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  • Book
  • © 1987

Molecular Mechanisms of Neuronal Responsiveness

Editors:

  1. Yigal H. Ehrlich

    1. The University of Vermont College of Medicine, Burlington, USA

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  2. Robert H. Lenox

    1. The University of Vermont College of Medicine, Burlington, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Elizabeth Kornecki

    1. The University of Vermont College of Medicine, Burlington, USA

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  4. William O. Berry

    1. Bolling A.F. Base, U.S. Air Force Office of Scientific Research, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 221)

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Table of contents (39 chapters)

  1. Front Matter

    Pages i-x
    PDF

  2. Signal Transduction and Stimulus-Response Coupling

    1. Further Studies on Depolarization Release Coupling in Squid Giant Synapse

      • R. Llinás, M. Sugimori, K. Walton
      Pages 1-17

    2. Temporal and Spatial Events in the Calcium Messenger System

      • Howard Rasmussen, Paula Barrett
      Pages 19-31

    3. Potassium Channels in Mouse Spinal Cord Cells

      • J. E. Kimura, B. McIver
      Pages 33-43

    5. Receptor-Mediated Phosphoinositide Metabolism

      • Bernard W. Agranoff
      Pages 69-79

    9. A Model of the Light Dependent Regulation of Retinal Rod Phosphodiesterase, Guanylate Cyclase and the Cation Flux

      • M. W. Bitensky, D. Torney, A. Yamazaki, M. M. Whalen, J. S. George
      Pages 107-121

    10. Regulation of Neuronal Adenylate Cyclase

      • M. M. Rasenick, M. M. Marcus, Y. Hatta, F. DeLeon-Jones, S. Hatta
      Pages 123-133

    11. Synapsin I, A Phosphoprotein Associated with Synaptic Vesicles: Possible Role in Regulation of Neurotransmitter Release

      • Paul Greengard, Michael D. Browning, Teresa L. McGuinness, Rodolfo Llinas
      Pages 135-153

    15. Expression of Rat Brain Excitatory Amino Acid Receptors in Xenopus Oocytes

      • Richard A. Lampe, Leonard G. Davis, Michael J. Gutnick
      Pages 201-210

    18. Molecular Mechanisms of Acidic Amino Acid Release from Mossy Fiber Terminals of Rat Cerebellum

      • David M. Terrian, Scott B. Bischoff, Monica A. Schwartz, Robert V. Dorman
      Pages 237-251

  3. Neuronal Adaptation and Synaptic Plasticity

    1. Molecular Mechanisms of β-Adrenergic Receptor Desensitization

      • David R. Sibley, Jeffrey L. Benovic, Marc G. Caron, Robert J. Lefkowitz
      Pages 253-273
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About this book

The interaction of neurotransmitters, neuromodulators and neuroactive drugs with receptors localized at the cell surface initiates a chain of molecular events leading to integrated neuronal responses to the triggering stimuli. Major advancements in the characterization and isolation of recep­ tor molecules have answered many quest ions regarding the nature of the ele­ ments that determine the specificity in these interactions. At the same time, recent studies have provided evidence that delicate regulation by intracellular enzymatic systems determines the efficiency of the stimulus­ response coupling process, mediates the interaction between receptors, operates in feedback control mechanisms and transduces signals from the receptors to various effector sites in a highly coordinated fashion. These studies are at the focus of the present volume, which is an outcome of a symposium held at the University of Vermont College of Medicine on March 21-23, 1986, in conjunction with the seventeenth annual meeting of the Amer­ ican Society for Neurochemistry. The symposium has demonstrated clearly that the concerted efforts of investigators in neurophysiology, biochemis­ try, pharmacology, cell-biology, molecular genetics, neurology, and psy­ chiatry are required to achieve better understanding of the processes under­ lying neuronal responsiveness. This volume includes contributions provided by prominent investigators in all these research areas. We hope that the readers will find here a useful source of information and ideas for stimu­ lating further studies which may serve to narrow the gap between basic neuroscience research and its clinical implications.
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Keywords

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Editors and Affiliations

  • The University of Vermont College of Medicine, Burlington, USA

    Yigal H. Ehrlich, Robert H. Lenox, Elizabeth Kornecki

  • Bolling A.F. Base, U.S. Air Force Office of Scientific Research, USA

    William O. Berry

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Bibliographic Information

  • Book Title: Molecular Mechanisms of Neuronal Responsiveness

  • Editors: Yigal H. Ehrlich, Robert H. Lenox, Elizabeth Kornecki, William O. Berry

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7618-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1987

  • Softcover ISBN: 978-1-4684-7620-0Published: 18 May 2012

  • eBook ISBN: 978-1-4684-7618-7Published: 13 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 563

  • Number of Illustrations: 107 b/w illustrations

  • Topics: Organic Chemistry

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Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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