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  • Book
  • © 1991

Molecular Pathogenesis of Gastrointestinal Infections

Editors:

  1. T. Wadström

    1. University of Lund, Lund, Sweden

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  2. P. H. Mäkelä

    1. National Public Health Institute, Helsinki, Finland

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  3. A.-M. Svennerholm

    1. University of Gothenburg, Gothenburg, Sweden

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  4. H. Wolf-Watz

    1. University of Umeå, Umeå, Sweden

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Part of the book series: F.E.M.S. Symposium Series (FEMS, volume 58)

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Table of contents (48 chapters)

  1. Front Matter

    Pages i-x
    PDF

  2. The Mucosal Surface

    1. The Enterocyte and its Brush Border

      • Robert W. Lobley
      Pages 1-8

    2. Characteristics of the Recognition of Host Cell Carbohydrates by Viruses and Bacteria

      • Karl-Anders Karlsson, Jonas Ångström, Susann Teneberg
      Pages 9-21

    3. Structure and Properties of Rat Gastrointestinal Mucins

      • Ingemar Carlstedt, Stefan Elmquist, Ingela Ljusegren, Gunnar C. Hansson
      Pages 23-28

    4. The Role of Large Intestine Mucus in Colonization of the Mouse Large Intestine by Escherichia Coli F-18 and Salmonella Typhimurium

      • Paul S. Cohen, Beth A. McCormick, David P. Franklin, Robert L. Burghoff, David C. Laux
      Pages 29-31

    5. Germfree Animals Intestinal Glycoconjugates and Colonization

      • Tore Midtvedt, Göran Larson, Catharina Svanborg
      Pages 33-36

  3. The Parasite

    2. Genetics of Histone-Like Protein H-NS/H1 and Regulation of Virulence Determinants in Enterobacteria

      • Bernt Eric Uhlin, Björn Dagberg, Kristina Forsman, Mikael Göransson, Birgit Knepper, Peter Nilsson et al.
      Pages 55-58

    3. Regulation of Expression of Fimbriae of Human Enterotoxigenic Escherichia Coli

      • Wim Gaastra, Anja M. Hamers, Bart J. A. M. Jordi, Paul H. M. Savelkoul, Geraldine A. Willshaw, Moyra M. McConnell et al.
      Pages 61-70

    4. Function and Molecular Architecture of E.Coli Adhesins

      • Heinz Hoschützky, Thomas Bühler, Ralph Ahrens, Klaus Jann
      Pages 71-78

    6. Molecular Biology of Escherichia coli Type 1 Fimbriae

      • Per Klemm, Karen A. Krogfelt
      Pages 87-92

    8. Diffuse Adherence Of Enteropathogenic Escherichia coli Strains

      • Inga Benz, M. Alexander Schmidt
      Pages 103-105

  4. Enterotoxigenic Organisms

    2. Cholera Toxin: Assembly, Secretion and in Vivo Expression

      • J. Holmgren, S. J. S. Hardy, T. R. Hirst, S. Johansson, G. Jonson, J. Sanchez et al.
      Pages 115-124

    3. Heat-Stable Enterotoxins Produced by Enteric Bacteria

      • Yoshifumi Takeda, Shinji Yamasaki, Toshiya Hirayama, Yasutsugu Shimonishi
      Pages 125-138
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About this book

The meeting that provided the material for this book was the 58th Symposium of the Federation of European Microbiological Societies (FEMS) entitled MOLECULAR PATHOGENESIS OF GASTROINTESTINAL INFECTIONS which was held in Helsingor, Denmark from 2nd to 4th September, 1990. The aim of this meeting was to bring together scientists from a range of discipline- microbiology, cell biology, molecular biology and immunology - to consider how microbes, including parasites, colonize and infect the gastrointestinal tract. The programme was designed to focus particular attention on the range of strategies whereby enterovirulent bacteria and parasites colonize the gastrointestinal mucin layer, how they adhere to and penetrate the epithelial layer by entering the cells or passing between them, and how various protein toxins may facilitate these processes. Speakers were especially encouraged to highlight the recent expansion in our knowledge of the molecular mechanisms by which enterotoxigenic and enteropathogenic Escherichia coli, shigellae, salmonellae and Yersinia enterocolitica cause intestinal disease. There were also discussions of recently-discovered gastrointestinal pathogens such as Clostridium difficile and Helicobacter pylori as well as accounts of how virulent determinants can be used to develop new diagnostic methods based on DNA gene probes and the polymerase chain reaction (PCR). These presentations provided the basis for the chapters in this book.
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Keywords

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Editors and Affiliations

  • University of Lund, Lund, Sweden

    T. Wadström

  • National Public Health Institute, Helsinki, Finland

    P. H. Mäkelä

  • University of Gothenburg, Gothenburg, Sweden

    A.-M. Svennerholm

  • University of Umeå, Umeå, Sweden

    H. Wolf-Watz

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Bibliographic Information

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Access via your institution

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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