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Genetic and Phenotypic Markers of Tumors

  • Book
  • © 1984

Overview

Editors:
  1. Stuart A. Aaronson

    1. National Cancer Institute, National Institutes of Health, Bethesda, USA

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  2. Luigi Frati

    1. Institute of General Pathology, Rome, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. Roberto Verna

    1. Institute of General Pathology, Rome, Italy

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Table of contents (35 chapters)

  1. Front Matter

    Pages i-xi
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  2. Introduction

    1. Phenotypic and Genetic Markers of Cancer: Turning Point in Research

      • Luigi Frati, Enrico Cortesi, Corrado Ficorella, Vittorio Manzari, Roberto Verna
      Pages 1-20

  3. Phenotypic Markers

    1. Biochemical Markers

      1. Multiple Biochemical Markers for Cancer: A Statistical Approach
        • Paolo Marchetti, Enrico Cortesi, Corrado Ficorella, Luigi Frati
        Pages 21-25
      2. Pseudouridine: A Biochemical Marker for Cancer
        • Filiberto Cimino, Tommaso Russo, Alfredo Colonna, Francesco Salvatore
        Pages 27-39
      3. Serum Lipid Associated Sialic Acid in Different Human Malignances: Preliminary Results
        • L. Santamaria, N. Katopodis, G. Santagati, A. Bianchi, R. Pizzala, C. C. Stock
        Pages 41-47
      4. Heterogeneity of Binding Sites for Triphenylethylene Antiestrogens in Estrogen Target Tissues
        • Alberto Gulino, Jorge Raul Pasqualini
        Pages 49-65
      5. Failure to Demonstrate Plasma Hormone Abnormalities in Women with Operable Breast Cancer
        • I. Ricciardi, S. De Placido, C. Pagliarulo, G. Delrio, F. Citarella, L. De Sio et al.
        Pages 67-74
      6. Cell-Type-Independent Accumulation of Phosphatidic Acid Induced by Trifluoperazine in Stimulated Human Platelets, Leukocytes, and Fibroblasts
        • Marco Ruggiero, Gabriella Fibbi, Mario Del Rosso, Simonetta Vannucchi, Franca Pasquali, Vincenzo Chiarugi
        Pages 75-79
      7. Protease Inhibitors in 3T3 Cells
        • Gabriella Fibbi, Vincenzo Chiarugi, Mario Del Rosso
        Pages 81-84
      8. Heterogeneity of Extramitochondrial Forms of Aspartate Aminotransferase and Malate Dehydrogenase in Yoshida Ascites Hepatoma Cells
        • Pier Paolo Gazzaniga
        Pages 85-90

    2. Detection of Antigenic Markers by Monoclonal Antibodies

      1. Biology and Immunology of Human Carcinoma Cell Populations
        • J. Schlom, D. Colcher, P. Hand, D. Wunderlich, M. Nuti, R. Mariani-Costantini et al.
        Pages 91-105
      2. Monoclonal Antibodies Against Breast Cancer
        • M. I. Colnaghi, S. Mènard, R. Mariani-Costantini, S. Canevari, S. Miotti, G. Della Torre et al.
        Pages 107-115
      3. Generation of Monoclonal Antibodies Reactive with Human Colon Carcinomas
        • Raffaella Muraro, David Wunderlich, Jeffrey Schlom
        Pages 117-127

    3. Cellular Recognition of Phenotypic Markers

      1. Reactivity of Cultured Mouse Natural Killer (NK) Cells Against Normal Non-Neoplastic Cells
        • C. Riccardi, G. Migliorati, L. Frati, F. Guadagni, E. Bonmassar, R. B. Herberman
        Pages 129-137
      2. Modulating Effects of Thymic Factors on Natural Cell-Mediated Reactivities of Natural and Cyclophosphamide-Treated Mice
        • Francesco Bistoni, Manuela Baccarini, Lucia Scaringi, Rosanna Mazzolla, Paolo Puccetti, Pierfrancesco Marconi
        Pages 139-144
      3. Effect of Inactivated <u>C. Albicans</u> on Natural Killer (NK) Cell Activity and Blastogenesis in Mice
        • Pierfrancesco Marconi, Lucia Scaringi, Antonio Cassone, Luciana Tissi
        Pages 145-151
      4. Antitumor Adjuvants from Candida Albicans : Effects on Human Allogenic T-Cell Responses “In Vitro”
        • Clara Ausiello, Giulio Spagnoli, Francesca Mondello, Pierfrancesco Marconi, Francesco Bistoni, Antonio Cassone
        Pages 153-157
      5. IL-2 and Lymphocytes from Tumor Bearing Mice: A Combinatory Immunotherapy of Tumors
        • Guido Forni, Mirella Giovarelli, Susanna Cerruti Sola, Angela Santoni
        Pages 159-173
      6. Hyporesponsiveness of Natural Killer Activity Induced in Vivo By Multiple Treatment with Maleic Acid Anhydride Divinyl Ether (MVE-2)
        • Mario Piccoli, Angela Santoni, Francesca Velotti, M. Cristina Galli, Luigi Frati, Michael A. Chirigos
        Pages 175-187
      7. Epstein-Barr Virus Markers in Nasopharyngeal Carcinoma
        • Alberto Faggioni, Giuseppe Barile, Mario Piccoli, Luigi Frati
        Pages 189-197
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Keywords

About this book

The study of tumor markers is not only one of the most important but also one that offers one of the richest perspectives in biology and clinical oncology. The aim of scientists in this field is to adduce evidence of a property that is typical of and exclusive to tumor cells, and which is easy to determine, in order to immediately recognize, or even better, to foresee, neoplastic transformations. Unfortunately, despite the large number of scientists and laboratories engaged in this work, the ideal tumor marker has not yet been identified. However, it is worth noting that new trends in molecular biology and immunovirology have recently opened up new avenues that may lead to the eventual resolution of this problem. In this book, different approaches to the identification of tumor markers, from the points of view of biochemistry, immunology, and molecular biology, are compared in order to explore possible interrelationships and to stimulate scientific collaboration among scientists active in these fields, both in basic research and in clinical applications. We wish to thank all the contributors and also the publisher, especially Dr. Robert Andrews, for making the publication of this book possible.

Editors and Affiliations

  • National Cancer Institute, National Institutes of Health, Bethesda, USA

    Stuart A. Aaronson

  • Institute of General Pathology, Rome, Italy

    Luigi Frati, Roberto Verna

Bibliographic Information

  • Book Title: Genetic and Phenotypic Markers of Tumors

  • Editors: Stuart A. Aaronson, Luigi Frati, Roberto Verna

  • DOI: https://doi.org/10.1007/978-1-4684-4856-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1984

  • Softcover ISBN: 978-1-4684-4858-0Published: 30 March 2012

  • eBook ISBN: 978-1-4684-4856-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 380

  • Topics: Immunology

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