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Biochemical Pharmacology of Ethanol

  • Book
  • © 1975

Overview

Editors:
  1. Edward Majchrowicz

    1. Laboratory of Alcohol Research, National Institute on Alcohol Abuse and Alcoholism, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 56)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xv
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  2. Mammalian Liver Alcohol Dehydrogenases

    • Regina Pietruszko
    Pages 1-31

  3. Microsomal Ethanol Oxidation: Activity in Vitro and in Vivo

    • Mary K. Roach
    Pages 33-55

  4. Pathways of Ethanol Metabolism in Perfused Rat Liver

    • Ronald G. Thurman, William R. McKenna
    Pages 57-76

  5. Rate-Limiting Steps in Ethanol Metabolism and Approaches to Changing These Rates Biochemically

    • Bryce V. Plapp
    Pages 77-109

  6. Metabolic Correlates of Ethanol, Acetaldehyde, Acetate and Methanol in Humans and Animals

    • Edward Majchrowicz
    Pages 111-140

  7. Alcohol and Aldehyde Metabolism in Brain

    • Boris Tabakoff, Catherine C. Gelpke
    Pages 141-164

  8. Effects of Ethanol on Brain Metabolism

    • Arun K. Rawat
    Pages 165-177

  9. Effects of Ethanol on Protein Synthesis

    • Marcus A. Rothschild, Sidney S. Schreiber, Murray Oratz
    Pages 179-194

  10. The Effects of Aliphatic Alcohols on the Biophysical and Biochemical Correlates of Membrane Function

    • Walter A. Hunt
    Pages 195-210

  11. Interactions of Ethanol with Cyclic AMP

    • Ladislav Volicer, Barry I. Gold
    Pages 211-237

  12. Alcohol, Aldehydes and Biogenic Amines

    • Robert A. Lahti
    Pages 239-253

  13. Formation of Aberrant Neurotransmitters and Its Implication for Alcohol Addiction and Intoxication

    • Spyridon G. A. Alivisatos, Ramesh C. Arora
    Pages 255-263

  14. Interaction of Biogenic Amines with Ethanol

    • Alfred A. Smith
    Pages 265-275

  15. Some Endocrine Aspects of Alcoholism

    • Robert W. Farmer, Louis F. Fabre Jr.
    Pages 277-289

  16. Marihuana vs. Alcohol: A Pharmacologic Comparison

    • Edward B. Truitt Jr.
    Pages 291-309

  17. Induction of Physical Dependence on Alcohol in Rodents

    • Gerhard Freund
    Pages 311-325

  18. Induction of Physical Dependence upon Alcohol in Nonhuman Primates

    • Walter A. Pieper
    Pages 327-337

  19. Genetic Determinants of Alcohol Addiction

    • Donald W. Goodwin
    Pages 339-355

  20. Back Matter

    Pages 357-367
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Keywords

About this book

A number of excellent symposia, reviews and monographs on the biology of ethanol have been published during the last decade. Al­ though it may appear that another such publication may be superflu­ ous, the subject of alcohol abuse is still open for further explora­ tion and the field of the biochemical pharmacology of ethanol is in its infancy. This is evidenced, for example, by the unavailability of any drugs that are designed specifically for the treatment of alcohol intoxication or alcohol addiction. The impetus for this publication was generated by a spontane­ ous enthusiasm following the symposium on BiochemicaZ Ph~acoZogy of EthanoZ that was organized at the annual meeting of the American Chemical Society, Division of Biological Chemistry in August 1973 in Chicago. It was the first symposium on such a topic ever in­ cluded in the program of that large society of American chemists. The original aim of the symposium was to acquaint the members of the society with some basic facts about the biological chemistry of ethanol. The symposium included seven papers and covered a rela­ tively narrow range of ethanol biochemistry. In view of the enthu­ siasm shown at the Chemical Society meeting, the panelists decided to publish the program and to amplify it by inclusion of additional topics which have remained relatively unexplored in earlier publica­ tions. In addition, reviews have been included which discuss old topics from a new perspective.

Editors and Affiliations

  • Laboratory of Alcohol Research, National Institute on Alcohol Abuse and Alcoholism, USA

    Edward Majchrowicz

Bibliographic Information

  • Book Title: Biochemical Pharmacology of Ethanol

  • Editors: Edward Majchrowicz

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7529-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1975

  • Softcover ISBN: 978-1-4684-7531-9Published: 19 April 2012

  • eBook ISBN: 978-1-4684-7529-6Published: 11 November 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XV, 367

  • Topics: Pharmacology/Toxicology

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