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Biology of Tumors: Surfaces, Immunology, and Comparative Pathology

  • Book
  • © 1975

Overview

Editors:
  1. Frederick F. Becker

    1. New York University School of Medicine, USA

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Part of the book series: Cancer, a compresensive treatise (C, volume 4)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xv
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  2. Spread of Tumors

    1. Front Matter

      Pages 1-1
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    2. Surfaces of Normal and Transformed Cells

      • James C. Robbins, Garth L. Nicolson
      Pages 3-54

    3. Contact Inhibition

      • Jan Pontén
      Pages 55-100

    4. Mechanisms of Cancer Invasion and Metastasis

      • Isaiah J. Fidler
      Pages 101-131

  3. Immunology

    1. Front Matter

      Pages 133-133
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    2. Studies of Soluble Transplantation and Tumor Antigens

      • Lloyd W. Law, Ettore Appella
      Pages 135-157

    3. RNA Oncogenic Virus-Associated Antigens

      • Tadao Aoki, Louis R. Sibal
      Pages 159-183

    4. DNA Virus (SV40) Induced Antigens

      • Satvir S. Tevethia, Mary J. Tevethia
      Pages 185-207

    5. Immunobiology of Chemically Induced Tumors

      • Michael R. Price, Robert W. Baldwin
      Pages 209-236

    6. Immunological Surveillance Against Tumor Cells

      • A. C. Allison
      Pages 237-258

    7. Host Immune Response to Human Tumor Antigens

      • Sidney H. Golub
      Pages 259-300

  4. Comparative Pathology

    1. Front Matter

      Pages 301-301
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    2. Comparative Aspects of Certain Cancers

      • Harold L. Stewart
      Pages 303-374

    3. Neoplasia in Poikilotherms

      • Dante G. Scarpelli
      Pages 375-410

    4. Plant Tumors

      • Armin C. Braun
      Pages 411-427

  5. Back Matter

    Pages 429-439
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Keywords

About this book

As was shown in the first two volumes of this series, great strides have been made in identifying many of the agents or classes of substances responsible for carcinogenesis and in delineating their interactions with the cell. Clearly, the aim of such studies is that, once identified, these agents can be eliminated from the environment. Yet, despite these advances and the elimination of some important carcinogenic agents, one major problem exists. It is a constant monitor of all oncologic study and diminishes the importance of every experiment and of every clinical observation. As we noted earlier, that problem is our inability to define the malignant cell. It is through studies of the fundamental biology of tumors that we seek this definition. A vast amount of information has been gathered which describes what this cell does and-to a lesser extent-how it does it. But the why evades us. We have been unable to define the malignant cell, save in broad terms by comparing it to its normal counterpart. The major problem appears to be that the malignant cell does so much. It is a chimera, mystifyingly composed of normal activities and structures, of phenotypic schizophrenia with embryonic, fetal, and adult charac­ teristics and, occasionally, a hint of an unclassifiable capacity unique to malignant cells.

Editors and Affiliations

  • New York University School of Medicine, USA

    Frederick F. Becker

Bibliographic Information

  • Book Title: Biology of Tumors: Surfaces, Immunology, and Comparative Pathology

  • Editors: Frederick F. Becker

  • Series Title: Cancer, a compresensive treatise

  • DOI: https://doi.org/10.1007/978-1-4684-2736-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1975

  • Softcover ISBN: 978-1-4684-2738-7Published: 12 May 2013

  • eBook ISBN: 978-1-4684-2736-3Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XV, 439

  • Number of Illustrations: 31 b/w illustrations

  • Topics: Oncology

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