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Contemporary Topics in Immunobiology

Volume 3

  • Book
  • © 1974

Overview

Editors:
  1. M. G. Hanna

    1. Oak Ridge National Laboratory, Oak Ridge, USA

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  2. Max D. Cooper

    1. University of Alabama, Birmingham, USA

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  3. Noel L. Warner

    1. The Walter and Eliza Hall Institute, Australia

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiv
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  2. T Cell Control of Antibody Production

    • Richard K. Gershon
    Pages 1-40

  3. Short-Term and Chronic Allotype Suppression in Mice

    • Leonore A. Herzenberg, Leonard A. Herzenberg
    Pages 41-75

  4. On the Relationship Between Cellular and Humoral Antibodies

    • Hans Wigzell
    Pages 77-96

  5. T Cell Modification of B Cell Responses to Antigen in Mice

    • Graham F. Mitchell
    Pages 97-116

  6. Genetic Control of Antibody Responses to Myeloma Proteins of Mice

    • Rose Lieberman, William E. Paul
    Pages 117-139

  7. Histocompatibility Systems, Immune Response, and Disease in Man

    • Peter J. Morris
    Pages 141-169

  8. Antigen-Binding Receptors on Lymphocytes

    • Joseph M. Davie, William E. Paul
    Pages 171-192

  9. Modification of B Lymphocyte Differentiation by Anti-Immunoglobulins

    • Alexander R. Lawton III, Max D. Cooper
    Pages 193-225

  10. The Roles of T and B Lymphocytes in Self-Tolerance and Autoimmunity

    • A. C. Allison
    Pages 227-242

  11. Immunological Studies of Nude Mice

    • Henry H. Wortis
    Pages 243-263

  12. Back Matter

    Pages 265-267
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Keywords

About this book

Contemporary immunobiology is an ever-diversifying field that embraces many aspects of cellular and humoral immune responsiveness. This includes the phylogeny, ontogeny, induction, regulation, expression, and differentiation of the immune-cell series, as well as the relationship of these to the pathogenesis of many disease processes. It is clearly beyond the limitations of each volume in this series to comprehensively cover progress in each of these fields. Three general areas of contemporary investigations are discussed in the current issue: cellular events of B cell differentiation, including antigen recognition and respon­ siveness of B lymphocytes; regulation of the immune response by T cells, and the roles of this regulatory system in allotype suppression and in autoimm unity; and the genetic control of immune responses and its possible relation to disease pathogenesis. Analysis of responsiveness of B lymphocytes has been greatly aided by the availability of athymic nude mice. The immunological responsiveness of these mice to a wide range of stimuli has been reviewed and analyzed by H. H. Wortis. This article concludes with the provocative thesis that in the future "nudes will supply new rather than confirmatory data . . . (especially regarding) the develop­ ment of neoplasia. " In contrast to the studies on the congenitally athymic mice, G. F.

Editors and Affiliations

  • Oak Ridge National Laboratory, Oak Ridge, USA

    M. G. Hanna

  • University of Alabama, Birmingham, USA

    Max D. Cooper

  • The Walter and Eliza Hall Institute, Australia

    Noel L. Warner

Bibliographic Information

  • Book Title: Contemporary Topics in Immunobiology

  • Book Subtitle: Volume 3

  • Editors: M. G. Hanna, Max D. Cooper, Noel L. Warner

  • DOI: https://doi.org/10.1007/978-1-4684-3045-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1974

  • Softcover ISBN: 978-1-4684-3047-9Published: 19 March 2012

  • eBook ISBN: 978-1-4684-3045-5Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 268

  • Topics: Immunology

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