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Steroid Hormone Action and Cancer

  • Book
  • © 1976

Overview

Editors:
  1. K. M. J. Menon

    1. University of Michigan Medical School, Ann Arbor, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Jerry R. Reel

    1. Parke Davis Research Laboratories, Ann Arbor, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Molecular Endocrinology (CTME, volume 4)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-viii
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  2. Steroid-Induced, Steroid-Producing, and Steroid-Responsive Tumors

    • Roy Hertz
    Pages 1-14

  3. The Etiology of Breast Cancer

    • Marvin A. Rich, Philip Furmanski, Charles M. McGrath, Justin McCormick, Jose Russo, Herbert Soule
    Pages 15-27

  4. Selecting Endocrine Therapy in Breast Cancer

    • W. L. McGuire, K. B. Horwitz, M. De La Garza
    Pages 28-35

  5. The Metabolism of Steroid Hormones in Breast Cancer: A Reappraisal

    • S. C. Brooks
    Pages 36-50

  6. Fractionation of Diverse Steroid-Binding Proteins: Basic and Clinical Applications

    • Merry R. Sherman, Lorraine K. Miller
    Pages 51-67

  7. Mammalian Progesterone Receptors: Biosynthesis, Structure and Nuclear Binding

    • L. E. Faber, J. Saffran, T. J. Chen, W. W. Leavitt
    Pages 68-84

  8. The Mode of Action of Progestagens on Endometrial Carcinoma

    • Jerry R. Reel
    Pages 85-94

  9. Are Oral Contraceptives and Diethylstilbestrol (DES) Involved in Sex-Linked Cancer?

    • Richard A. Edgren
    Pages 95-106

  10. Radioiodinated Estrogens and Antiestrogens as Potential Imaging Agents

    • R. E. Counsell, A. Buswink, N. Korn, M. Johnson, V. Ranade, T. Yu
    Pages 107-113

  11. The Cellular Actions of Glucocorticoids in Relation to Human Neoplasms

    • E. Brad Thompson
    Pages 114-132

  12. Adrenal Steroids, Membranes and Neoplasia

    • Thomas D. Gelehrter
    Pages 133-138

  13. Active Forms and Biodynamics of the Androgen-Receptor in Various Target Tissues

    • Shutsung Liao, Stephen C. Hung, John L. Tymoczko, Tehming Liang
    Pages 139-151

  14. The Relevance of Studies on Androgen Action to Prostatic Cancer

    • W. Ian P. Mainwaring
    Pages 152-171

  15. Summary of Conference Plenary Sessions

    • K. M. J. Menon
    Pages 172-175

  16. Back Matter

    Pages 176-182
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Keywords

About this book

This volume is an outgrowth of a symposium held at the University of Michigan, Ann Arbor, Michigan, October 27-29, 1975. This symposium was organized to bring together basic scientists and clinicians for the purpose of exchanging new ideas and the latest information in the area of Steroid Hormone Action and Cancer. The design of the symposium included both formal plenary sessions and informal roundtable discussion groups, the chapters of this volume being drawn primarily from these proceedings. During the last quarter of a century considerable progress has been made toward understanding the molecular mechanisms in­ volved in steroid hormone action. It now appears that the mechan­ sim of action of the four major classes of steroid hormones is qualitatively similar. Research during the past decade has demonstrated steroid hormone receptors in a variety of normal and neoplastic tissues. Receptor-containing neoplasms have been shown to be hormone-dependent and undergo regression when treated with hormone antagonists. Natural and synthetic steroids also have been employed for many years to successfully treat various types of cancer, for example: estrogens, androgens and progestagens for breast cancer; estrogens and progestagens for prostatic carcinoma; progestagens for endometrial carcinoma; and corticoids for leu­ kemias. All of these neoplasms have now been found to possess receptors for the steroids empirically used in their treatment.

Editors and Affiliations

  • University of Michigan Medical School, Ann Arbor, USA

    K. M. J. Menon

  • Parke Davis Research Laboratories, Ann Arbor, USA

    Jerry R. Reel

Bibliographic Information

  • Book Title: Steroid Hormone Action and Cancer

  • Editors: K. M. J. Menon, Jerry R. Reel

  • Series Title: Current Topics in Molecular Endocrinology

  • DOI: https://doi.org/10.1007/978-1-4684-2601-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1976

  • Softcover ISBN: 978-1-4684-2603-8Published: 24 December 2012

  • eBook ISBN: 978-1-4684-2601-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 182

  • Topics: Diabetes

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