Overview
- Editors:
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Frederick R. Singer
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UCLA School of Medicine, University of California at Los Angeles, USA
Bone Center, Cedars-Sinai Medical Center, Los Angeles, USA
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Stanley Wallach
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Department of Internal Medicine, University of South Florida College of Medicine, Tampa, USA
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Table of contents (15 papers)
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- Frederick R. Singer, Karla Ginger
Pages 75-85
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- Pierre J. Meunier, Alain Ravault
Pages 86-99
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- John A. Kanis, Eugene V. McCloskey, Declan O’Doherty, Neveen A. T. Hamdy, Derek Bickerstaff, Monique Beneton et al.
Pages 112-134
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- Charles Nagant de Deuxchaisnes, Jean-Pierre Devogelaer
Pages 135-165
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- Peter Burckhardt, D. Thiébaud
Pages 166-175
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- Stephen M. Krane, Susan F. Kroop
Pages 191-199
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Back Matter
Pages 215-313
About this book
Paget's disease is an old disease historically, but a new disease therapeutic ally. Human remains unearthed in Lancashire, England, dating from ap proximately 900 AD, show clear evidence of the aftliction. However, it was not until the 1800s that physicians rediscovered the condition, and a little more than 100 years ago that Sir James Paget published a perceptive and accurate description of the disease from the clinical and pathologic points of view. He felt the disease represented an inflammatory condition of the skeleton and hence named it osteitis deformans. The condition again lapsed into anonymity for several decades afterwards, and therapeutic approaches did not evolve until after World War II when several groups, located mainly in the Boston area, began using a variety of agents, includ ing corticosteroids for treatment of this condition. These early attempts at therapy were unsuccessful and the condition remained essentially untreat able until the development of the calcitonins and the bisphosphonates in the 1970s. In 1978, the Paget's Disease Foundation, a private nonprofit volun tary health agency, was founded to assist individuals aftlicted by Paget's disease of bone, to provide education regarding this condition to the medical community, and to encourage research efforts to better under stand and treat the condition. An international conference was organized under the aegis of the Paget's Disease Foundation and was held in New York City in October, 1989, ten years after the founding of the Paget's Disease Foundation.
Editors and Affiliations
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UCLA School of Medicine, University of California at Los Angeles, USA
Frederick R. Singer
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Bone Center, Cedars-Sinai Medical Center, Los Angeles, USA
Frederick R. Singer
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Department of Internal Medicine, University of South Florida College of Medicine, Tampa, USA
Stanley Wallach