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Myoblast Transfer Therapy

  • Book
  • © 1990

Overview

Editors:
  1. Robert C. Griggs

    1. University of Rochester, Rochester, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. George Karpati

    1. McGill University, Montreal, Canada

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 280)

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Table of contents (35 chapters)

  1. Front Matter

    Pages i-xii
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  2. Molecular Biology of Myogenesis and Regeneration

    1. Front Matter

      Pages 1-1
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    2. MyoD: A Regulatory Gene of Skeletal Myogenesis

      • Stephen J. Tapscott, Robert L. Davis, Andrew B. Lassar, Harold Weintraub
      Pages 3-6

    3. Myoblasts, Satellite Cells, and Myoblast Transfer

      • Frank E. Stockdale, E. Janet Hager, Susan E. Fernyak, Joseph X. DiMario
      Pages 7-11

    4. Regeneration of Skeletal Muscle Fibers after Necrosis

      • Stirling Carpenter
      Pages 13-15

    5. Detection of Truncated Dystrophin in Fetal DMD Myotubes

      • Ieke B. Ginjaar, Egbert Bakker, Johan T. den Dunnen, Andy Wessels, Marleen M. B. van Paassen, Maarten D. Kloosterman et al.
      Pages 17-23

  4. Practical Aspects of Myoblast Implantation

    1. Front Matter

      Pages 67-67
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    2. The Principles and Practice of Myoblast Transfer

      • George Karpati
      Pages 69-74

    3. Myoblast Transfer Improves Muscle Genetics/Structure/Function and Normalizes the Behavior and Life-Span of Dystrophic Mice

      • Peter K. Law, Tena G. Goodwin, H.-J. Li, Ghaith Ajamoughli, Ming Chen
      Pages 75-87

    4. Practical Aspects of Myoblast Implantation: Investigations on Two Inherited Myopathies in Animals

      • Jennifer E. Morgan
      Pages 89-96

    5. Purification and Proliferation of Human Myoblasts Isolated with Fluorescence Activated Cell Sorting

      • Helen M. Blau, Cecelia Webster, Grace K. Pavlath
      Pages 97-100

    6. The Proliferation and Fusion of Myoblasts In Vivo

      • Miranda D. Grounds
      Pages 101-106

    7. The DMD Gene Promoter: A Potential Role in Gene Therapy

      • Peter N. Ray, Henry J. Klamut, Ronald G. Worton
      Pages 107-112

  5. In Situ Fusion: Nuclear Domains and mRNA/Protein Migration

    1. Front Matter

      Pages 129-129
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    2. Fibroblasts Fuse with Myotubes Developing in Culture

      • Nirupa Chaudhari, Kurt G. Beam
      Pages 131-137
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About this book

I am pleased to introduce this volume on Myoblast Transfer Therapy on behalf of the Muscular Dystrophy Association and all of its Advisory Committees. The international conference which led to this volume brought together leading basic scientists and clinical investigators for the purpose of coordinating the development of this new field in the fight against muscular dystrophy. The Muscular Dystrophy Association is the nation's most rapidly growing voluntary health agency in terms of its programs of patient care, research, and professional and public education. Success is attributable to its National Chairman, Jerry Lewis, to its effective corporate membership, and to the many physicians and scientists who give their time freely to advise on policies, to review grant applications, and to participate in meetings such as this. I should like to acknowledge a large number of other individuals to whom we are indebted: the broad segment of the American public which continually and generously supports our spectrum of services. The Muscular Dystrophy Association, next year, should raise in excess of $115,000,000. These contributions are derived from more than 10 million American families. These families are not only pledging their money but expressing their hopes that we will find answers to the tragic problem of neuromuscular disease. We are confident that the fruits of this meeting will move the frontier of research forward toward that goal.

Editors and Affiliations

  • University of Rochester, Rochester, USA

    Robert C. Griggs

  • McGill University, Montreal, Canada

    George Karpati

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