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Pharmacological Intervention in the Aging Process

  • Book
  • © 1978

Overview

Editors:
  1. Jay Roberts

    1. Medical College of Pennsylvania and Philadelphia Geriatric Center, USA

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  2. Richard C. Adelman

    1. Temple University Institute on Aging and Fels Research Institute and Philadelphia Geriatric Center, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Vincent J. Cristofalo

    1. The Wistar Institute and Philadelphia Geriatric Center, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 97)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xii
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  2. Drugs and the Older Person — A Brief Pharmacological Overview

    • H. George Mandel
    Pages 1-4

  3. Biotransformation of Drugs

    • James R. Gillette, Jack A. Hinson
    Pages 5-25

  4. Drug-Receptor Interactions

    • Lewis Aronow
    Pages 27-46

  5. Pharmacokinetic Assessment of the Effect of Age on the Disposition and Pharmacologic Activity of Drugs

    • Gerhard Levy
    Pages 47-53

  6. Genetic Control of Drug Metabolism

    • Daniel W. Nebert
    Pages 55-83

  7. Nutrition and Aging

    • Vernon R. Young
    Pages 85-110

  8. Protection Against Free Radical Lipid Peroxidation Reactions

    • Al. L. Tappel
    Pages 111-131

  9. Carcinogenesis and Aging

    • P. N. Magee
    Pages 133-146

  10. Perspectives on the Aged Myocardium

    • Edward G. Lakatta
    Pages 147-169

  11. Neuropharmacology and Aging

    • A. Horita
    Pages 171-185

  12. Chemical Manipulation of Some Aspects of Aging

    • James A. Clemens, Ray W. Fuller
    Pages 187-206

  13. Sex Hormones and Aging

    • Bernard A. Eskin
    Pages 207-224

  14. Summary and Remarks

    • Edward J. Cafruny
    Pages 225-230

  15. Pharmacological Interventions of the Aging Process

    • Robert N. Butler
    Pages 231-241

  16. Reinstatement of Ovarian Cycles in Aged Female Rats by Placement of L-Dopa in the Medial Preoptic Area

    • Ralph L. Cooper, Steven Brandt, Markku Linnoila, Louise H. Greenberg, Robert K. Dix, Benjamin Weiss et al.
    Pages 243-320

  17. Erratum to: Drug-Receptor Interactions

    • Lewis Aronow
    Pages 336-336

  18. Back Matter

    Pages 321-335
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Keywords

About this book

In the nearly three years that have elapsed since our first Philadelphia Symposium on Aging, our activities and interactions have expanded. We spent no small amount of time discussing the selection of a timely topic for our next symposium. For the first symposium, a variety of topics relating to the study of aging, ranging from phenomena at the cellular level to phenomena in disease states, were selected for consideration. For the present symposium, we thought it more desirable to concentrate on one area only, in order to summarize available information, discover what shortcomings exist, and suggest new directions for research. The paucity of in­ formation on pharmacological studies in aging and the compelling necessity for these studies made it clear to us that the time was appropriate for a review of this subject matter. The approach was to consider topics related to the effects of aging on the basic properties of drug action and on the effectiveness of drugs used in the therapy of diseases in several organ systems. Furthermore, it was felt that by considering the various pharmacological methods of intervention in the aging process, greater insight into the nature of aging would emerge. For the symposium, we brought together 13 outstanding workers in the field of pharmacology to discuss the selected topics. We expect that the chapters will be informative to workers in pharmacology and in biomedical disciplines in general, as well as provide a firm foundation for future work in this exciting area.

Editors and Affiliations

  • Medical College of Pennsylvania and Philadelphia Geriatric Center, USA

    Jay Roberts

  • Temple University Institute on Aging and Fels Research Institute and Philadelphia Geriatric Center, USA

    Richard C. Adelman

  • The Wistar Institute and Philadelphia Geriatric Center, USA

    Vincent J. Cristofalo

Bibliographic Information

  • Book Title: Pharmacological Intervention in the Aging Process

  • Editors: Jay Roberts, Richard C. Adelman, Vincent J. Cristofalo

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7793-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1978

  • Softcover ISBN: 978-1-4684-7795-5Published: 23 May 2013

  • eBook ISBN: 978-1-4684-7793-1Published: 29 June 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 357

  • Number of Illustrations: 28 b/w illustrations

  • Topics: Pharmacology/Toxicology

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