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Neutron Beam Design, Development, and Performance for Neutron Capture Therapy

  • Book
  • © 1990

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Editors:
  1. Otto K. Harling

    1. Nuclear Reactor Laboratory, Massachusetts Institute of Technology, Cambridge, USA

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  2. John A. Bernard

    1. Nuclear Reactor Laboratory, Massachusetts Institute of Technology, Cambridge, USA

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  3. Robert G. Zamenhof

    1. Department of Radiation Oncology, Medical Physics Division, Tufts — New England Medical Center, Boston, USA

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Part of the book series: Basic Life Sciences (BLSC, volume 54)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xi
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  2. Rapporteurs’ Report

    1. Front Matter

      Pages 1-1
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    2. Rapporteurs’ Report

      • R. M. Brugger, G. Constantine, O. K. Harling, F. J. Wheeler
      Pages 3-12

  3. Overviews of Clinical Experience, Clinical Considerations, and Tumor Targeting

    1. Front Matter

      Pages 13-13
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    2. Clinical Results of Boron Neutron Capture Therapy

      • H. Hatanaka
      Pages 15-21

    3. Clinical Considerations for Neutron Capture Therapy of Brain Tumors

      • H. Madoc-Jones, D. E. Wazer, R. G. Zamenhof, O. K. Harling, J. A. Bernard Jr.
      Pages 23-35

    4. Tumor Targeting Agents for Neutron Capture Therapy

      • A. H. Soloway, F. Alam, R. F. Barth, A. K. M. Anisuzzaman, B. V. Bapat
      Pages 37-47

  4. Neutron Beam Design

    1. Front Matter

      Pages 49-49
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    2. Monte Carlo Methods of Neutron Beam Design for Neutron Capture Therapy at the Mit Research Reactor (MITR-II)

      • S. D. Clement, J. R. Choi, R. G. Zamenhof, J. C. Yanch, O. K. Harling
      Pages 51-69

    3. Neutron Capture Therapy Beam Design at Harwell

      • G. Constantine
      Pages 71-82

    4. Physics Design for the Brookhaven Medical Research Reactor Epithermal Neutron Source

      • F. J. Wheeler, D. K. Parsons, D. W. Nigg, D. E. Wessol, L. G. Miller, R. G. Fairchild
      Pages 83-95

    5. A Calculational Study of Tangential and Radial Beams in HIFAR for Neutron Capture Therapy

      • B. V. Harrington
      Pages 97-107

    6. Research on Neutron Beam Design for BNCT at the Musashi Reactor

      • O. Aizawa
      Pages 109-124

    7. Neutron Beam Studies for a Medical Therapy Reactor

      • W. A. Neuman
      Pages 125-139

    8. Investigation of Neutron Beams for the Realization of Boron Neutron Capture Therapy

      • Gy. Csom, É. M. Zsolnay, E. J. Szondi
      Pages 141-151

    9. Intermediate Energy Neutron Beams from the MURR

      • R. M. Brugger, W. H. Herleth
      Pages 153-166

  5. Reactor-Based Neutron Beams

    1. Front Matter

      Pages 167-167
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    2. Progress Towards Boron Neutron Capture Therapy at the High Flux Reactor Petten

      • R. L. Moss
      Pages 169-183

    3. Installation and Testing of an Optimized Epithermal Neutron Beam at the Brookhaven Medical Research Reactor (BMRR)

      • R. G. Fairchild, J. Kalef-Ezra, S. K. Saraf, S. Fiarman, E. Ramsey, L. Wielopolski et al.
      Pages 185-199

    4. Neutron Capture Therapy Beams at the MIT Research Reactor

      • J. R. Choi, S. D. Clement, O. K. Harling, R. G. Zamenhof
      Pages 201-218
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Keywords

About this book

For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan between 1968 and 1989 and overviews of clinical considerations for neutron capture therapy and of the status of tumor targeting chemical agents for Ncr. Five contributed poster papers dealing with NCT beam design and performance were also presented. A rapporteurs' paper was prepared after the Workshop to attempt to summarize the major aspects, issues, and conclusions which resulted from this Workshop. Many people contributed to both the smooth functioning of the Workshop and to the preparation of these proceedings. Special thanks are reserved for Ms. Dorothy K.

Editors and Affiliations

  • Nuclear Reactor Laboratory, Massachusetts Institute of Technology, Cambridge, USA

    Otto K. Harling, John A. Bernard

  • Department of Radiation Oncology, Medical Physics Division, Tufts — New England Medical Center, Boston, USA

    Robert G. Zamenhof

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