Neuroendocrinology of Reproduction

1. Front Matter

   Pages i-xxi

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2. Chemical Background of Endocrine Function

   1. Front Matter

      Pages 1-1

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   2. Structure of Protein and Peptide Hormones

      • Bruce D. Goldman

      Pages 3-12

   3. Histology of the Pituitary

      • Bruce D. Goldman

      Pages 13-17

   4. Essentials of Steroid Structure, Nomenclature, Reactions, Biosynthesis, and Measurements

      • Harvey H. Feder

      Pages 19-63

   5. Neurotransmitter Systems

      • William R. Crowley, Frank P. Zemlan

      Pages 65-85

3. Development of Reproductive Function

   1. Front Matter

      Pages 87-87

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   2. Hormonal Actions on the Sexual Differentiation of the Genitalia and the Gonadotropin-Regulating Systems

      • Harvey H. Feder

      Pages 89-126

   3. Perinatal Hormones and Their Role in the Development of Sexually Dimorphic Behaviors

      • Harvey H. Feder

      Pages 127-157

   4. Early Organizational Effects of Hormones

      • Elizabeth Adkins-Regan

      Pages 159-228

   5. Puberty

      • Bruce D. Goldman

      Pages 229-239

4. Control of Reproduction on the Organismic and Physiological Levels of Organization

   1. Front Matter

      Pages 241-241

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   2. Experimental Analysis of Hormone Actions on the Hypothalamus, Anterior Pituitary, and Ovary

      • Harvey H. Feder

      Pages 243-278

   3. Estrous Cyclicity in Mammals

      • Harvey H. Feder

      Pages 279-348

   4. How the Brain Mediates Ovarian Responses to Environmental Stimuli

      • B. R. Komisaruk, E. Terasawa, J. F. Rodriguez-Sierra

      Pages 349-376

   5. Seasonal Reproduction

      • Jeffrey A. Elliott, Bruce D. Goldman

      Pages 377-423

5. Control of Reproduction on the Cellular and Chemical Level

   1. Front Matter

      Pages 425-425

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   2. CNS Control of the Pituitary

      • Samuel McCann

      Pages 427-450

   3. The Neurochemical Control of Mating Behavior

      • William R. Crowley, Frank P. Zemlan

      Pages 451-484

   4. Cellular Biochemistry of Hormone Action in Brain and Pituitary

      • Bruce S. McEwen

      Pages 485-518

The subject of this book is neuroendocrinology, that branch of biological science devoted to the interactions between the two major integrative organ systems of animals-the endocrine and nervous systems. Although this science today reflects a fusion of endocrinology and neurobiology, this synthetic ap­ proach is relatively recent. At the beginning of the 20th century, when the British physiologists, Bayliss and Starling, first proposed endocrinology to be an independent field of inquiry, they went to great lengths to establish the autonomy of chemical secretions in general and their independence from nervous control in particular (Bayliss, W. M. , and Starling, E. H. , 1902, The mechanism of pancreatic secretion,]. Physiol. 28:325). They argued with Pav­ lov, who said that there was a strong influence of the nervous system on the gastrointestinal phenomena the endocrinologists were studying. For several decades, the English physiologists prevailed, at least in the West; and Pavlov's critique was not taken to heart by the practitioners of the newly emerging discipline of endocrinology. Through the work of Harris, the Scharrers, Sawyer, Everett, and others, there has been something of a scientific detente in the latter half of this century; the hybrid field of neuroendocrinology is now regarded as one of the corner­ stones of modern neural science and is of fundamental importance in basic and clinical endocrinology.

• endocrinology
• nervous system
• neurobiology
• neuroendocrinology
• reproduction

• University of Pennsylvania, Philadelphia, USA

  Norman T. Adler

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