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Gastrointestinal Hormones and Pathology of the Digestive System

  • Book
  • © 1978

Overview

Editors:
  1. Morton Grossman

    1. Veterans Administration, Wadsworth Hospital Center, Los Angeles, USA

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  2. V. Speranza

    1. Institute of 3rd Surgical Pathology, University of Rome, Italy

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  3. N. Basso

    1. Institute of 3rd Surgical Pathology, University of Rome, Italy

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  4. E. Lezoche

    1. Institute of 3rd Surgical Pathology, University of Rome, Italy

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 106)

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Table of contents (40 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. The Gastrointestinal Hormones: An Overview

    • R. A. Gregory
    Pages 1-4

  3. A Short History of Digestive Endocrinology

    • M. I. Grossman
    Pages 5-10

  4. Endocrine Cells of the Gastrointestinal Tract: General Aspects, Ultrastructure and Tumour Pathology

    • E. Solcia, C. Capella, R. Buffa, L. Usellini, P. Fontana, B. Frigerio
    Pages 11-22

  5. How does a Candidate Peptide Become a Hormone?

    • M. I. Grossman
    Pages 23-25

  6. Peptidergic Innervation of the Gastrointestinal Tract

    • J. M. Polak, S. R. Bloom
    Pages 27-49

  7. Polypeptides of the Amphibian Skin Active on the Gut and Their Mammalian Counterparts

    • V. Erspamer, P. Melchiorri, C. Falconieri Erspamer, L. Negri
    Pages 51-64

  8. Paired Immunohistochemical Staining of Gastrin-Producing Cells (G Cells) and Parietal Cells in Paraffin Sections of Human Gastric Mucosa

    • R. Stave, P. Brandtzaeg, J. Myren, K. Nygaard, E. Gjone
    Pages 65-68

  9. Histamine H2-Receptors and Gastric Secretion

    • G. Bertaccini
    Pages 69-74

  10. The Gastrins: Structure and Heterogeneity

    • R. A. Gregory
    Pages 75-83

  11. Biological Activity and Clearance of Gastrin Peptides in Dog and Man: Effects of Varying Chain Length of Peptide Fragments

    • J. H. Walsh
    Pages 85-89

  12. Different Forms of Gastrin in Peptic Ulcer

    • G. J. Dockray, I. L. Taylor
    Pages 91-96

  13. Antral G Cells and Mucosal Gastrin Concentration in Normal Subjects and in Patients with Duodenal Ulcer

    • L. Barbara, G. Biasco, M. Salera, F. Baldi, G. Di Febo, M. Miglioli
    Pages 97-104

  14. Role of the Small Bowel in Regulating Serum Gastrin and Gastric Inhibitory Polypeptide (GIP) Levels and Gastric Acid Secretion

    • H. D. Becker, N. J. Smith, H. W. Börger, A. Schafmayer
    Pages 105-110

  15. Cimetidine Treatment in Zollinger-Ellison Syndrome

    • S. Bonfils, M. Mignon, G. Kloeti
    Pages 111-116

  16. Calcitonin, Parathyroid Hormone and Insulin Concentrations in Sera from Patients with Gastrinoma

    • M. Cecchettin, A. Albertini, G. Bonora, P. Vezzadini
    Pages 117-119

  17. Hormonal Control of the Lower Esophageal Sphincter in Man and Dog: Reevaluation of the Present Manometric Method for Diagnosis of GE Reflux

    • Z. Itoh, R. Honda, K. Hiwatashi, I. Takahashi
    Pages 121-131

  18. Progress in Intestinal Hormone Research

    • V. Mutt
    Pages 133-146

  19. Trophic Effects of Endogenous and Exogenous Pancreozymin Upon the Exocrine and Endocrine Pancreas

    • T. Fujita, Y. Matsunari, Y. Koga, K. Sato, M. Hayashi
    Pages 147-150

  20. Enteropancreatic Axis

    • S. R. Bloom, J. M. Polak
    Pages 151-163
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Keywords

About this book

The discovery that the same or similar peptides are present in endocrine cells and in neurons is one of the most exciting and provocative recent developments in biology. Suddenly neurophysiologists and endocrinologists have found that they have a great deal to discuss with each other. Substances originally isolated as hypothalamic hormones turn out to be abundantly present in neurons of other parts of the brain and in endocrine cells and neurons of the gut and pancreas. Similarly, substances originally isolated as gut hormones are found not only in gut endocrine cells but also in gut neurons and in brain neurons. It turns out that the group of peptides that we are accustomed to call gastrointestinal hormones are not all confined to the gastrointestinal tract and are not all solely hormones. We are learning that the chemical transmitters of the neurocrine, endocrine, and paracrine systems form a single group of related substances. This volume contains the latest installments in this fascinating story. It tells how these pep tides were isolated and their amino acid sequences determined, how the heterogeneity of most, perhaps all, of these peptides is being revealed as variant forms of them are discovered, how antibodies to these peptides are used as powerful tools to measure their concentrations in body fluids and to localize the cells in which they are synthesized and stored, and, finally, how the role of these substances in normal physiology and in pathological states is being unraveled.

Editors and Affiliations

  • Veterans Administration, Wadsworth Hospital Center, Los Angeles, USA

    Morton Grossman

  • Institute of 3rd Surgical Pathology, University of Rome, Italy

    V. Speranza, N. Basso, E. Lezoche

Bibliographic Information

  • Book Title: Gastrointestinal Hormones and Pathology of the Digestive System

  • Editors: Morton Grossman, V. Speranza, N. Basso, E. Lezoche

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-7248-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1978

  • Softcover ISBN: 978-1-4684-7250-9Published: 31 July 2013

  • eBook ISBN: 978-1-4684-7248-6Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 326

  • Number of Illustrations: 32 b/w illustrations

  • Topics: Gastroenterology

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