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Human Trophoblast Neoplasms

  • Book
  • © 1984

Overview

Editors:
  1. Roland A. Pattillo

    1. Department of Gynecology and Obstetrics, The Medical College of Wisconsin, Milwaukee, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Robert O. Hussa

    1. Department of Gynecology and Obstetrics, The Medical College of Wisconsin, Milwaukee, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 176)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-x
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  3. Immunology, Gestation, and Neoplasia

    1. Front Matter

      Pages 51-52
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    2. Genetic Origin, Immunobiology, and Gonadotropin Expression in Trophoblast and Nontrophoblast Neoplasms

      • Roland A. Pattillo
      Pages 53-79

    3. Immunology in Genesis of Partial and Total Hydatidiform Mole

      • Shoshichi Takeuchi
      Pages 81-110

    4. Complement System in Abnormal Pregnancy and Chorionic Neoplasia: Immunotherapy and Chemotherapy of Chorionic Neoplasia

      • Ryoki Ohkawa, Kimiyasu Ohkawa, Norio Tosaka, Toshikatsu Ohhashi, Akira Hatano, Tsutomu Ohkawa
      Pages 111-125

    5. Placental Senescence

      • Tim Parmley
      Pages 127-132

  4. Genetic Origin of Trophoblast Neoplasms

    1. Front Matter

      Pages 133-133
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    2. Complete and Partial Hydatidiform Moles: Cytogenetic and Morphological Aspects

      • A. E. Szulman, Urvashi Surti
      Pages 135-146

    3. Genetic Studies on Hydatidiform Moles

      • Sylvia D. Lawler
      Pages 147-161

  5. Epidemiologic Aspects of Trophoblastic Neoplasms

    1. Front Matter

      Pages 163-163
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    2. Epidemiology of Gestational Trophoblastic Neoplasm at the Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia

      • M. Farid Aziz, Nugroho Kampono, Endy Muhardin Moegni, Sjahrul Sjamsuddin, Budianto Barnas, Ratna Suprapti Samil
      Pages 165-175

    3. Epidemiologic Aspects of Gestational Trophoblastic Diseases in Ibadan, Nigeria

      • T. A. Junaid
      Pages 177-185

    4. Epidemiology of Trophoblast Disease in Africa — Lagos

      • Akin Agboola, O. O. Abudu
      Pages 187-195

  6. Human Chorionic Gonadotropin

    1. Front Matter

      Pages 197-197
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    2. Immunochemistry of Human Chorionic Gonadotropin

      • R. E. Canfield, S. Birken, P. Ehrlich, G. Armstrong
      Pages 199-215

    3. New Horizons in hCG Detection

      • Robert Hussa, Laurence A. Cole
      Pages 217-243

    4. The Carbohydrate on Human Chorionic Gonadotropin Produced by Cancer Cells

      • Laurence A. Cole, Robert O. Hussa
      Pages 245-270
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Keywords

About this book

This book addresses neoplasms of the human trophoblast. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries. The stimulus for the book evolved out of a common interest to combine Western technology with the clinical experience in the developing world in a common pursuit of the study and eradication of trophoblast neoplasia. There is substantial evidence to contend that gene derepression as seen in trophoblastic disease may be a universal prerequisite to neoplastic transformation in general. The recent discovery that the tumor markers, human chorionic gonadotropin (hCG) or its subunits, are identifiable in over 90 percent of all extracted neoplasms suggests a critical role for this common denominator of gene derepression in neoplasia. This gene derepression concept in reproductive biology and neoplasia spans many of the basic parameters of human cell replication as related to endocrinology, immunology, biochemistry, electrophysiol­ ogy, genetics, and pharmacology. The International Society for the Study of Trophoblastic Disease focuses on the global aspects of trophoblast neoplasms. These global aspects include epidemiology and etiology of the disease, regional variations in treatment of trophoblastic neoplasms, and potential ways to adapt and apply Western technology to effective use in developing countries. It was this perspective that formed the basis for the First World Congress on Trophoblast Neoplasms, which convened in Nairobi in October, 1982.

Editors and Affiliations

  • Department of Gynecology and Obstetrics, The Medical College of Wisconsin, Milwaukee, USA

    Roland A. Pattillo, Robert O. Hussa

Bibliographic Information

  • Book Title: Human Trophoblast Neoplasms

  • Editors: Roland A. Pattillo, Robert O. Hussa

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-4811-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1984

  • Softcover ISBN: 978-1-4684-4813-9Published: 25 November 2012

  • eBook ISBN: 978-1-4684-4811-5Published: 13 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 505

  • Topics: Oncology

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