA of Mammalian Cells

      • R. B. Setlow, Eleanor Grist
      Pages 131-138
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Keywords

About this book

The NATO - EMBO Advanced Study Institute - Lecture Course on "CHROMOSOME DAMAGE AND REPAIR" was held at God¢ysund Fjord Hotel outside Bergen, Norway. from Ms\r 27th to June 5th, 1980. This book represents the proceedings of this meeting. In addition to the for­ mal lectures, a number of short contributions presented in the dis­ cussion sessions following the lectures are also included. The papers have been divided into different groups according to topic, essentially in the same way as they were presented during the meet­ ing. The editors have m. ade' few alterations in the manuscript sub­ mitted and these were mostly confined to typing style and correc­ tion ot typographical errors. We would like to express our appreciation to all the persons who helped in making this meeting possible. Special thanks are due to Tomas Lindahl, Alan R. Lehmann and Erik Boye, who served in the advisory program committee. We would also like to thank our Danish friends and colleagues and others who provided invaluable assistance in an emergency situation. The editors are also grateful for the financial support provided by a number of organizations and institu­ tions. First and foremost of these were the NATO Scientific Affairs Division and the European Molecular Biology Organization.

Editors and Affiliations

  • Norwegian Defense Research Establishment, Kjeller, Norway

    Erling Seeberg

  • University of Bergen, Bergen, Norway

    Kjell Kleppe

Bibliographic Information

  • Book Title: Chromosome Damage and Repair

  • Editors: Erling Seeberg, Kjell Kleppe

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4684-7956-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1981

  • Softcover ISBN: 978-1-4684-7958-4Published: 12 June 2012

  • eBook ISBN: 978-1-4684-7956-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 623

  • Topics: Animal Anatomy / Morphology / Histology

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