Biology of Brain Dysfunction

1. Front Matter

   Pages i-xvii

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2. Genetic Disorders of Mucopolysaccharide Metabolism

   • Elizabeth F. Neufeld, Robert W. Barton

   Pages 1-30

3. Galactosemia: Biochemistry, Genetics, Pathophysiology, and Developmental Aspects

   • H. M. Kalckar, J. H. Kinoshita, G. N. Donnell

   Pages 31-88

4. Cytogenetic Aspects of Brain Dysfunction

   • Lillian Y. F. Hsu, Kurt Hirschhorn

   Pages 89-142

5. Disorders of Glucose Metabolism in Brain Dysfunction

   • William Sacks

   Pages 143-189

6. Effects of Viral Infections on the Brain

   • Halldor Thormar, Fu Hai Lin, Seung Chul Karl

   Pages 191-228

7. Disorders of Cerebrospinal Fluid and Brain Extracellular Fluid

   • Leon D. Prockop

   Pages 229-263

8. Disorders of Nucleic Acid Metabolism

   • William L. Nyhan

   Pages 265-300

9. Effects of Malnutrition on Brain Development

   • Myron Winick, Pedro Rosso

   Pages 301-317

10. Pathophysiology of Anoxic Brain Damage

    • Bo K. Siesjö, Fred Plum

    Pages 319-372

11. Effects of Deficiencies of Folic Acid and Vitamin B12 on Central Nervous System Function and Development

    • Victor Herbert, Glenn Tisman

    Pages 373-392

12. Back Matter

    Pages 393-403

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The growth of neurochemistry, molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systematic summa­ tion, and, of course, no one author can cope. Thus invitations for contributions were given to various experts in areas which are under active investigation, of current neurological interest, and pregnant. Although this project is relatively comprehensive, by dint of size, other topics might have been included; the selection was solely my responsibility. I believe systematic summation a virtual impossibility-indeed, hardly worth the effort. The attempt to assemble all of the sections involved in a large treatise with multiple authors inevitably results in untoward delays due to the difference in the rate at which various authors work. Therefore, the following strategy has been adopted: multiple small volumes and a relatively flexible format, with publication in order of receipt and as soon as enough chapters are assembled to make publication practical and economical. In this way, the time lag between the ideas and their emergence in print is the shortest.

• biology
• brain
• growth
• information
• molecular biology
• physiology

• New York State Institute for Basic Research in Mental Retardation, Staten Island, USA

  Gerald E. Gaull

• Mt. Sinai School of Medicine of the City University of New York, New York, USA

  Gerald E. Gaull

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