Secretory Immunity and Infection

1. Front Matter

   Pages i-xxi

   PDF

2. Introductory Address

   1. New Areas Arising from Studies of Secretory Immunity

      • Thomas B. Tomasi Jr.

      Pages 1-8

3. Cellular Aspects of Mucosal Immunity

   1. Generation of Clonal and Isotype Diversity

      • Max D. Cooper, Hiromi Kubagawa, Larry B. Vogler, John F. Kearney, Alexander R. Lawton

      Pages 9-17

   2. Cellular Parameters of the IgA Response

      • John J. Cebra, Rebecca Emmons, Patricia J. Gearhart, Stella M. Robertson, Jeenan Tseng

      Pages 19-28

   3. Lymphatic Physiology and Secretory Immunity

      • Joe Hall, Eva Orlans, Jane Peppard, John Reynolds

      Pages 29-34

   4. Development of the IgA System in the Mammary Gland

      • Michael E. Lamm, Paul Weisz-Carrington, M. Estela Roux, Michael McWilliams, Julia M. Phillips-Quagliata

      Pages 35-42

   5. Effect of Anti-IgD Serum on Immune Responses

      • R. M. E. Parkhouse, D. W. Dresser

      Pages 43-51

   6. A Common Mucosal Immunologic System Involving the Bronchus, Breast and Bowel

      • John Bienenstock, Mark McDermott, Dean Befus, Michael O’Neill

      Pages 53-59

   7. Discussion

      • Jerry R. McGhee, Jiri Mestecky, James L. Babb

      Pages 61-66

   8. Migration Pathways of T Lymphocytes in the Small Intestine

      • Delphine M. V. Parrott, Marlene L. Rose

      Pages 67-74

   9. Cell-Mediated Immunity on Secretory Surfaces

      • Rama Ganguly, Robert H. Waldman

      Pages 75-85

   10. Immunoglobulin a Production by Human Colostral Cells: Quantitative Aspects

       • Randall M. Goldblum, Jay Van Bavel

       Pages 87-94

   11. Immunologic Aspects of Human Colostrum and Milk: Interaction with the Intestinal Immunity of the Neonate

       • S. S. Ogra, D. I. Weintraub, P. L. Ogra

       Pages 95-107

   12. Discussion

       • Jerry R. McGhee, Jiri Mestecky, James L. Babb

       Pages 109-112

4. Induction of a Secretory Immune Response

   1. Remote-Site Stimulation of Secretory IgA Antibodies Following Bronchial and Gastric Stimulation

      • Paul C. Montgomery, Kevin M. Connelly, Judith Cohn, Cheryl A. Skandera

      Pages 113-122

   2. Development of Humoral Antibody Following the Ingestion of Soluble Protein Antigen by Passively Immunized Animals

      • Richard M. Rothberg, Christian H. L. Rieger, Sumner C. Kraft, James V. Lustig

      Pages 123-132

   3. Elimination of Escherichia Coli K88 Adhesion Determinant by Antibody in Porcine Gut and Mammary Secretions Following Oral Immunization

      • Philip Porter, Margaret A. Linggood, John Chidlow

      Pages 133-142

   4. Cellular Aspects of the Murine Anti-Hapten IgA Response

      • Edward T. Lally, Ian M. Zitron, Richard C. Fiorini, Paul C. Montgomery

      Pages 143-150

   5. Discussion

      • Jerry R. McGhee, Jiri Mestecky, James L. Babb

      Pages 151-154

   6. Characterization of Immunoglobulin-Containing Cells in the Submandibular Gland of the Rat after Local Immunization

      • Jeffrey L. Ebersole, Martin A. Taubman, Daniel J. Smith, John M. Crawford

      Pages 155-164

The present conference is the third in a series on this topic sponsored by the NCP. Drs. HcGhee, l1estecky, Genco and Bowen are to be commended for arranging this truly comprehensive program. We are fortunate that they have been able to assemble such a wealth of expertise. Program staff considers the advice of scientists such as yourselves essential to the success of its mission. Your presentations and discussions will focus on the crucial problems to be solved in exploiting the secretory immune system to combat dental caries. The published proceedings will bring these to the attention of the research community quickly and hopefully they will stimulate new investigators to bring their talents to these problems. This meeting will, to a large extent, determine the direction of research sponsored by the NCP. Finally, I would like to thank the members of the planning committee for their dedicated efforts over the past two years, which have culminated in this symposium. Our thanks are also due to each of you, in advance, for contributing so freely to the success of this meeting.

• antibody
• antigen
• bacteria
• diseases
• immune response
• immune system
• immunity
• immunization
• immunodeficiency
• immunoglobulin
• infection
• lymphocytes
• physiology
• proteins
• research

• Institute of Dental Research, Departments of Microbiology and Medicine, Comprehesive Cancer Center, University of Alabama in Birmingham, Birmingham, USA

  Jerry R. McGhee, Jiri Mestecky, James L. Babb

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