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The Thrombotic Process in Atherogenesis

  • Book
  • © 1978

Overview

Editors:
  1. A. Bleakley Chandler

    1. Department of Pathology, Medical College of Georgia, USA

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  2. Karl Eurenius

    1. National Heart, Lung, and Blood Institute, National Institutes of Health, USA

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  3. Gardner C. McMillan

    1. National Heart, Lung, and Blood Institute, National Institutes of Health, USA

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  4. Curtis B. Nelson

    1. Division of Scientific Affairs, American Heart Association, USA

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  5. Colin J. Schwartz

    1. Department of Pathology, University of Texas, San Antonio, USA

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  6. Stanford Wessler

    1. Department of Medicine, New York University School of Medicine, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 104)

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Table of contents (34 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Conceptual Aspects

    1. Front Matter

      Pages 1-1
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    2. Atherogenesis: The Process from Normal to Lesion

      • G. C. McMillan
      Pages 3-10

    3. The Geographic Pathology and Topography of Atherosclerosis and Risk Factors for Atherosclerotic Lesions

      • Jack P. Strong, Douglas A. Eggen, Richard E. Tracy
      Pages 11-31

    4. Light and Electron Microscopy of Human Atherosclerotic Lesions

      • M. Daria Haust
      Pages 33-59

    5. The Plasma Lipoproteins: Current Concepts of Metabolism and Structure with Clinical Implications

      • Antonio M. Gotto Jr.
      Pages 61-76

    6. Progression and Regression of Atherosclerotic Lesions

      • Robert W. Wissler
      Pages 77-109

    7. Clinical and Pathological Aspects of Arterial Thrombosis and Thromboembolism

      • Colin J. Schwartz, A. Bleakley Chandler, Ross G. Gerrity, Herbert K. Naito
      Pages 111-126

    8. Platelets, Thrombosis and Atherosclerosis

      • J. F. Mustard, M. A. Packham, R. Kinlough-Rathbone
      Pages 127-144

    9. Thrombosis and Atherosclerosis

      • Neville Woolf
      Pages 145-167

    10. Endothelium 1977: A Review

      • Guido Majno, Isabelle Joris
      Pages 169-225

    11. Atherosclerosis and Inflammation

      • Isabelle Joris, Guido Majno
      Pages 227-233

  3. Back Matter

    Pages 235-243
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  4. Interaction of Platelets and Coagulation with the Arterial Wall

    1. Front Matter

      Pages 245-245
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    2. Summary of Workshop a: Endothelium

      • R. L. Nachman, E. A. Jaffe, B. B. Weksler, F. A. Pitlick, M. A. Gimbrone Jr., C. R. Minick
      Pages 247-252

    3. Discussion Following Workshop 1a: Endothelium

      • A. Bleakley Chandler, Karl Eurenius, Gardner C. Mcmillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 253-256

    4. Summary of Workshop 1b: Smooth Muscle

      • W. A. Thomas, J. F. Mustard, S. Moore, M. J. Karnovsky, T. P. Bersot, H. Wolinsky
      Pages 257-265

    5. Discussion Following Workshop 1b: Smooth Muscle

      • A. Bleakley Chandler, Karl Eurenius, Gardner C. McMillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 267-269

  5. Risk Factors for Atherosclerosis and Thrombosis

    1. Front Matter

      Pages 271-271
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    2. Risk Factors for Atherosclerosis

      • Henry C. McGill Jr.
      Pages 273-280
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Keywords

About this book

Two infonnal meetings of consultants expert in hemostatic phenomena and in atherogenesis were held in Bethesda, Maryland, in December 1975 and February 1976 by the National Heart, Lung, and Blood Institute. Their purpose was to discuss the current status of knowledge concerning the thrombotic process in the pathogenesis of atherosclerosis. It was readily agreed that thrombosis often played a major role in plaque building and in plaque complication. It was also commented, however, that the data were qualitative in nature and that quantitative infonnation was remarkably sparse. The term thromboatherogenesis was thought to be appropriate for those phenomena in which the full expression of the thrombotic process is manifest. At the same time, recent research was noted in which what appears to be an important pathway for the initiation of atherogenesis arises from the reaction of platelets with injured arterial endothelium and'Subendothelium without necessarily involving the complete classical thrombotic process. A name was not coined for this circumstance, but it was held that thromboatherogenesis was not a fully appropriate one.

Editors and Affiliations

  • Department of Pathology, Medical College of Georgia, USA

    A. Bleakley Chandler

  • National Heart, Lung, and Blood Institute, National Institutes of Health, USA

    Karl Eurenius, Gardner C. McMillan

  • Division of Scientific Affairs, American Heart Association, USA

    Curtis B. Nelson

  • Department of Pathology, University of Texas, San Antonio, USA

    Colin J. Schwartz

  • Department of Medicine, New York University School of Medicine, USA

    Stanford Wessler

Bibliographic Information

  • Book Title: The Thrombotic Process in Atherogenesis

  • Editors: A. Bleakley Chandler, Karl Eurenius, Gardner C. McMillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7787-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1978

  • Softcover ISBN: 978-1-4684-7789-4Published: 26 November 2012

  • eBook ISBN: 978-1-4684-7787-0Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVI, 546

  • Number of Illustrations: 148 b/w illustrations

  • Topics: Cardiology, Hematology, Internal Medicine

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