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The Molecular Basis of B-Cell Differentiation and Function

  • Book
  • © 1986

Overview

Editors:
  1. M. Ferrarini

    1. Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy

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  2. B. Pernis

    1. College of Physicians and Surgeons, Columbia University, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 123)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-viii
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  2. Regulation of the Assembly and Expression of Immunoglobulin Genes: Variable Region Assembly and Heavy Chain Class Switching

    • R. A. DePinho, G. D. Yancopoulos, T. K. Blackwell, M. G. Reth, K. Kruger, S. G. Lutzker et al.
    Pages 1-17

  3. Acquired Alterations Around the Cε Gene in Cultured Mouse Myeloma Cells

    • Charles-Félix Calvo, Barbara K. Birshtein
    Pages 19-21

  4. Differentiation in the I.29 B Cell Lymphoma: Precommitment to IgA or IgE Switch in Individual IgM+ Clones

    • R. Sitia, C. Alberini, R. Biassoni, S. DeAmbrosis, D. Vismara
    Pages 23-28

  5. Transcriptional and Post-Transcriptional Control of Ig-Gene Expression in Murine B-Cells Activated by LPS and Anti-Receptor Antibodies

    • Una Chen-Bettecken, Eberhard Wecker, Anneliese Schimpl
    Pages 29-32

  6. Restricted Set of V Genes and Extensive Idiotype Crossreactivity of Autoantibodies

    • Marc Monestier, Catherine Painter, Audrey Manheimer-Lory, Blanche Bellon, Constantin Bona
    Pages 33-39

  7. Antigen-Specific Stimulation of Human Autoreactive B Lymphocytes

    • T. Logtenberg, A. Kroon, F. H. J. Gmelig-Meyling, R. E. Ballieux
    Pages 41-44

  8. Isotype Restriction of Idiotopes found on Human Anti-Carbohydrate Antibodies

    • F. Emmrich, G. Zenke, K. Eichmann
    Pages 45-47

  9. Control of the Mitotic B Cell Cycle: Facts and Speculations

    • Fritz Melchers
    Pages 49-57

  10. The Effects of Interleukin 2, Gamma Interferon, and B Cell Differentiation Factor on the Differentiation of Human B Cells

    • N. Nakagawa, T. Nakagawa, D. J. Volkman, H. Goldstein, J. L. Ambrus Jr., A. S. Fauci
    Pages 59-62

  11. Regulation of Human B Cell Proliferation and Differentiation by Interleukin 2

    • Diane F. Jelinek, Peter E. Lipsky
    Pages 63-66

  12. Application of the Staphylococcus Aureus Bacteria to the Study of Human B Cell Proliferation and Differentiation

    • Sergio Romagnani
    Pages 67-78

  13. A Model for the First Activation Cycle of Human B Lymphocytes

    • J. Gordon, G. Guy, L. Walker
    Pages 79-82

  14. Control of B Cell Activation by Helper T Cells

    • Kim Bottomly, John P. Tite, Barry Jones, Eileen Becker-Dunn, Jonathan Kaye, Abraham Kupfer et al.
    Pages 83-94

  15. Antigen Processing and Presentation by B Cells

    • Howard M. Grey, Robert Chesnut, Jeffrey Krieger
    Pages 95-107

  16. The Role of Receptor Immunoglogulin in Antigen-Specific, MHC-Restricted T Cell/B Cell Cooperation

    • David C. Parker, Hans-Peter Tony
    Pages 109-116

  17. Clonal Analysis of Human T Lymphocytes Inducing B Cell Growth

    • Maria Cristina Mingari, Lorenzo Moretta
    Pages 117-122

  18. Private and Shared Idiotypic Determinants of the Human T Cell Antigen Receptor

    • Robert D. Bigler, Nicholas Chiorazzi
    Pages 123-130

  19. Molecular Markers of Clonality, Lineage, Differentiation, and Translocation in B Cell Neoplasms

    • Stanley J. Korsmeyer, Ajay Bakhshi, John J. Wright, Winfried C. Graninger, Carolyn Felix, Masao Seto
    Pages 131-139

  20. Heavy Chain Diseases

    • Maxime Seligmann
    Pages 141-149
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Keywords

About this book

The progress in protein and nucleic acid chemistry together with improvements of the previously employed tissue culture techniques have led to the solution of problems such as that of the generation of antibody diversity or of the molecular structure of T and B cell membrane receptor for antigen which had challenged the past generations of immunologists. Thanks to this progress an impressive amount of knowledge has been accumulated on certain cell types that were relatively "mysterious" until recently. The B lymphocyte represents a typical example of such a cell. With these considerations in mind, we have started to organize a NATO summer school on "The molecular basis of B cell differentation and function" that had the specific aim of bringing up to date a selected number of young investigators. During the course, held in Santa Margheri ta Ligure, October 1-11, 1985 it became apparent that rather than a formal school we had organized an informal series of Workshops where both the Faculty members and the participants were discussing their own data in addition to reviewing the general progress in the field. The deep commi ttment of everyone to his research subj ect and the enthusiasm had caused this very successful change in the shape of the course. At the end we asked the members of the Faculty and the participants to write a summary of their data and of their point of view on selected subj ect s.

Editors and Affiliations

  • Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy

    M. Ferrarini

  • College of Physicians and Surgeons, Columbia University, New York, USA

    B. Pernis

Bibliographic Information

  • Book Title: The Molecular Basis of B-Cell Differentiation and Function

  • Editors: M. Ferrarini, B. Pernis

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4684-7035-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1986

  • Softcover ISBN: 978-1-4684-7037-6Published: 25 November 2012

  • eBook ISBN: 978-1-4684-7035-2Published: 09 March 2013

  • Edition Number: 1

  • Number of Pages: VIII, 173

  • Number of Illustrations: 13 b/w illustrations

  • Topics: Difference and Functional Equations

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