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Porphyrins in Tumor Phototherapy

  • Book
  • © 1984

Overview

Editors:
  1. Alessandra Andreoni

    1. The Polytechnic Institute of Milan, National Research Council, Milan, Italy

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  2. Rinaldo Cubeddu

    1. The Polytechnic Institute of Milan, National Research Council, Milan, Italy

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (50 chapters)

  1. Front Matter

    Pages i-xii
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  2. Physics and Chemistry of Porphyrins and Related Compounds

    1. Front Matter

      Pages 1-1
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    2. Excited State Properties of Haematoporphyrin

      • R. Brookfield, M. Craw, C. R. Lambert, E. J. Land, R. Redmond, R. S. Sinclair et al.
      Pages 3-10

    3. Fluorescence Properties of HpD and its Components

      • Alessandra Andreoni, Rinaldo Cubeddu
      Pages 11-21

    4. The Structure of the Active Component of Hematoporphyrin Derivative

      • T. J. Dougherty, W. R. Potter, K. R. Weishaupt
      Pages 23-35

    5. Photophysical and Photosensitizing Properties of Photofrin II

      • A. Poletti, S. M. Murgia, A. Pasqua, E. Reddi, G. Jori
      Pages 37-43

    6. On the Purification of Hematoporphyrin IX and its Acetylated Derivatives

      • Daniel Brault, Christine Bizet, Olavio Delgado
      Pages 45-49

    7. Photosensitizing Properties of Porphyrins in Model Cell Systems

      • John D. Spikes
      Pages 51-60

    8. Photosensitizing Properties of Free and Bound Uroporphyrin I

      • John D. Spikes, Bruce F. Burnham, Jerry C. Bommer
      Pages 61-65

    9. Chemical and Biological Studies on Haematoporphyrin Derivative: An Unexpected Photosensitisation in Brain

      • R. Bonnett, M. C. Berenbaum, H. Kaur
      Pages 67-80

    10. A Chromatographic Study of Hematoporphyrin Derivatives

      • Stein Sommer, Johan Moan, Terje Christensen, Jan F. Evensen
      Pages 81-91

    11. Protection by Carotenoids from Singlet Oxygen Photoproduced by Porphyrins

      • R. V. Bensasson, T. A. Moore, D. Gust, A. L. Moore, A. Joy, T. Tom et al.
      Pages 93-94

    12. Effect of He-Ne Laser on Human Erythrocytes Incubated with Hematoporphyrin Derivative and Bonellin: Comparative Study

      • G. Monfrecola, D. Martellotta, R. Galli, G. Bruno, L. Cariello, L. Zanetti et al.
      Pages 95-99

    13. Survey of Potential PRT Dyes and their Spectroscopic Properties

      • Fred M. Johnson, Joseph F. Becker
      Pages 101-105

  3. Interactions of Porphyrins with Model Systems and Cells

    1. Front Matter

      Pages 107-107
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    2. Fluorescence of Porphyrins in Cells

      • Johan Moan
      Pages 109-124

    3. Hematoporphyrin Derivative: Fluorometric Studies in Solution and Cells

      • Giovanni Bottiroli, Franco Doccio, Isabel Freitas, Roberta Ramponi, Carlo Alberto Sacchi
      Pages 125-136

    4. Time-Resolved Laser Fluorescence and Photobleaching of Single Cells after Photosensitization with Hematoporphyrin Derivative (HpD)

      • H. Schneckenburger, E. Unsöld, W. Weinsheimer, D. Jocham
      Pages 137-141

    5. Effects of HpD and Laser on Transformed and Corresponding Normal Cultured Cells: Differential Cytotoxicity as an in Vitro Model for Tumor Photochemotherapy

      • Francesco Saverio Ambesi-Impiombato, Alessandra Andreoni, Rinaldo Cubeddu, Mario Esposito, Michele Mastrocinque, Donatella Tramontano
      Pages 143-155

    6. Interaction of Free and Liposome-Bound Porphyrins with Normal and Malignant Cells: Biochemical and Photosensitization Studies in Vitro and in Vivo

      • I. Cozzani, G. Jori, E. Reddi, L. Tomio, P. L. Zorat, T. Sicuro et al.
      Pages 157-165
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Keywords

About this book

This book contains the contributions of the participants to the International Symposium on Porphyrins in Tumor Phototherapy held in Bruzzano (Milano), Italy on May 26-28, 1983. The contributions are written as extended papers to provide a broad and representative coverage of the use of porphyrins in tumor phototherapy and diagnosis. In the last few years, this technique has received increasing interest for its potential applications in clinical oncology. In fact, 1,500 patients have been already treated by this therapy which has been tested in more than 100 clinical centres. Among the reported cases, a significant therapeutic effectiveness was found in some early stage cancers of lung, esophagus and stomach. The development of ·this therapy requires interdisciplinary studies from such diverse fields as physics, chemistry, biology, pharmacology, and experimental and clinical oncology. The contents of the book reflect the character of this research and deal with all the problems, from fundamental to clinical, that still require to be analysed and understood for a better evaluation 'of the potential of this therapy. The first chapter of the book deals with photophysics ?;nd.

Editors and Affiliations

  • The Polytechnic Institute of Milan, National Research Council, Milan, Italy

    Alessandra Andreoni, Rinaldo Cubeddu

Bibliographic Information

  • Book Title: Porphyrins in Tumor Phototherapy

  • Editors: Alessandra Andreoni, Rinaldo Cubeddu

  • DOI: https://doi.org/10.1007/978-1-4684-4721-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1984

  • Softcover ISBN: 978-1-4684-4723-1Published: 25 November 2012

  • eBook ISBN: 978-1-4684-4721-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 466

  • Topics: Science, Humanities and Social Sciences, multidisciplinary

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