Skip to main content
SpringerLink
Log in

Genetics and Product Formation in Streptomyces

  • Book
  • © 1991

Overview

Editors:
  1. Simon Baumberg

    1. University of Leeds, Leeds, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Hans Krügel

    1. Institut für Mikrobiologie und Experimentelle Therapie, Jena, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Dieter Noack

    1. Institut für Mikrobiologie und Experimentelle Therapie, Jena, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: F.E.M.S. Symposium Series (FEMS, volume 55)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (38 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Transcription/Translation, Primary/Secondary Metabolism, Differentiation

    1. Introduction

      • K. F. Chater
      Pages 1-2

    2. Gene Expression during Sporulation in Streptomyces Coelicolor A3(2)

      • Keith F. Chater, Celia J. Bruton, Nigel K. Davis, Kitty A. Plaskitt, Juan Soliveri, Huarong Tan
      Pages 3-9

    3. Presence of Factor C in Streptomycetes and Other Bacteria

      • F. Szeszák, S. Vitális, I. Békési, G. Szabó
      Pages 11-18

    4. Steptomyces Griseus Proteins Post-Translationally Modified by ADP-Ribosylation During the Life Cycle

      • Andras Penyige, Gyorgy Barabas, Jerald C. Ensign
      Pages 19-27

    5. Induction of the Stringent Response in Streptomyces Coelicolor A3(2) and Its Possible Role in Antibiotic Production

      • E. Strauch, E. Takano, M. J. Bibb
      Pages 29-33

    6. The Relationship Between Primary and Secondary Metabolism in Streptomycetes

      • G. Padilla, Z. Hindle, R. Callis, A. Corner, M. Ludovice, P. Liras et al.
      Pages 35-45

    7. Isolation and Sequence of a tRNAGly (CCC) from Streptomyces coelicolor A3(2)

      • J. Stefan Rokem, Astrid Schön, Dieter Söll
      Pages 47-52

    8. Measurement of Translational Accuracy in Streptomyces

      • J. Weiser, J.-L. Pernodet, M. Cassan, M. Ehrenberg, J. Náprstek, M. Guerineau et al.
      Pages 53-63

    9. t-RNA Genes in Streptomyces Lividans: Structure, Organization and Construction of Suppressor t-RNA

      • Reinhard Sedlmeier, Horst Schmieger
      Pages 65-73

    10. Characterization of Eight Groups (Species) of Saccharopolyspora Phages — An Example for Studying Modular Organization of Actinophage Genomes

      • Jörg Schneider
      Pages 75-82

  3. Antibiotic Synthesis

    1. Antibiotic Biosynthesis

      • Iain S. Hunter
      Pages 83-85

    2. Cephamycin Production by Streptomyces Clavuligerus

      • A. L. Demain, J. M. Piret
      Pages 87-103

    3. Molecular Genetics of Oxytetracycline Production by Streptomyces rimosus

      • Kenneth J. McDowall, Deirdre Doyle, Michael J. Butler, Craig Binnie, Melvyn Warren, Iain S. Hunter
      Pages 105-116

    4. Genetic Characterization and Cloning of Genes for Chlortetracycline Resistance in Streptomyces Aureofaciens Strains

      • Natalie Lomovskaya, Gennady Sezonov, Lyubov Isayeva, Tatyana Chinenova
      Pages 117-127

    5. Bromoperoxidase from Streptomyces Aureofaciens Tü24 and its Role in 7-Chlorotetracycline Biosynthesis

      • Helmut Häcker, Otto Pfeifer, Frauke Thiermann, Maria Weng, Franz Lingens, Karl-Heinz van Pée
      Pages 129-136

    6. Enzymes and Coenzymes of the Terminal Part of the Antibiotic Biosynthetic Pathway in Streptomycetes Producing Tetracyclines

      • J. Novotná, J. Neužil, I. Vančurová, V. Běhal, Z. Hošt’álek
      Pages 137-143

    7. Molecular Genetic Investigation of Streptomyces Bambergiensis and Streptomyces Fradiae Strains, the Producers of Flavomycin and Tylosin

      • A. V. Orekhov, S. B. Zotchev, G. Y. Florova, A. R. Foors, L. B. Gul’ko, S. M. Rosenfeld et al.
      Pages 145-152

  4. Antibiotic Resistance

    1. Antibiotic Resistance: Present State and Prospects

      • Wolfgang Piepersberg
      Pages 153-159

    2. Evolution of Antibiotic Resistance and Production Genes in Streptomycetes

      • Wolfgang Piepersberg, Peter Heinzel, Kambiz Mansouri, Ulrike Mönnighoff, Klaus Pissowotzki
      Pages 161-170
Back to top

Keywords

About this book

The Streptomycetes are industrially widely used microorganisms due to their ability to produce numerous different chemical compounds. These show very varied effects upon other living systems, and result from profound and subtle biochemical and morphological differentiation during the streptomycete life cycle. It is therefore not surprising that research on the genetics of antibiotic biosynthesis and differentiation in this group is currently progressing rapidly in many countries. Intimately connected with the production of antibiotics is resistance to them; analysis of this is giving further information about the origin and evolution of this class of genes and their hypothesized spread among other microorganisms. Another interesting feature of the Streptomyces group is their mycelial growth. Also, their ecologically important utilization of high molecular weight compounds requires enzymes to be transported outside the cell to hydrolyze non-diffusible substrates. Finally, we have as yet limited understanding of the various mechanisms of genome rearrangement observed in some of these species; deletions and/or amplifications of enormous amounts of DNA can occur without seriously affecting the viability of the organism under laboratory conditions. The present volume, which includes contributions addressing the above subjects and others, originates from a meeting on "Genetics and Product Formation in Streptomyces" sponsored by the Federation of European Microbiological Societies in Erfurt on May 1-6 1990. Compared to previous ones of this kind held in 1979, 1983 and 1987 in Weimar, one can point to impressive progress in the study and applications of Streptomyces genetics.

Editors and Affiliations

  • University of Leeds, Leeds, UK

    Simon Baumberg

  • Institut für Mikrobiologie und Experimentelle Therapie, Jena, Germany

    Hans Krügel, Dieter Noack

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation