Genetic Control of Environmental Pollutants

1. Front Matter

   Pages i-x

   PDF

2. Welcome and Introduction

   1. Welcome and Introduction

      • Gilbert S. Omenn

      Pages 1-2

3. Environmental Toxicants

   1. Microbial Biodegradation of 2,4,5-Trichlorophenoxyacetic Acid and Chlorophenols

      • J. S. Karns, J. J. Kilbane, D. K. Chatterjee, A. M. Chakrabarty

      Pages 3-21

   2. Bacterial Transformations of and Resistances to Heavy Metals

      • Simon Silver, Tapan K. Misra

      Pages 23-46

   3. The Identification and Cloning of Genes Encoding Haloaromatic Catabolic Enzymes and the Construction of Hybrid Pathways for Substrate Mineralization

      • A. J. Weightman, R. H. Don, P. R. Lehrbach, K. N. Timmis

      Pages 47-80

   4. General Discussion: Environmental Toxicants

      • A. M. Chakrabarty, Gilbert S. Omenn, Simon Silver, Andrew Weightman

      Pages 81-90

4. Engineering Organisms to Survive

   1. Engineering Organisms to Survive Introduction

      • Morris Levin, Mark Segal

      Pages 91-95

   2. Biodegradation in the Estuarine-Marine Environments and the Genetically Altered Microbe

      • Al W. Bourquin

      Pages 97-115

   3. Plasmid-Mediated Biodegradative Fate of Monohalogenated Biphenyls in Facultatively Anaerobic Sediments

      • Gary S. Sayler, Hay-Long Kong, Malcolm S. Shields

      Pages 117-135

   4. Land Disposal and Spill Site Environments

      • A. C. Middleton

      Pages 137-149

   5. Ecological Constraints on Genetic Engineering

      • Martin Alexander

      Pages 151-168

   6. Panel Discussion: Vulnerability of Ecosystems

      • A. M. Chakrabarty, Rita Colwell, Gordon H. Orians, James A. Shapiro, James Staley, Andrew Weightman

      Pages 169-186

5. Enviromental Waste Streams

   1. Perspective on Opportunities for Genetic Engineering Applications in Industrial Pollution Control

      • James W. Patterson

      Pages 187-193

   2. Application of Genetic Engineering to Industrial Waste/Wastewater Treatment

      • Hester A. Kobayashi

      Pages 195-214

   3. Needs and Strategies for Genetic Control: Municipal Wastes

      • Bruce E. Rittmann

      Pages 215-228

   4. Pseudomonas Hydrocarbon Oxidation

      • J. A. Shapiro, D. J. Owen, M. Kok, G. Eggink

      Pages 229-238

   5. Microbial Enzymes and Lignocellulose Utilization

      • Ross D. Brown Jr., Mikelina Gritzali

      Pages 239-265

   6. Panel Discussion: Comparison of Traditional and Genetic Strategies

      • Ross D. Brown Jr., Joel S. Hirschhorn, Hester A. Kobayashi, Joseph L. McCarthy, James W. Patterson, Bruce E. Rittmann et al.

      Pages 267-273

6. Diverse Capabilities of Microorganisms

   1. Diverse Capabilities of Microorganisms Introduction

      • Eugene Nester

      Pages 275-276

   2. Capabilities of Microorganisms (and Microbiologists)

      • Arnold L. Demain

      Pages 277-299

Gilbert S. Omenn Dean, Public Health and Community Medicine University of Washington Seattle, Washington 98195 On behalf of the University of Washington, the City of Seattle, the sponsors and donors, and my co-organizers, I am delighted to welcome all of you to this Conference on Genetic Control of Environ­ mental Pollutants. My only regret is that Dr. Alexander Hollaender, who has inspired so many of us as young scientists and stimulated so many trail-blazing conferences in environmental sciences and in gen­ etic engineering, is ill and was unable to make the trip to Seattle. He sends his warm good wishes for an outstanding meeting and a fine volume. The purpose of this Conference is to identify and assess strat­ egies for more effectively and safely managing wastes and toxic sub­ stances in the environment, in part through use of genetically engi­ neered microorganisms. There is a sense of desperation in our soci­ ety that modern technologies have introduced a bewildering array of potential hazards to human health and to our environment. There is an accompanying sense of frustration that our prodigious basic re­ search capabilities and our technological ingenuity have not yielded practical ways to control many pollutants and waste streams, or-­ better still--to convert them to useful products.

• cellulose
• cloning
• genetic engineering
• heavy metals
• Tree Biology

• University of Washington, Seattle, USA

  Gilbert S. Omenn

• Associated Universities, Inc., USA

  Alexander Hollaender

Policies and ethics