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Serotonin

Current Aspects of Neurochemistry and Function

  • Book
  • © 1981

Overview

Editors:
  1. Bernard Haber

    1. The University of Texas Medical Branch, Galveston, USA

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  2. Sabit Gabay

    1. Veterans Administration Medical Center, Brockton, USA
      Brown University Division of Psychiatry and Human Behavior, Providence, USA

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  3. M. R. Issidorides

    1. University of Athens School of Medicine, Athens, Greece

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  4. S. G. A. Alivisatos

    1. University of Athens School of Medicine, Athens, Greece

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 133)

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Table of contents (43 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Neuroanatomy of Serotonergic and Related Systems

    1. Front Matter

      Pages 1-5
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    2. Localization of Serotonin-Like Immunoreactivity in the Central Nervous System and Pituitary of the Rat, with Special References to the Innervation of the Hypothalamus

      • H. W. M. Steinbusch, R. Nieuwenhuys
      Pages 7-35

    3. Serotonin Binding Protein: Role in Transmitter Storage in Central and Peripheral Serotonergic Neurons

      • Michael D. Gershon, Hadassah Tamir
      Pages 37-49

    4. Radioautographic Investigation of Serotonin Cells

      • André Calas, Jean-Jacques Dupuy, Halima Gamrani, Jean Gonella, Christiane Mourre, Madeleine Condamin et al.
      Pages 51-66

    5. Anatomical Evidence for GABA-5 HT Interaction in Serotonergic Neurons

      • Jean-François Pujol, Marie-Françoise Belin, Halima Gamrani, Michèle Aguera, André Calas
      Pages 67-79

    6. Evidence for the Coexistence of Serotonin and Substance P in Single Raphe Cells and Fiber Plexuses: Combined Immunocytochemistry and Autoradiography

      • Victoria Chan-Palay
      Pages 81-97

  3. Role of Serotonin in Processing of Nociceptive Information

    1. Front Matter

      Pages 99-104
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    2. Effects of Peripherally and Centrally Administered Serotonin on Primate Spinothalamic Neurons

      • W. D. Willis
      Pages 105-123

    3. The Role of Serotonin in Modulation of Nociceptive Reflexes

      • John A. Harvey, Kenny J. Simansky
      Pages 125-151

    4. Role of the Raphe Nuclei in Stimulation Producing Analgesia

      • Jean-Marie Besson, Jean-Louis Oliveras, Athmane Chaouch, Jean-Paul Rivot
      Pages 153-176

    5. Descending Control of Pain Transmission: Possible Serotonergic-Enkephalinergic Interactions

      • Allan I. Basbaum
      Pages 177-189

  4. The Regulation of Synthesis

    1. Front Matter

      Pages 191-195
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    2. Synthesis and Quantitative Aspects of Dihydrobiopterin Control of Cerebral Serotonin Levels

      • E. Martin Gál
      Pages 197-206

    3. Influence of Plasma Tryptophan on Brain 5HT Synthesis and Serotonergic Activity

      • G. Curzon
      Pages 207-219

    4. Tryptophan Availability and the Control of 5-Hydroxytryptamine and Tryptamine Synthesis in Human CNS

      • Simon N. Young, Serge Gauthier
      Pages 221-230

    5. Regulatory Properties of Neuronal Tryptophan Hydroxylase

      • Michel Hamon, Sylvie Bourgoin, Françoise Artaud, David Nelson
      Pages 231-251

    6. Studies on the Oxygen Sensitivity of Tryptophan Hydroxylase

      • Donald M. Kuhn, Belle Ruskin, Walter Lovenberg
      Pages 253-263

    7. Influence of Histamine on Serotonin Metabolism in Rat Brain

      • Czeslaw Maslinksi, Jerzy Z. Nowak
      Pages 265-275

    8. Serotonin and Dopamine Synthesis in Phenylketonuria

      • H.-Ch. Curtius, A. Niederwieser, M. Viscontini, W. Leimbacher, H. Wegmann, B. Blehova et al.
      Pages 277-291
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Keywords

About this book

The vast growth of knowledge in recent years concerning the functional role of serotonergic systems in central nervous system function prompted the organization of the symposium. The organiz­ ing committees felt at the onset that the field of serotonin research had grown so rapidly that it would be impossible to cover every aspect of it in individual symposia. Thus it was felt that certain areas of research had to be omitted due to time constraints, and we extend an apology to the researchers in areas not included in these proceedings. Rather it was hoped to provide a balance overview of the field, starting with the anatomy of serotonergic systems and proceeding to the level of the serotonergic receptors at the cell membrane, and then inside the neuron to discuss the regulation of serotonin bisynthesis and integration within indole­ mine systems. The functional aspects of serotonergic transmission focused on the emerging role of this amine in the processing of nociceptive information, singly or in tandem with other neurotran­ smitters or neuromodulators. A separate symposium dealt with a variety of animal models suitable for the analysis of the role of serotonin in behavior, and finally led to the evaluation of serotonin metabolism in the study of abnormal human behavior. The editors would like to dedicate these proceedings on /Serotonin - Current Aspects of Neurochemistry and Function/ to two pioneers in this field, Dr. Irving Page and Dr. Maurice Rapport.

Editors and Affiliations

  • The University of Texas Medical Branch, Galveston, USA

    Bernard Haber

  • Veterans Administration Medical Center, Brockton, USA

    Sabit Gabay

  • Brown University Division of Psychiatry and Human Behavior, Providence, USA

    Sabit Gabay

  • University of Athens School of Medicine, Athens, Greece

    M. R. Issidorides, S. G. A. Alivisatos

Bibliographic Information

  • Book Title: Serotonin

  • Book Subtitle: Current Aspects of Neurochemistry and Function

  • Editors: Bernard Haber, Sabit Gabay, M. R. Issidorides, S. G. A. Alivisatos

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-3860-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1981

  • Softcover ISBN: 978-1-4684-3862-8Published: 27 December 2012

  • eBook ISBN: 978-1-4684-3860-4Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVI, 824

  • Topics: Neurosciences

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