Overview
- Editors:
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Linda L. Gallo
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The George Washington University Medical Center, USA
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Table of contents (59 chapters)
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Lipoprotein Metabolism
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- James Shepherd, Christopher J. Packard
Pages 3-8
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- S. Ferrari, E. Drusiani, P. Tarugi, S. Calandra
Pages 9-13
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- Anna M. Kessling, Philippa J. Talmud, Nazzarena Barni, Peter Carlsson, Caterina Darnfors, Gunnar Bjursell et al.
Pages 15-20
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- S. W. Law, J. C. Monge, K. J. Lackner, S. Grant, K. Higuchi, A. V. Hospattanker et al.
Pages 21-32
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- S. S. Fojo, L. Taam, S. W. Law, R. Ronan, C. Bishop, M. Meng et al.
Pages 33-50
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- Elizabeth A. Laposata, Jerome F. Strauss III, Henry M. Laboda, Jane M. Glick
Pages 51-59
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- Marcia L. Stefanick, Richard B. Terry, William L. Haskell, Peter D. Wood
Pages 61-68
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Lipoprotein Metabolism
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- Michael S. Brown, Joseph L. Goldstein
Pages 87-91
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- Richard E. Gregg, Loren A. Zech, Carlo Gabelli, Jeffrey M. Hoeg, H. Bryan Brewer Jr.
Pages 93-102
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- Henry F. Hoff, Richard E. Morton
Pages 103-119
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- Ira Tabas, George C. Boykow, David A. Weiland, Alan R. Tall
Pages 121-132
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- Gerhard A. Coetzee, Denver T. Hendricks, Wieland Gevers, Deneys R. van der Westhuyzen
Pages 145-150
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- Naphtali Savion, Aviva Gamliel
Pages 151-155
About this book
The Sixth Annual International Spring Symposium on Health Sciences, held in Washington, D. C. , in May 1986, brought together over 650 scientists from 19 countries to review and update research on cardiovascular disease. In this volume, which contains 59 chapters, an internationally recognized group of authors con tribute up-to-date accounts of molecular and cellular processes occurring in the vessel wall in atherogenesis and describe approaches to the prevention and treatment of atherosclerosis. The volume is divided into six major sections. Two sections deal with current aspects of lipoprotein metabolism. In Part I, we are alerted to the impact on li poprotein metabolism of structural heterogeneity within the four broad lipoprotein classes. Attention then turns to the components that orchestrate lipoprotein metab olism. Apolipoprotein identities, processing, and functions are described, as are the roles of lipid transfer proteins in plasma lipoprotein remodeling. Hepatic lipase synthesis and secretion are described. In Part II, Nobel Laureates Michael S. Brown and Joseph L. Goldstein describe mutations in the LDL receptor that reveal the functions of its various domains and point out how understanding the LDL receptor has provided a rational basis for its regulation. A discussion of the role of receptors in regulating cholesterol uptake by tissues follows, with emphasis on receptor-ligand interactions. Additional pathways for cholesterol delivery to cells are explored, as are pathways for cholesterol egress.
Editors and Affiliations
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The George Washington University Medical Center, USA
Linda L. Gallo
