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Current Trends in Histocompatibility

Volume 2 Biological and Clinical Concepts

  • Book
  • © 1981

Overview

Editors:
  1. Ralph A. Reisfeld

    1. Scripps Clinic and Research Foundation, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Soldano Ferrone

    1. Scripps Clinic and Research Foundation, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Role of Histocompatibility Antigens in Cell-Cell Interaction

    1. Front Matter

      Pages 1-1
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    2. Histocompatibility Antigens and the T-Cell Repertoire

      • Harald von Boehmer
      Pages 3-18

    3. Continuously Proliferating Allospecific T-Cell Lines

      • Gunther Dennert
      Pages 19-34

    4. The Dual Specificity of Virus-Immune T Cells

      • Peter C. Doherty, Jack R. Bennink, Rita B. Effros, Mark Frankel
      Pages 35-57

    5. Hapten Recognition by Cytotoxic T Cells

      • Christopher S. Henney, Zuhair K. Ballas, Keiko Ozato
      Pages 59-80

    6. New Thoughts on the Control of Self-Recognition, Cell Interactions, and Immune Responsiveness by Major Histocompatibility Complex Genes

      • David H. Katz
      Pages 81-103

    7. The Role of Cell-Surface Antigens in Progressive Tumor Growth (Immunological Surveillance Re-revisited)

      • Lionel A. Manson
      Pages 105-112

    8. Self-HLA-D-Region Products Restrict Human T-Lymphocyte Activation by Antigen

      • E. Thorsby, B. Bergholtz, H. Nousiainen
      Pages 113-141

    9. How Strict Is the MHC Restriction of T Cells?

      • Rolf M. Zinkernagel
      Pages 143-155

  3. Clinical Aspects of Transplantation: Association with Disease

    1. Front Matter

      Pages 157-157
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    2. The Role of Histocompatibilty Antigens in Clinical Transplantation

      • Kent C. Cochrum, Deanne M. Hanes
      Pages 159-175

    3. HLA-Linked Regulation of Immune Responsiveness in Man

      • Leonard J. Greenberg
      Pages 177-199

    4. Clinical Histocompatibility Testing in Renal Transplantation

      • Ronald H. Kerman, Barry D. Kahan
      Pages 201-226

    5. Human Ia-like Alloantigens and Their Medical Significances

      • Faramarz Naeim, Roy L. Walford
      Pages 227-256

    6. The Enigma of Good Kidney-Graft Survival in the Face of Poor HLA Matches

      • J. J. van Rood, G. G. Persijn, E. Goulmy, B. A. Bradley
      Pages 257-278

    7. Histocompatibility Antigens and Susceptibility to Disease—Genetic Considerations

      • Lars P. Ryder, Per Platz, Arne Svejgaard
      Pages 279-301

  4. Back Matter

    Pages 303-311
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Keywords

About this book

Information about histocompatibility antigens is expanding so rapidly that of all advances. In these volumes, we have it is difficult to remain abreast made an effort to bring together the most current work on topics that have generated most of the recent advances and discussions. We have asked each author to present and interpret his most current work, and we have judiciously refrained from imposing our own prejudices and viewpoints. Although there is obvious overlap in some individual topics, we have encouraged this to provide the reader with as many different and some­ times opposing viewpoints as possible. This approach will, we hope, give a broad overview of current ideas in the field. We wish to thank all contributors for their timely and exciting manu­ scripts, and we sincerely hope that the reader will benefit from these volumes. R. A. Reisfeld S. Ferrone La Jolla vii Contents I. Role of Histocompatibility Antigens in Cell-Cell Interaction Chapter 1 Histocompatibility Antigens and the T-Cell Repertoire . . . . . . . . . . . . . . 3 Harald von Boehmer 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. H-2 Restriction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 1. H-2 Restriction of T Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 2. B Cells Are Not H-2-Restricted . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3. H-2-Linked Ir Genes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3. 1. Influence on the T-Cell Repertoire . . . . . . . . . . . . . . . . . . . . . . . . 5 3. 2. H-2-Gene Complementation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3. 3. The B-Cell Repertoire Is Not Directly Influenced by H-2-Linked Ir Genes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. Frequency of Cells Specific for Allogeneic H-2 Antigens . . . . . . . . 12 4. 1. Allospecific T Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. 2. Allospecific B Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Editors and Affiliations

  • Scripps Clinic and Research Foundation, La Jolla, USA

    Ralph A. Reisfeld, Soldano Ferrone

Bibliographic Information

  • Book Title: Current Trends in Histocompatibility

  • Book Subtitle: Volume 2 Biological and Clinical Concepts

  • Editors: Ralph A. Reisfeld, Soldano Ferrone

  • DOI: https://doi.org/10.1007/978-1-4684-3761-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1981

  • Softcover ISBN: 978-1-4684-3763-8Published: 16 September 2012

  • eBook ISBN: 978-1-4684-3761-4Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XVI, 311

  • Topics: Immunology

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