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Composition and Function of Cell Membranes

Application to the Pathophysiology of Muscle Diseases

  • Book
  • © 1981

Overview

Editors:
  1. Stewart Wolf

    1. St. Luke’s Hospital, Bethlehem, USA
      Temple University, Philadelphia, USA
      Scientific Advisory Committee, Muscular Dystrophy Association, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Allen K. Murray

    1. Muscular Dystrophy Association, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 140)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xi
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  2. Phylogeny, Structure and Composition of Cell Membranes

    • Stewart Wolf, Allen K. Murray
    Pages 1-53

  3. Characteristics and Behavior of Plasma Membranes

    • Stewart Wolf, Allen K. Murray
    Pages 55-106

  4. Regulation of Membrane Functions

    • Stewart Wolf, Allen K. Murray
    Pages 107-135

  5. The Lipid Bilayer, Mechanisms of Fusion and Transmembrane Transport

    • Stewart Wolf, Allen K. Murray
    Pages 137-186

  6. Membrane Alterations in Erythrocytes and Cultured Fibroblasts in Neuromuscular Diseases

    • Stewart Wolf, Allen K. Murray
    Pages 187-210

  7. Abnormalities in Muscle in Duchenne Muscular Dystrophy

    • Stewart Wolf, Allen K. Murray
    Pages 211-259

  8. Back Matter

    Pages 261-287
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Keywords

About this book

The present volume contains the edited transcript of a Totts Gap Colloquium held May 19-21, 1980 sponsored by the Muscular Dystrophy Association. The aim of the colloquium was to bring into focus data relating to cell membranes that might contribute to understanding the pathogenic mechanism of Duchenne muscular dystrophy. A major impediment to progress in understanding the patho­ genesis of muscular dystrophy has been the failure, so far, to identify the basic genetic defect. Pending the identification of the genetic lesion in Duchenne dystrophy and, in view of scattered but persistent indications of a basic membrane disturbance, it seemed worthwhile to explore in open dialogue the current state of knowledge of membrane morphology and chemistry with an eye to possible leads for further investigation. The participants, drawn from a variety of interested disciplines, attempted to synthesize and reconcile their findings and to identify crucial areas of ignorance in need of exploration. For the most part they avoided specialized jargon and spoke in a language that could be understood by the rest of the group. Apart from providing a review of widely varying approaches to the study of the composition and behavior of cell membranes, the discussions brought together current think~g on strategies and approaches to the study of the pathogenesis of muscular dystrophy. Already the personal contacts made at the colloquium have led to new inter-institutional collabora­ tive investigations.

Editors and Affiliations

  • St. Luke’s Hospital, Bethlehem, USA

    Stewart Wolf

  • Temple University, Philadelphia, USA

    Stewart Wolf

  • Scientific Advisory Committee, Muscular Dystrophy Association, USA

    Stewart Wolf

  • Muscular Dystrophy Association, New York, USA

    Allen K. Murray

Bibliographic Information

  • Book Title: Composition and Function of Cell Membranes

  • Book Subtitle: Application to the Pathophysiology of Muscle Diseases

  • Editors: Stewart Wolf, Allen K. Murray

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-4112-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1981

  • Softcover ISBN: 978-1-4684-4114-7Published: 25 February 2012

  • eBook ISBN: 978-1-4684-4112-3Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 287

  • Topics: Cell Biology, Pathology, Neurology

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