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Pharmacological Control of Lipid Metabolism

Proceedings of the Fourth International Symposium on Drugs Affecting Lipid Metabolism held in Philadelphia, Pennsylvania, September 8–11, 1971

  • Conference proceedings
  • © 1972

Overview

Editors:
  1. William L. Holmes

    1. Division of Research, Lankenau Hospital, Philadelphia, USA

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  2. Rodolfo Paoletti

    1. Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

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  3. David Kritchevsky

    1. The Wistar Institute of Anatomy and Biology, Philadelphia, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 26)

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Table of contents (24 papers)

  1. Front Matter

    Pages i-xiii
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  2. Opening Remarks

    1. Opening Remarks

      • W. L. Holmes
      Pages 1-3

  3. Newer Developments in Lipid Biochemistry

    1. Front Matter

      Pages 5-5
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    2. Synthesis and Secretion of Plasma Lipoproteins

      • Robert L. Hamilton
      Pages 7-24

    3. The Apolipoproteins

      • Donald S. Fredrickson, Samuel E. Lux, Peter N. Herbert
      Pages 25-56

    4. Mechanisms of Hyperlipoproteinemia

      • Richard J. Havel
      Pages 57-70

    5. Clearing Factor Lipase and Its Role in the Regulation of Triglyceride Utilization. Studies on the Enzyme in Adipose Tissue

      • D. S. Robinson, D. R. Wing
      Pages 71-76

    6. Hormonal Control of Lipolysis in Adipose Tissue

      • Daniel Steinberg
      Pages 77-88

    7. The Role of Cyclic 3′5′-AMP and Its Derivatives in Lipid and Carbohydrate Metabolism

      • R. Paoletti
      Pages 89-89

    8. Biochemical Changes in the Artery Wall during Genesis and Regression of Atheromatous Lesions

      • H. B. Lofland Jr., R. W. St. Clair, T. B. Clarkson
      Pages 91-99

  4. Newer Aspects of Drugs Affecting Lipid Metabolism

    1. Front Matter

      Pages 101-101
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    2. Effect of Some Drugs on free Fatty Acids and Triglycerides in Plasma and Tissues

      • S. Garattini, M. E. Hess, M. T. Tacconi, E. Veneroni, A. Bizzi
      Pages 103-112

    3. Effect of Drugs on Plasma Triglyceride Metabolism

      • Esko A. Nikkilä
      Pages 113-133

    4. The Economy of Cholesterol in Man: Drug Effects

      • E. H. Ahrens Jr.
      Pages 135-135

    5. Effects of Drugs on the Metabolism of Bile Acids

      • N. B. Myant
      Pages 137-154

    6. Hypolipidemic Drugs and Lipoprotein Metabolism

      • Robert I. Levy, Terry Langer
      Pages 155-163

    7. Serum and Tissue Lipid Metabolism and Effect of Nicotinic Acid in Different Types of Hyperlipidemia

      • Lars A. Carlson, Göran Walldius
      Pages 165-178

    8. The Combined Use of Clofibrate and Anion Exchange in the Treatment of Hypercholesterolemia

      • A. N. Howard, D. E. Hyams, R. Courtenay Evans
      Pages 179-187

  5. Can Heart Disease be Postponed or Prevented?

    1. Front Matter

      Pages 189-189
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    2. Atherogenic and Thrombogenic Mosaic

      • Irvine H. Page
      Pages 191-194
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Keywords

About this book

This Symposium was the fourth in a series which began in Milan, Italy, in 1960. Each meeting has introduced or developed some new concepts in the areas of lipid metabolism and drugs. The meetings have served as a springboard for new ideas which have, between meetings, become accepted and exploited. This meeting has been no exception. Principal among the many new concepts discussed were lipoprotein synthesis and metabolism, apoprotein structure and function, whole body metabolism of cholesterol, and aspects of myocardial and aortic metabolism. The Symposium also included a summary of current thought on management of hyperlipemias and atherosclerosis. Data on more than 30 drugs were introduced and discussed. We have every expectation that the next Symposium will include material which is now only in the formative stage. The Organizing Committee would like to acknowledge the invaluable assistance of Miss Mary Constant, Mr. Ralph H. Hollerorth, Mrs. Carolyn P. Hyatt and Miss Jane T. Kolimaga, whose efforts contributed significantly (p < .001) to the success of this Symposium.

Editors and Affiliations

  • Division of Research, Lankenau Hospital, Philadelphia, USA

    William L. Holmes

  • Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

    Rodolfo Paoletti

  • The Wistar Institute of Anatomy and Biology, Philadelphia, USA

    David Kritchevsky

Bibliographic Information

  • Book Title: Pharmacological Control of Lipid Metabolism

  • Book Subtitle: Proceedings of the Fourth International Symposium on Drugs Affecting Lipid Metabolism held in Philadelphia, Pennsylvania, September 8–11, 1971

  • Editors: William L. Holmes, Rodolfo Paoletti, David Kritchevsky

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7547-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1972

  • Softcover ISBN: 978-1-4684-7549-4Published: 02 March 2013

  • eBook ISBN: 978-1-4684-7547-0Published: 29 June 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIII, 359

  • Number of Illustrations: 49 b/w illustrations

  • Topics: Pharmacology/Toxicology

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